DRUG STUDY

Generic/Bran d Name Clarithromyci n/Blaxin Dosage/F requency 500mg 1tab OD Classifi cation Macroli de Antibiot ic Indication Treatme nt of URIs caused by streptoc occus pyogene s, S.pneu moniae Treatme nt of lower respi infection s caused by mycopla sma pneumo niae, H.influe nzae Treatme nt of mild to moderat Contraindication Hypersensiti vity to clarithromyc in,erythromy cin, or any macrolide antibiotic Use cautionusly with colitis,hepati c or renal impairment, pregnancy,l actation Adverse Effects CNS: dizziness,HA,v ertigo,fatigue GI: diarrhea,abdo minal pain,nausea,m elena ,vomiting, Nursing Responsibilities Culture infection before therapy Do not cut or crush, and ensure that patient does not chew ER tablets Administer without regard to meals; administer with food if GI effects occur Report severe or watery diarrhea, severe nausea or vomiting, rash or itching mouth sores,vaginal sores

e CAP Treatme nt of dissemi nated mycoba cterial infection s Mucolyti c adjuvant therapy for abnorm al, viscid,or inspissat ed mucus secretio ns in acute and chronic broncho pulmona ry disease (TB) Bronchi al asthma and pulmona

Acetylcystein e/acetadote

600mg 1tab OD

Antidot e Mucom yst

Hypersensiti vity to acetylcystei ne; use caution and discontinue immediately if bronchospas m occurs.

GI: nausea, stomatitis Hypersensitivit y: urticaria Respi: Bronchospasm especially in asthma patients Other: Rhinorrhea

Assess wt,lesions,BP,P,R ,liver palpation Inform patient that nebulization may produce an initial disagreeable odor, but it will soon disappear

Doxofylline/A nsimar tab

400mg tab BID

Bronch odilator

Hypersensiti vity to ansimar and to its components.

N/V, epigastri c pain,irrit ability,in

Maybe taken with or without food

ry diseases with spastic bronchia l compon ent Moriamin forte/ calcium panthothenic 1cap OD Multivit amins and mineral s For vit. Defecie ncies and as a supplem ent For anemia and malnutri tion

Patients with MI and hypotension Contraindica ted to nursing mothers Contraindica ted to patients with malabsorpti on syndrome

somnia tachycar dia

Store at room temperature not exceeding 30C

Nausea, GI upset, constipa tion and HA, hyperph agia

Take with or without foods, maybe taken with meals for better absorption or oil discomfort occurs. May discolor urine yellow Do not drink milk prior to drinking this drug. Take it 1hour before or 2 hours after to prevent malabsorption. Assess VS, LFTs, culture area involved Decrease dosage in case of hepatic failure Give oral capsule with meals to

Itraconazole/ Sporanox

100mg 1cap BID

antifun gal

Treatme nt of fungal, candidia sis infection s of the esophag us or

Hypersensiti vity to itroconazole or other azoles, lactation, heart failure, history of prolonged

CNS: HA, dizziness CV: Heart failure GI: N/V, diarrhea, abdominal

mouth

QTc interval Use cautiously with hepatic impairment and pregnancy pain, anorexia, hepatic function abnormality Other: rash, edema, fever, malaise

facilitate absorption Do not administer to patients with evidence of cardiac dysfunction or heart failure; risk or severe heart failure Report unusual fatigue,anorexia, vomiting,jaundic e,dark urine,pale stool,edema,DO B Do not give IM injection of more than 600mg; inject deep into large muscle to avoid serious problems Monitor renal and liver function test and blood counts with prolonged therapy Report sever/watery diarrhea.

Clindamycin/ Clindamycin Phosphate

300mg 1cap OD

Lincosa mide antibiot ic

Serious infection s caused by suscepti ble strains of anaerob s,strept ococci reserves use for penicilli nallergic patients /when

Allergic to clindamycin, history of asthma or other allergies

CV: hypotension cardiac arrest GI: severe colitis, N/V, diarrhea, abdominal pain

penicilli n is inappro priate;le ss toxic antibioti c(erythr omycin) chould be consider ed

Abdominal pain,inflamed mouth or vagina,skin rash/lesion