HUMAN PHYSIOLOGY 201 Course Syllabus*

Winter Term 2012 COURSE DIRECTOR: Elizabeth M. Rust, Ph.D. Office: 7708b Med Sci II Phone: 615-3173 E-Mail: emrust@umich.edu Office Hours: TBD COURSE ADMINISTRATOR: Michele Boggs Office: 7744 Med Sci II Phone: 936-2355 E-Mail: mboggs@umich.edu

TEXTBOOK: VANDERS HUMAN PHYSIOLOGY: The Mechanisms of Body Function. E.P. Widmaier, H. Raff and K.T. Strang, McGrawHill Book Company, 12th Edition, 2010 with CONNECT. LECTURE FIGURES: Available on the web site. Contains most of the figures used in lecture. Each unit will have its own folder. You may print them at your convenience to bring to class. The files are Powerpoint files, which can be printed as handouts with 2-9 slides per page. Slides are in color. ONLINE INTRODUCTORY COURSE MATERIAL: COURSE WEB SITE: LECTURES:

REQUIRED.

See page 8 for details.

Go to ctools.umich.edu/portal. Login. Click on the Physiol 201 tab.

M-W-F from 10:10 11:30 AM. Lecture will start promptly at 10:10 AM. I will send the room as soon as I have the information. It will be at the Medical School See map on next page for Med School Building locations: First Lecture: Wed., January 4, 2012

DISCUSSION SECTIONS: Optional, but can receive extra credit points by attending. See page 7 for more details. OFFICE HOURS: I will post open office hours, for which you do not need an appointment. If you cannot make these scheduled office hours, or if you have a matter to discuss which requires privacy, you are welcome to make an individual appointment with me at another time. REQUIRED ITEM: Flash Drive or Jump Drive or Thumb Drive or CDsome sort of portable mass storage device. Homeworks should be saved on this device often. Computer crashes, virus on computer, UM computer discarded your paper, etc, are all unacceptable excuses for not submitting or late submission.

*Revised 1/10/2012- Policies and information are subject to revision and/or modification at any point at the discretion of the course director.

Physiology 201 Winter 2012

207 = Med Sci II (MS II), the circular portion on the left is where NLH, WLH and SLH are located ( 3rd floor). Also, FSSC (Furstenberg) rooms are on 2nd floor of MS II: 2710, 2733, 2737 Buhl = very front of 207, closest to Catherine St., location of room 5915 203 = Med Sci I, A Wing (MS I), location of 3330 and 5330 on 3rd and 5th floor respectively. 208 = Taubman Medical Library, location of 2901 and 2903 Parking areas are open to the public at 6 PM. Doors to Med Sci II are locked by 5:30 PM, but can gain access via Taubman Library doors, which are open. Take hallway to right, then doorway on right into Med Sci II.

Physiology 201 Winter 2012

Lecture Schedule:
Lect 1 Date Jan 4 Day W Topic Intro. to the Course Framework/Homeostasis Introductory Quizzes Available Membrane Potential Content Quiz 1 available

Unit 1
Chap. 1 Pages
11th: 1-13 12th: 1-15 11th: 138-157 12th:: 142-147 11th: 138-157 12th: 147-155 11th: 159-186 12th: 156-165
11th: 192-200, 206-216 12th: 169-181, 187-196

Meeting Room 5330, Med Sci I

5330, Med Sci I

Membrane Potential and Excitable Cells 6 Finish Excitable Cells Neural Tissues and Synapses Introductory Quizzes are Due! Nervous System Structure Sensory Physiology - Intro Content Quiz 2 available MLK Day- No Class Vision Homework 1 due Hormones 11 6

5330

11

5330

13

5330

6 7 8

16 18 20

M W F

11th: 206-216 12th: 202-212 11th: 317-336, 342-345 12th: 312-331

5330 5330

Jan 23

Exam 1

5330 + 2nd room TBD

Important Due Dates: Unit 1 1. Tues. 1/10: 2. Fri. 1/13: 3. Tues. 1/17: 4. Fri. 1/20: 5. Mon. 1/23:

Content Quiz 1 Introductory Quiz 1 and Introductory Quiz 2 Content Quiz 2 Homework 1 due Exam 1. 8 lectures. 41 questions.

Physiology 201 Winter 2012

4
Chap. 9 9 Pages
11th: 255-263 12th: 251-259 11th: 261-274 12th: 259-269

Lecture Schedule:
Lect 1 2 Date 25 27 Day W F

Unit 2
Topic Muscle: Skeletal- Introduction, Sarcomere, filaments Muscle: Skeletal- NMJ, single fiber mechanics, fatigue Content Quiz 3 available Skeletal Muscle-Whole Muscle & dysfunction Smooth Muscle Homework 2 Due Cardiovascular system- Blood, F = P/R, Anatomy, Cardiac Muscle, Conducting System, ECG, Content Quiz 4 available CV: Cardiac Cycle, Valves/murmurs, CO, SV, HR, VR
CV: Blood vessels, Autonomic and hormonal inputs, Capillary exchange, lymph

Meeting Room 5330, Med Sci I

5330

3
4 5

Jan 30 Feb 1 3

M W F

9 9 9&12

11th: 274-280 12th: 269-274 11th: 284-290 12th: 279-285

11th:290-291, 360-382 12th: 285-287, 354-367

5330 5330 5330

6 7 8

Feb.

6 8 10

M W F

12 12

11th: 384-403 12th : 367-375 11th: 405-424 12th: 377-395 11th: 413-424 12th: 397-402

5330 5330 5330

CV: Regulation of Blood Pressure 12 Content Quiz 5 available Complete previous lecture Exercise/Training, Heart Disease CV: Hemostasis (blood clotting) Homework 3 due

9 10 11 12 13

Feb. 13 15 17 Feb 20

M W F M W

12
12

12th: 405-416 11th: 425-437 12th: 417-427

5330 5330

5330
5330 5330, Med Sci I + 2nd room TBD

Feb 22

Overflow Lecture Exam 2

Important Due Dates for Unit 2 1. Tues. 1/31 Content Quiz 3 2. Fri. 2/4 Homework 2 3. Tues. 2/7: Content Quiz 4 4. Tues. 2/14: Content Quiz 5 5. Mon. 2/20: Homework 3 due 6. Wed. 2/22 Exam 2: 12 lectures. 46 questions.

Physiology 201 Winter 2012

Lecture Schedule:
Lect 1 Date Feb 24 Day F Topic Respiration-Mechanics, Compliance

Unit 3
Chapter 13 Pages
11th: 443-457 12th: 435-445

Meeting Room 5330, Med Sci I

Feb 25Mar 4
2 3 4 Mar. 5 7 9 M W F

Winter Break

No Class
12th: 445-448

5330

Respiration- Airway resistance Respiration-O2/CO2 Exchange

/Transport

5330 5330 5330

13 13

11th: 457-469 12th: 448-459 11th : 469-478 12th: 460-468

Respiration: Regulation of breathing

Content Quiz 6 available

5 6 7

Mar. 10 12 14

M W F

Video: Everest, The Death Zone

Renal- Basic Processes, GFR, Glucose, Na+ and H2O handling

5330
14 14 14
11th: 486-503 12th: 476-491 11th: 503-515 12th: 491-503

5330 5330

Homework 4 Due Renal- Na+,H2O, & K+ Regulation

Content Quiz 7 available

8 9 10

Mar. 19 21 23

M W F

Renal- Volume and Osmolarity Problems Renal- H+ Regulation Renal- Ca2+ and Kidney Failure 14
10th: Ch.14 11th: Ch. 11 and Ch. 14 11th: 517-522 12th: 506-511
11th: 352-355, 523-525 12th: 345-348, 503-504, 512-514

5330 5330 5330

11 12

Mar. 26

Homework 5 Due Overflow lecture

5330
5330, Med Sci I + 2nd room TBD

28

Exam 3

Important Due Dates for Unit 3: 1. Mon. 3/10 Homework 4 2. Tues. 3/11: Content Quiz 6 3. Tues 3/20: Content Quiz 7 4. Mon. 3/26: Homework 5 5. Wed. 3/28: Exam 3. 11 lectures. 46 questions.

Physiology 201 Winter 2012

Lecture Schedule:
Lect 1 Date Mar 28 Day W

Unit 4, Final Exam

Chapter 15 Pages
11th: 528540 12th: 517528 11th: 540557 12th: 528544

Topic GI- Basic Processes

Meeting Room 5330, Med Sci I

30

GI- Regulation of GI processes

Content Quiz 8 available

15

5330

3 4

Apr

2 4

M W

Finish GI/Start Endocrine Endocrine- Metabolism Absorptive/Postabsorptive states Endocrine- Metabolic Regulators
Diabetes Case/Problem Content Quiz 9- available

16

16

11th: 567578 12th: 555560 11th: 578582 12th: 560567, 581583 11th:599-613 12th:587-600 11th:615-627 12th:603-614 11th:627-640 12th: 614627

5330 5330

5330

6 7 8

9 11 13

M W F

Reproduction- General Principles and Male Reproduction Homework 6 Due Reproduction- Female Reproduction-Pregnancy, parturition and lactation

17 17 17

5330 5330 5330

16 April 23

M Mon

Exam 4
Final Exam: Cumulative over 4:00 PM 6:00 PM

5330, Med Sci I + 2nd room TBD Rooms TBD

Important Due Dates: Unit 4 1. Tues. 4/3: 2. Tues. 4/10: 3. Wed. 4/11: 4. Mon. 4/16: 5. Mon. 4/23:

Content Quiz 8 Content Quiz 9 Homework 6 Exam 4. 8 lectures. 41 Questions Cumulative Final Exam. 72 Questions.

Physiology 201 Winter 2012

DISCUSSION SECTIONS
Attendance at Discussion Section is optional, HOWEVER, attendance will be taken, and you can gain up to 0.25% extra credit for attending the section for which you are registered, based on the following attendance schedule: Number of Absences 0-3 4-6 7-9 10-13 Extra Credit Received 0.25% 0.15% 0.1% 0

You will receive the extra credit only if you attend the section for which you are registered. You are permitted to miss 3 discussion sessions for any reason and still receive full attendance extra credit. With more than 3 absences, extra credit is reduced as shown, with no exceptions or excuses considered. Every student is allowed 3-and-only-3 absences to receive the full bonus. If more than 3 absences occur, for ANY reason, then extra credit is reduced as described above. Therefore, wisely use your allowed absences. Skipping 3 early sessions and then missing due to sickness later in the semester will not gain you any additional allowed absences. The % extra credit will be added to your final course grade. 2739/2743 are on the 2nd floor of Med Sci II Bldg in an area called the FSSC. TML stands for Taubman Medical Library. 2901 is on the 2nd floor of the library.

. See map on page 2 for locations of rooms. Section Day Time First # Meeting 002 003 004 005 006 007 Thursday Thursday Friday Friday Friday Thursday 9:00 AM 9:00 AM 9:00 AM 9:00 AM 9:00 AM 9:00 AM Jan. 12 Jan. 12 Jan. 13 Jan. 13 Jan. 13 Jan. 12

Room # (First Meeting) 2739 MS II 2743 MS II 2813 MS II 2817 MS II 5330 MS I 2901 TML

Instructor

Jacob Bermudez (jbermu) Gail Butler (gcbutler) Chun-Shu Wong (chuwong) Bryan Holtz (bjholtz) Joel McDade (jmcdade) Joel McDade (jmcade)

***THE FIRST DISCUSSION SECTIONS WILL MEET ON:*** Thursday, January 12, 2011 Friday, January 13, 2011

Physiology 201 Winter 2012

ONLINE (REQUIRED) INTRODUCTORY TUTORIALS AND QUIZZES

On the Physiology Ctools web site, in Resources, there is a folder titled A. Introductory Course Material. Within this folder are four files, two of slides and two of associated notes for this background material. The slide and note files list text readings that coincide with the slides and notes. There are also two LINKS to the quizzes in UMLessons. You should study this material ON YOUR OWN and then take the quizzes that are located on UMLessons. Introductory Quiz 1 has 20 questions and is worth 20 points. Introductory Quiz 2 has 10 questions and is worth 10 points. The quizzes will be available for you to take between January 4, 2012 and January 13, 2012. You MUST submit the quizzes by 11:59 PM on Friday, January 13. You can take each quiz as many times as you want until you achieve 100% or an acceptable score for you. The quiz questions and question answers will be shuffled with each attempt, so you will not see the exact same quiz each time you attempt it. These quizzes are REQUIRED. If you do not take them you will lose 30 points. This introductory quiz material is NOT questioned directly on Exam 1.

ONLINE COURSE CONTENT QUIZZES

At the end of most weeks, an online quiz will be posted. These Content Quizzes will be available via the Test Center tool on the CTools website. You will have from ~5 PM on Friday until Tuesday (due time will be posted with the Quiz- you must pay attention to it). See the Lecture Schedule on pages 3-6 for the quiz dates. Quiz material will cover untested/unquizzed lecture material presented prior to the quiz due date. You can take each quiz one (1) time in the time period that it is available. Quizzes 1-9 are worth 5 points each, and 1 score will be dropped.

EXAMINATIONS
Course examinations will be based upon the subject matter presented in lecture, and test questions will be drawn from the lecture material. The textbook is highly recommended, but lecture material and figures should receive priority when studying for the exam. There will be 4 objective examinations in class during the semester and a Final Exam is cumulative over Units 1-4. These objective examinations will consist of multiple choice, matching and true/false questions. Statement on Cheating: Cheating will not be tolerated. If cheating is suspected for any reason, students may be asked to move to a new location, turn in their exam as is, or leave the course. After review, students may receive 0s on the exam and cases may be referred to a students dean for consideration of Academic Misconduct charges. EXAMINATION TIMES Exam Lectures Examination 1 8 lectures Examination 2 Examination 3 Examination 4 Final Exam 12 lectures 11 lectures 8 lectures Cumulative

Questions/lecture 41 total questions

~5 per lecture

46 total questions
4-5 per lecture

46 total questions
4-5 per lecture 41 total questions ~5 per lecture

72 total questions
1-2 per lecture

Day/Date/Time Monday, January 23, 2012 In class Wednesday, February 22, 2012 In class Wednesday, March 28, 2012 In class Monday, April 16, 2012 In class Monday, April 23, 2012 4:00 6:00 PM

Physiology 201 Winter 2012 EXAMS ON FILE Copies of the exams from Fall, 2011 are on the Course Web Site for you to use as a study tool.

CALCULATING EXAMINATION SCORE PERCENTAGE It is recognized that an occasional question may be unintentionally written or interpreted in an ambiguous manner. It is for this reason that an extra question is asked on each exam. For Exams 2 and 3, your percentage score can be determined by dividing the number correct by 45 (1 extra question) and for Exams 1 and 4, dividing by 40 (1 extra question). For the Final Exam, your percentage score can be determined by dividing the number correct by 70 (2 extra questions). Examination scores (number of questions answered correctly) will be posted on the Ctools web site in the Gradebook Tool. Exam scores cannot be given out over the telephone or email. MISSED EXAMINATIONS- MAKEUP/ALTERNATE EXAMS For all exams, approval for a Makeup/Alternate Exam will be given to those who must travel for University-associated business or those who have a medical or emergency situation (which can be documented for me) arise before the exam. "Vacation" type trips are not valid for an excused absence at any time. I MUST BE CONTACTED BEFORE THE MISSED EXAM AND NOTIFIED OF THE PROBLEM TO DETERMINE IF IT IS VALID AND WHAT TYPE OF DOCUMENTATION IS REQUIRED. EXCEPTION IS SUDDEN EMERGENCY SITUATION REQUIRING YOUR IMMEDIATE ATTENTION THAT DEVELOPS JUST BEFORE THE EXAM IS SCHEDULED. YOU MUST THEN CONTACT ME AS SOON AS POSSIBLE TO EXPLAIN AND DISCUSS THE OPTIONS AVAILABLE. Except for documented University-associated business or documented emergency/medical situations, all students must take the exam when it is regularly scheduled. This includes the FINAL EXAM. Early exams are not offered before the scheduled day of the exam. The Makeup/Alternate Exam is a different exam (similar difficulty level) from the scheduled exam and occurs after the original exam time. Depending on circumstances, same day, but earlier time may be possible for an alternate exam. The makeup exam will be scheduled for the earliest possible time after the original exam.

HOMEWORK ASSIGNMENTS
There will be six (6) homework assignments. The assignments will be available on the web site. The value of all the assignments combined will be 120 points, with between 15-25 points per assignment. Assignments must be submitted electronically via the web site. After submission you will receive an email from CTools verifying successful submission. If you, for some reason, submit by email to me, I will reply to confirm receipt of your assignment. It is the students responsibility to verify that his/her assignment has successfully submitted. If you do not receive a verification email, then your submission was unsuccessful and you need re-submit. Due times and late submission deadlines will be clearly outlined in the assignment instructions. It is the students responsibility to know the deadlines and consequences of late submission as outlined in each assignments instructions. Absolutely no leniency on submission requirements will occur unless you require hospitalization or another similar major catastrophe/crisis which you can document occurs at/very near the time of submission. In such a case, the student must contact me as soon as he/she is aware of the issue with submitting the assignment. It is expected that notification will occur before the submission deadline

Physiology 201 Winter 2012 10 unless this is physically impossible, and as soon as reasonable possible if contact before the deadline is impossible. Late submission is not permitted for individual computer emergencies- you must have a backup file on a portable storage device and allow enough time to submit in case of a computer issue. Examples of invalid late excuses (this is NOT a complete list): y I thought I clicked submit. It is YOUR responsibility to confirm that your assignment has been posted to the web site. Check that it posted after you click submit to be sure. y My computer did something weird and the assignment disappeared. Always save a backup copy on disk or flash drive and save often! y My internet connection failed or My computer crashed or I pushed submit at 11:57, but it didnt go through until 12:01. Allow extra time for submission as it is not always instantaneous. Cheating/Plagiarism Statement: 1. You are responsible for the security of your electronic files and of hard copies of your documents. Do not send or lend your submitted homework document to anyone else. If another student (or students) submits your document, you will be held responsible and all students involved will receive a 0. Academic misconduct charges may be brought against students in such a situation. 2. You may work together on the written assignments, but answers must be submitted in your own words. Each of you has the responsibility of writing your answers in your own words. Each of you also has the responsibility of protecting your answers and not allowing others the opportunity to cheat off of you. Do not give your final answers (electronic or hard copy) to another student. If multiple students submit identical or nearly identical answers, they will ALL receive a score of 0 for that question. Academic misconduct charges may be brought against students in such a situation. 3. Plagiarism (copying) of internet, textbook or other resources without proper paraphrasing and/or citation is also not permitted. All answers must be in your own words. Academic misconduct charges may be filed if plagiarism is discovered. It is also unacceptable to quote resources, even with proper citation. You must write the answer in your own words. Although not an academic misconduct issue, a quoted answer with citation will receive a 0 for failure to follow instructions.

Grading of Assignments: The assignments will be graded by the GSIs or Dr. Rust. Each GSI will grade one (1) assignment for ALL students. In other words, a single grader will be grading all ~180 student papers. Due to the large number of students in the class, grading may take 2-3 weeks to complete. Grades will be posted online on CTools once all assignments are graded. Assignments will be returned via the CTools website.

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ADDITIONAL COURSE CREDIT

ATTENDANCE AT DISCUSSION SECTIONS As described on page 7, you can receive up to 0.25% added to your course subtotal for attending the Discussion section for which you are registered. Attendance will be taken at Discussion. Remember, you must attend the section for which you are registered to receive credit. RETURN OF COURSE EVALUATION FORMS Near the end of the semester, you will be notified about the online questionnaire evaluating this course and its instructors. You will receive 0.25% (1/4 of a percentage point) added to your course grade for returning the Evaluation form. The evaluation is anonymous. We receive a list of all who responded, but your name is not associated with your ratings and comments.

CALCULATING COURSE GRADE

Your course grade is determined from the sum of your scores on the Introductory quizzes, Content quizzes (1 quiz dropped from the first 8 quizzes), Exams and Homework Assignments divided by the total number of points available plus any extra credit. THERE IS NO CURVE: Exam or Assignment Quizzes (Introductory = 30, Content = 40 points) Exams Written Assignments TOTAL POINTS Points Available Percentage of Final Grade 70 16.3% 240 120 430 55.8% 27.9% 100%

Example of calculating course grades:

Exam or Assignment Introductory Quizzes Content Quizzes 1-9 (drop 1 score) Unit Exams 1-4 (170 points) Cumulative Final Exam (70) Homework Assignments SUBTOTAL Discussion Evaluation Course Grade: 385/430 = Discussion Bonus Evaluation Return Adjusted Course Grade = Points Received 30 (100%) 37 (92.5%) 145 (85.3%) 60 (86%) 113 (94.2%) 385 Missed 1 Submitted 89.53% = B+ + 0.25% + 0.25% 90.03% = APoints Possible 30 40 170 70 120 430 + 0.25% + 0.25%

Course letter grades will be assigned on the following scale. Note Plus and Minus grades will be given: A+ 97-100% B+ 87-89.99% C+ 77-79.99% D+ A 93-96.99% B 83-86.99% C 73-76.99% D A90-92.99% B80-82.99% C70-72.99% D-

that grades are NOT rounded up. 67-69.99% E 63-66.99% F 60-62.99% 50-59.99% 0-49.99%