Cagayan State University Andrews Campus, Caritan, Tuguegarao City COLLEGE OF EDUCATION Biochemistry Prelim Examination I.

Multiple Choice: Choose the correct answer by shading the circle which corresponds to the letter of your choice on the answer sheet provided. 1. Which is not a concern of Biochemistry? A. formulating pesticides for crops B. prescribing medicines for dengue fever C. refining a natural gas like gasoline D. determining amount of food calorie in the body 2. Biochemistry investigates the reaction of harmful drug that is accidentally swallowed by a child. Which of the following branch of science is associated to this task? A. Pharmacology C. Toxicology B. Genetics D. Immunology 3. Who proved that organic molecules can be prepared artificially using inorganic compound? A. Neuberg B. Wohler C. Buchner D.Payen 4. Which of the following is a manifestation that Biochemistry has advanced with the development of new techniques? It is through the use/conduct of _____________. A. electron microscopy C. X-ray diffraction B. NMR spectroscopy D. all of these 5. More recently, Andrew Z. Fire and Craig C. Mello received the 2006 Nobel Prize for discovering the role of RNA interference (RNAi)? What is the biological function of this molecule? A. to silence the gene expression C. to sequence the nucleotides B. to code proteins D. to induce protein synthesis 6. What is the old name of Biochemistry? A. Clinical Chemistry B. Physiological Chemistry C. Animal Chemistry D Plant Chemistry d. nucleus

7. Which of the following structure is not found in prokaryotes? a. DNA b. cell membrane c. cytoplasm

8. Which of the following is mismatched? a. protein : amino acid c. carbohydrate : monosaccharide b. lipid : fatty and glycerol d. nucleic acid : DNA 9. All are functional groups of molecule with biological significance except one, which of these? a. ether b. aldehyde c. ammonium d. amide 10.The compound fructose has C=O on its 2nd carbon. What functional group is present in this molecule? a. aldehyde b. ester c. carboxylic acid d. ketone

11. Ammonia, hydrogen sulfide and water molecules have high electrostatic linkage. Which of the following types of bond link the atoms of the above molecules? a. hydrogen bond c. ionic bond b. polar bond d. covalent bond 12. Which of the following best describes a water molecule? a. nonpolar and forms a hydrogen bond b. polar and ionic c. polar covalent that forms a hydrogen bond and has a dipole moment d. nonpolar covalent and has a dipole moment 13. Which illustrates the cohesiveness of water molecules? a. Sand sinks because it is denser than water. b. Water strider stays on the surface of the water. c. Needle is pointed object thus it can break water molecules. d. Water continuously rises up through narrow vascular bundles of the root to the shoot. 14. Which of the following shows the hydrogen bonding formation between water molecule and amino acid serine? a.

15. Water changes more slowly than do other compounds when gaining or losing energy. Which of the following property of water explains that statement? a. high heat capacity c. heat of vaporization b. high heat of fusion d. surface tension 16. When macromolecule proteins are formed through synthesis of smaller molecules of amino acid, the type of metabolism involved is ______________. a. anabolism c. catabolism b. decomposition d. both anabolism and catabolism 17. How many H-bonds can be formed in a molecule of water? a. 4 b. 2 c. 1 d. 3 18. It is the general structure of protein? a.

19. Prokaryotic cells have simpler structure than eukaryotic cells. Which of the following chiefly explains this basic distinctive feature? The prokaryotic cells ________. A. do not have nuclear envelope B. have membrane-bound DNA C. are microscopic D. do not have cytoplasm 20. Why are amino acids characterized as amphoteric? A. They have hydrophobic and hydrophilic features. B. They undergo catabolic and anabolic processes C. They have acidic and basic ends.

D. They have polar and nonpolar nature. 21. Which of the following statement concerning amino acid is incorrect? A. There are 20 mammalian amino acids. B. All amino acids have low pH. C. All amino acids are able to form a peptide bond. D. Not all amino acids have amino group. 22. How is peptide bond formed? It is formed by _____________. A. addition of water molecules B. elimination of water molecules C. addition of carboxylic acid group D. elimination of amino group 23. Which of the following functional groups is an important component of cysteine and methionine? a. SH b. OH c. NH3+ d. COOH 24. Which food is not rich in protein? a. potato c. grain legumes b. red and white meat d. peanut 25. There are amino acids that cannot be synthesized in the cells of the body. How do you classify these proteins and what are some of its examples? A. Essential amino acids: his, trp, met B. Non-essential amino acids: try, cys, pro C. Essential amino acids: gly, asp, ser D. Non-essential amino acids: glu, ala, asp 26. At low pH, what is the overall charge of amino acid? a. 0 b. + c. d. a or b if it ranges from 1-2
27. Which of the following best describes the cell shown below?

A. B. C. D.

Prokaryotic with complex structure. Eukaryotic with nuclear bound DNA. Prokaryotic which lacks organelles and no nucleus. Eukaryotic with organized and complete structures.

28. What is the name of the dipeptide molecule produced through the chemical reaction as shown below:

a. Glycylalanine b. Valylalanine

c. Alanylvaline d. Leucylglycine

29. What makes protein a Zwitterions? A. Has both positive and negative ends. b. Has hydrophobic head and hydrophilic tail.

c. Has both acidic and basic group of molecules. d. Has both polar and nopolar ends. 30. Which is NOT a conjugated protein? a. chromoprotein c. nucleoprotein b. glycoprotein d. crude protein 17. The following are groups of amino acids that cannot be synthesized in the body except one, which of these? a. histdinine, tryptophan, valine c. tyrosine, proline, cystein b. phenylalanine, leucine, isoleucine d. lysine, arginine, methionine 18. Which of the following statements concerning amino acid is INCORRECT? E. There are 8 essential amino acids. F. All amino acids have low pH. G. All amino acids are able to form a peptide bond. H. All amino acids have Nitrogen atom. 19. How is peptide bond formed? Its formation causes _____________. E. addition of water molecules c. elimination of water molecules F. addition of carboxylic acid group d. elimination of amino group 20. Genie always suffers from colds and cough. She is susceptible to diseases may be because of protein deficiency. Which of the following proteins must be administered to Genie in order to increase his bodys resistance? a. myosin b. albumin c. hemoglobin d. immunoglobulin 21. Which of the following pair is mismatched? a. collagen : muscle c. myosin : contractile tissue b. keratin : bone d. hemoglobin : red blood cell 22. Protein insulin regulates blood sugar in the body. What is the classification of insulin? a. fibrous hormone c. globular hormone b. fibrous enzyme d. globular enzyme 23. Proteins serve as biological catalysts. Which of the following explains this particular role of protein? This is because of __________________________. a. Enzyme that carries oxygen in the blood. b. Hormones that coordinates chemical reactions in the body. c. Enzymes that regulate biochemical reactions. d. Hormones that manufacture vital body compounds. 24. How do proteins differ from one another? a. the peptide bonds linking amino acids differ from protein to protein b. the sequence of amino acids differ from protein to protein c. tha carboxylic group and amino group differ from protein to protein

d. the number of Nitrogen atoms in each amino acid differs from the number in all others. 30. If cell is capable of protein synthesis, which must be present in cell? a. chloroplast b. ribosome c. lysosomes d. nucleus 31. The cell membrane regulates the flow of materials between cytoplasm and its environment? Which of the following best describe this phenomenon? Cell membrane is _____ a. differentially permeable b. rich in cytoplasm c. an elastic structure d. complementary to the structure of the entering substances 32. Which organelles sorts, chemically modifies and packages newly synthesized proteins? a. chloroplast b. mitochondria c. golgi complex d. vacuoles 33. Which of the following correctly characterizes cell wall? a. It is a flexible structure. b. It promotes excessive uptake of water. c. It holds the plant up against the force of gravity. d. Its microfibril is made up of indigestible proteins. 34. Which type of cell would probably provide the best opportunity to study lysosomes? a. skin cell b. bone cell c. bacterial cell d. nerve cell 35. Which of the following structure- function pairs is mismatched? a. nucleus; directs intracellular activities b. lysosome; intracellular digestion c. mitochondria : site of energy production d. chloroplast : site of protein synthesis 36. Cyanide poison binds with at least one of the molecules involved in the production of ATP. Following exposure of a cell to cyanide, most of this poison could be expected to be found within the _________________. a. mitochondria c. endoplasmic reticulum (ER) b. ribosomes d. golgi complex 37. Which of the following cell structures includes all others in the list? a. mitochondria b. cytoplasm c. ribosome d. chloroplast

II. MORSE CODE The phrases in the right are related to one or all items on the left side. On the space provided write: C if the item is related to the first term only.

S if the item is related to the second term only. U if the item is related to the third term only. A if the item is related to all the three terms. A. Collagen B. Enzyme C. Keratin ____1. ____2. ____3. ____4. ____5. ____1. ____2. ____3. ____4. ____5. ____1. ____2. ____3. ____4. ____5. ____1. ____2. ____3. ____4. ____5. Have(s) disulfide bonds in the hair found in the skin and bones Regulator(s) of biochemical processes contain(s) amino and carboxylic acid group found in porcupine gills, hooves and horn Attachment(s) of side chain Have(s) a pH higher than 7 COOH Have(s) hydrogen bond and it is polar composition(s) of amphoteric molecule Have(s) additional NH3+ Have(s) additional hydroxyl group coded by DNA Proline Have(s) pH ranging from 8-14 biologic catalyst(s) biochemical name of egg white globular protein(s) Carrier(s) of oxygen Increase(s) bodys resistance Prepared by: JHOANNA B. CALUBAQUIB, Ph.D. Subject-Professor Approved: JOSEPHINE M. CUE, Ph.D. BEEd Chair

A. - Carbon B. Amino group C. Carboxylic acid group

A. Basic amino acid B. Polar amino acid C. Acidic amino acid

A. Hemoglobin B. Albumin C. Immunoglobulin