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Excess Hypothalamic Secretion Hypersecreting Thyroid Tumor

Hypothalamus

Pituitary Gland

Excess Pituitary Secretion

Thyroid Gland

Presence of TSI
Excess THYROID HORMONE T3 T4

Hypermetabolic State

Sympathetic Activity

Cardiac Effects

General Metabolic Rate

Proliferation of Cathecholamines Receptor

Overall BMR

Heart rate and contracti lity

Peripheral vasodilation due to heat load

Heat intoleran ce and excessiv e sweating

Skin become soft, warm and

Sympathetic Effects (THYROID STORM)

Cardi ac output

Palpitation and Tachycardia

Ocular- symphathetic overstimulation wide gaze, lid lag Overstimulation of gut hyper motility diarrhea, malabsorption CNS overtimulation nervous irritability and

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