DRUG NAME

MECHANISM OF ACTION

INDICATIO N
edema due to cardiac, hepatic, or renal disorders (in the presence of nephritic syndrome, treatment of the basic disorder is the prime concern). edema due to burns. Mild to moderate hypertension.

CONTRAINDICA TION
Renal failure with lack of urine (anuria), hepatic coma and precoma, severe hypokalemia, severe hyponatremia, hypovolemia with or without hypotension, hypersensitivity to furosemide or sulphonamides.

SIDE EFFECT
o

NURSING MANAGEMN ET
o

Rapid-acting potent sulfonamide loop BRAND NAME diuretic and antihypertensive with : Lasi pharmacologic effects and uses x almost identical to those of ethacrynic acid. Exact mode of action not clearly defined; decreases renal vascular resistance and may GENEREC increase renal blood NAME: flow.

Increase in urinary frequen cy or volume -Nausea -Gastric upset with crampin g Diarrhe a or constipa tion Electrol yte disturba nces Dizzines s or

o o

-Give with food to avoid gastroines tinal upset, preferably with breakfast (to prevent nocturia). -Check vital signs especially blood pressure for hypotensi on prior to administr ation. -Assess edema, skin turgor, and

furos emid e

light headed ness

o

Headac he -Blurred Vision Paresth esia Photose nsitivity -Rash Weakne ss -Bladder spasm Restless ness Diaphor esis -Flank or loin

mucous membran es for hydration status.

o

o o

-Assess muscle strength and mental status. -Obtain baseline weight. -Initiate Input and Output monitorin g. -Note extent of diuresis.

o o

o o

pain

DRUG NAME

MECHANISM OF ACTION

INDICATION

CONTRAINDICATI ON

SIDE EFFECT

NURSING MANAGEMNET

BRAND NAME: Clopidogrel

GENEREC NAME: Plavix

Inhibits platelet aggregation by blocking ADP receptors on platelets, preventing clumping of platelets

-Treatment of patients at risk for ischemic eventshistory of MI, ischemic stroke, peripheral artery disease -Treatment of patients with acute coronary syndrome

-Contraindicated with allergy to clopidogrel, active pathological bleeding such as peptic ulcer or intracranial hemorrhage, lactation.

CNS-Headache, dizziness, weakness, syncope, flushing CV-Hypertension, edema DermatologicRash, pruritus GI-Nausea, GI distress, constipation, diarrhea, GI bleed Other- Increased bleeding risk

-Assess for symptoms of stroke, MI during treatment -Monitor liver function studies: AST, ALT, bilirubin, creatinine if patient is on long-term therapy -Monitor blood studies: CBC,Hgb, Hct, protime, cholesterol if the patient is on long-term therapy; thrombocytopeni a and neutropenia may occur.