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14 - 17 MARCH 2012 / ISTANBUL - TURKEY

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS


14 - 17 March 2012, Istanbul - Turkey Istanbul Lutfi Krdar Convention & Exhibition Center

FINAL PROGRAM
www.isbd2012.org

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

WELCOME
Dear Colleagues, We would like to welcome you to the 5th Biennial Conference of the International Society for Bipolar Disorders and stanbul, Turkey for this 4 day program from 14 - 17 March 2012. We hope you enjoy your time in stanbul, the melting pot of continents and cultures over centuries. The Istanbul Lufti Kirdar Convention and Exhibition Center will serve as the sole facility for all conference related activities, including pre-conference workshops, ISBD membership, administrative and task force meetings, and satellite symposia. The ISBD is committed to inclusiveness in all its activities, and draws on its chapters and internationally recognized leaders in the field to bring you an outstanding scientific program. As referenced above, ISBD will again host a full day of activities prior to the opening ceremony of the meeting, which are part of what make the ISBD meetings a unique experience for attendees. We have arranged a series of pre-conference workshops on topics including womens health, mood stabilization and comorbidity, an experts course for young clinicians, chronotherapeutic techniques in the management of bipolar disorder, and advancement clinical topics and future trends in bipolar disorder. These workshops will offer participants the opportunity for a more interactive experience, with opportunities to discuss case vignettes. ISBD members will also not want to miss the annual General Membership Meeting, which will be held on the 14th of March at 16:00 in the Dolmabahce C Meeting Room. Among the highlights of the conference are 4 keynote presentations, including a child and adolescent debate, a bipolar spectrum session, US National Institute of Mental Health (NIMH) Updates, and a Word Psychiatric Association (WPA) address to the congress. The meeting will also feature engaging core symposia on topics including optimizing functional outcomes, interpreting clinical trials, DSM-V updates, molecular genetics, neuroimaging, and advocacy. As in years past, ISBD will also be holding an awards ceremony and special concurrent session for the winners of the Samuel Gershon Awards for Junior Investigators, as well as an International Society for Affective Disorders (ISAD) session. We trust you will find the conference to be a memorable, informative and enjoyable event. President : Mauricio Tohen Co-chairs : Ayegl zerdem and Sophia Frangou Treasurer : Ihsan Salloum

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

ISBD 2012 CONFERENCE OFFICIALS


Caleb Adler, MD University of Cincinnati USA Fisun Akdeniz, MD Ege University School of Medicine Affective Disorders Unit Turkey

ISBD 2012 FACULTY


Ellen Frank, PhD University of Pittsburgh School of Medicine USA Mark Frye, MD Mayo Clinic USA Kyooseob Ha, MD, PhD Seoul National University South Korea Chantal Henry, MD, PhD Pole de psychiatrie Hospital de Chennevier France David Kupfer, MD Univ. of Pittsburgh School of Medicine USA Rasmus Licht, MD, PhD Aarhus University Psychiatric Hospital Denmark Andrew McIntosh, MD Edinburgh University Charles Nemeroff, MD, PhD University of Miami USA Willem A. Nolen, MD, PhD University Medical Center Groningen The Netherlands Tezer Orhan Lithium Association Turkey Ayegl zerdem, MD, PhD Dokuz Eylul University Medical School Turkey Natalie Rasgon, MD, PhD Stanford University School of Medicine USA Marcella Rietschel, MD Heidelberg University/Medical Faculty Mannheim Germany Pedro Ruiz, MD University of Miami Miller School of Medicine USA Ihsan Salloum, MD, MPH University of Miami USA Manuel Sanchez de Carmona, MD ISBD Mexican Chapter Mexico Verinder Sharma, MB, BS, FRCP (C) University of Western Ontario Canada Lut Tamam, MD Cukurova University Faculty of Medicine Turkey Eric Taylor, MD Kings College London UK Mauricio Tohen, MD, DrPH, MBA University of Texas USA Simavi Vahip, MD Ege University Medicine Faculty Turkey Eduard Vieta, MD, PhD University of Barcelona Spain Lakshmi Yatham, MD, FRCPC The University of British Columbia Canada Eric Youngstrom, PhD University of North Carolina USA Carlos Zarate, MD National Institute of Mental Health, Maryland USA

President: Mauricio Tohen, MD, DrPH, MBA (USA)

Hagop Akiskal, MD VA Psychiatry Service USA Carlo Altamura, MD University of Milan Italy Michael Bauer, MD, PhD Technische Universitat Dresden Germany

Co-Chair: Aysegul Ozerdem, MD, PhD (Turkey)

Robert Belmaker, MD Ben-Gurion University of the Negev Israel Michael Berk, MD, PhD Barwon Health Swanston Centre Australia Boris Birmaher, MD University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania Joseph Calabrese, MD University Hospitals Case Medical Center Case Western Reserve University USA Francesc Colom, PsyD, MSc, PhD Institute of Neurosciences, Hospital Clinic University of Barcelona Spain Allen Doederlein Depression and Bipolar Support Alliance (DBSA), USA Sophia Frangou, MD, PhD, FRCPsych Kings College London UK

Co-Chair: Sophia Frangou, MD, PhD, FRCPsych (United Kingdom)

Treasurer: Ihsan Salloum, MD, MPH (USA)

Local Organizing Committee


Omer AYDEMR, MD (Turkey) Kaan KORA, MD (Turkey) Timuin ORAL, MD (Turkey) Simavi VAHP, MD (Turkey) Olcay YAZICI, MD (Turkey)

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

ACKNOWLEDgEMENTS
We wish to express our gratitude to the following companies who through their generosity, have helped to make this Congress possible

COMPANY SPONSORED SATELLITE SYMPOSIA

Platinum Level Wednesday, March 14th 2012, Anadolu Auditorium


19:30-21:00 Making the right decisions to prevent recurrence in the long-term treatment of bipolar disorder Chair: Heinz grunze Speakers: Christoph Correll, Eduard Vieta, Michael gitlin,

Thursday, March 15th, 2012, Anadolu Auditorium Other Sponsors


11:45 13:15 A Journey from Pole to Pole: Todays challenging patient Chair: Mauricio Tohen Speakers: Timucin Oral, Eduard Vieta, Roger McIntyre 19:00 20:30 A Journey from Pole to Pole: Travelling to the Future Chair: Joseph Calabrese Speakers: Ali Saffet gonul, Lakshmi Yatham, Francesc Colom

Turkish Advocacy Forum Sponsor

Official Congress Airline

Exhibitors
CINP BIPOLAR DISORDERS ASSOCIATION OF TURKEY BIPOLAR LIFE ASSOCIATION TURKEY INTERNATONAL SOCIETY FOR BIPOLAR DISORDERS LILLY ILAC LITHIUM SOCIETY TURKEY MUSTAFA NEVZAT

Friday, March 16th, 2012, Anadolu Auditorium


12:45 14:15 Time to revisit the definition and treatment of bipolar I disorder in a Multidimensional way Chair: Michael Berk Speakers: Michael Berk, Mohammed Shahid, Andrea Fagiolini

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INTERNATIONAL SOCIETY FOR BIPOLAR DISORDER MEETINg AT THE CONgRESS


Wednesday, March 14, 2012 16:00 - 17:00 ISBD Membership Meeting Dolmabahce C, on the 1st Floor

CME ACCREDITATION
The 5th Biennial Conference of the International Society for Bipolar Disorders is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS), www.uems.net The 5th Biennial Conference of the International Society for Bipolar Disorders is designated for a maximum of 15 hours of European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

WHEREVER YOUR CONFERENCES TAKE YOU, STAR ALLIANCE CAN TAKE YOU
No matter where youre travelling from, the Star Alliance network Istanbul. offers you a wide choice of flights to < conference location .> And with over 21,000 flights a day to 1,160 destinations across 181 countries, our 27 member airlines extend the same choice to any future conferences youre planning to attend. You can also save money when you book your flights. Simply quote the unique conventions code and you and one companion travelling with you will receive a special discount. Better still, no matter which Star Alliance member airlines frequent flyer programme you belong to, you can earn and redeem miles across all 27 airlines. For more information, or to join the airline network that offers you more choice wherever your conferences take you, simply go to www.staralliance.com/conventionsplus

Through an agreement between the European Union of Medical Specialists and American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits. Information on the process to convert EACCME credit to AMA credit can be found at www.ama-assn.org/go/internationalcme Live educational activities, occurring outside of Canada, recognized by the UEMS-EACCME for ECMEC credits are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of The Royal College of Physicians and Surgeons of Canada. EACCME credits Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity. The EACCME credit system is based on 1 ECMEC per hour with a maximum of 3 ECMECs for half a day and 6 ECMECs for a full-day event.

www.staralliance.com
Information correct as at 09/2010

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

SAMUEL gERSHON AWARDS FOR JUNIOR INVESTIgATORS


The International Society for Bipolar Disorders (ISBD) recognizes the vital role of developing the next generation of leaders in the field of bipolar disorders and will offer 4 awards for original research publication submissions. In order to promote research interest in bipolar disorders in developing countries, two of the awards will be reserved for those from low and middle-income countries, as defined by the 2011 World Bank Classification. The awards are presented in conjunction with the 5th Biennial Conference of the International Society for Bipolar Disorders to be held in Istanbul from 14-17 March 2012. The Samuel gershon Awards 2012 Winners Rasim Somer Diler, MD Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA, USA Jan-Marie Kozicky, PhD Department of Psychiatry, University of British Columbia, Vancouver, BC Canada Pedro Vieira da Silva Magalhes, MD, PhD National Institute for Translational Medicine, Hospital de Clnicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil Cristian Zeni, MD Federal University of Rio Grande do Sul, Brazil

GENERAL INFORMATION

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

gENERAL INFORMATION
Venue Istanbul Ltfi Krdar Convention & Exhibition Centre (ICEC) Harbiye, 34267, Istanbul - Turkey Tel: +90 212 3731100 www.icec.org Registration Desk Registration desk will be open during the below dates and times at the main foyer of the Congress Center, Istanbul Lutfi Kirdar Convention Center - ICEC. Registration Desk Hours March 14, 2012 Registration for Workshops, Registration for ISBD 2012 March 15 & March 16, 2012 Registration for ISBD 2012 March 17, 2012 Registration for ISBD 2012

Certificate of Attendance Delegates will be able to receive their certificate of attendance from the registration desk Opening Ceremony & Welcome Reception Opening Ceremony will be organized on March 14, 2012 between 17.00 and 18.00, at the Anadolu Auditorium of ICEC. After the ceremony the Welcome Reception will be organized at the main foyer of the Anadolu Auditorium at ICEC. All registered delegates and accompanying persons will be able to attend to these events. Please wear your name badges for entrance to the Welcome Reception. Lunch Lunch boxes will be served on March 15th & March 16th. However, cash bars and A la Carte restaurant will be available in the conference venue for the service of attendees. There are also lots of different cuisine and restaurant options around the conference venue. Necessary information reaching to various options for lunch can be obtained from the Information Desk. Posters The Poster boards are sponsored by J&J. Posters are located in the 1st floor of the congress center. Poster Sessions will take place on Thursday, March 15 and Friday, March 16. Slide Control Room / Speaker Ready Room Delegates who will present their papers should submit their presentation files at least two hours before their presentation. The Slide Control Room will be on the first floor of the conference venue and the name of the room is Dolmabahce B. It is advised to load the presentations to the Speaker Ready Room at least two hours before the session starts. If your presentation is early in the morning, it is advised to load the presentation the day before. Internet Cafe An internet cafe will be free to use it during the conference. Information & Message Center This Center will provide up to date information and announcements throughout the Congress and serve as a platform for exchanging messages between the Congress participants. The center is located on the main foyer area. Airport - City Center Transfers Delegates who already purchased airport transfers will be welcomed at the exit of the international arrivals with a board on which the ISBD 2012 logo and name of the delegate will be seen. No complimentary transfers will be provided from and to the airport. You will have to make your own way to the hotel. The average price for taxi fare from the airport to the hotel to the city center is about ~ 25.-Euros. HAVATAS shuttle buses depart every half an hour from the airport to Taksim Square. One way HAVASTAS tickets are ~7.-Euros per person. Tour & Transfer Desk There will be a Tours & Transfers Desk at the registration area where all delegates will be able to purchase departure transfers, change their current departure transfers and also purchase post-conference and daily city tours. This desk will be giving service from March 14, 2012, at 13.00 until the end of the Congress.

07.30 09.00 Starting From 13.00 to 19.30 From 07.30 - 19.00 From 07.30 - 13.00

Name Badges Upon registering you received your Congress kit in which you will find your name badge. You are kindly requesting to wear name badges during the conference. Please note that delegates without a name badge will not be allowed to enter the conference venue or sessions. Language The official language of the congress is English. Exhibition The exhibition will be open at the main foyer of the Congress Center, Istanbul Lutfi Kirdar Convention Center - ICEC. Wednesday, March 14 17.00 end of Welcome reception March 15- March 16 08.00 18.00 March 17 08.00 13.00 Accompanying Persons Program Registered accompanying persons will be able to attend the Opening Ceremony, Welcome Reception. Accompanying persons will be participate 2 daily tours as below: TOUR 01 - THE MAgNIFICENT DOMES OF ISTANBUL Thursday MARCH 15 TIME : 09:00-13:00 TOUR 02 - OTTOMANIA Friday, MARCH 16 TIME: 09:00-13:00 (All tours will depart from congress venue).

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Currency & Banking The national currency in Turkey is Turkish Liras (TL). 1.-EURO = 2,35 TL / 1.-USD = 1,78 TL Banks can exchange foreign currency and travelers checks with your passport as proof of identity. Commissions are charged at between 1-3 % per transaction. Exchange rates change daily and can be checked in the press. Also Euro can be found and easily can be changed in the exchange offices. Banks are usually open between 09:00 - 12:00 and 13:30 - 17:00 on weekdays. The big retail banks all have ATMs, some of them give cash advances against foreign credit cards. Communication If you have a GSM-standard phone capable of operating on the 900MHz and/or 1800MHz band(s), you may be able to use international roaming in Turkey for at least a few weeks. For longer use, youll have to register your phone with the Turkish government Electricity The electric current is 220V AC with a frequency of 50 Hertz. European standard plugs Type C (European 2-pin) with two round pins are used. 110V AC is also found in some 5 star hotels. Congress Secretariat If you have any concerns regarding any request for the Congress please contact Kenes Turkey or visit information desk located on the ground level of the Istanbul Convention Centre. Kenes Turkey is the official Congress Organizer of The ISBD 2012 Sar Asma Sok. No 9 Yeniky, Saryer, Istanbul Tel : +90 212 299 9984 Fax : +90 212 299 9977 Email : isbd@kenes.com Site : www.kenes.com

LIST OF CONgRESS HOTELS


All Hotels in the list below are in walking distance. All hotel accommodations are included breakfast and VAT. Official check-in time for the hotels is 14.00 hours and check-out is 12:00 noon. All extra expenses such as meals, mini bar, telephone calls, dry cleaning etc. should be paid to the hotels directly before check-out.

Hilton Istanbul Hotel Cumhuriyet Cad. 34367 Harbiye Tel : 90 (212) 326 71 00 grand Hyatt Istanbul Hotel Taskisla Caddesi, Taksim, 34437 Tel : 90 (212) 368 1234 Ramada Plaza Istanbul Halaskargazi Cad. No:63 34373 Sisli Tel : 90 (212) 315 44 44 Konak Hotel Cumhuriyet Cad. No:75 34437 Elmadag Taksim Tel : 90 (212) 225 82 50 Larespark Hotel Topu Caddesi,No.23 Taksim Tel : 90 (212) 313 51 00

Nippon Hotel Topu Caddesi No:6 34437 Taksim Tel : 90 (212) 313 33 00 Titanic Hotel Lamartin Cad No 47 Taksim 34437 Tel : 90 (212) 238 90 90 Midtown Hotel Lamartin Cad No13 Taksim 34437 Beyolu, Taksim Tel : 90 (212) 361 6767 greenpark Hotel Taksim Caddesi No:79/A 34437 Taksim Tel : 90 (212) 238 9111

Madison Hotel Receppasa Caddesi No. 15, 34437 Beyoglu, Taksim 90 (212) 238 54 60 Feronya Hotel Abdlhakhamit cad.no.58 Taksim 34437 Tel : 90 (212) 238 09 01 Cartoon Hotel Beyolu Tarlaba Bulv. 36 Taksim Tel : 90 (212) 238 93 28 City Center Hotel Katip Celebi Mah. Billurcu Sokak No:1 Siraselviler Taksim Tel : 90 (212) 292 27 71

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

INFORMATION TO PRESENTERS
gUIDELINES FOR ORAL PRESENTATION
1. DISCLOSURE A disclosure slide is required for each oral presentation being given for satellite programs and for the main scientific program. The slide should address any relevant financial or other relationships you may have with commercial entities with an interest in the subject matter of your presentation. The ISBD Scientific Committee requires all Speakers to disclose any advisory or consultancy roles in the Biomedical Industry during the past 2 years on a PowerPoint slide to be shown immediately at the beginning of the presentation. Other potential conflicts of interest to be reported include: grants, honoraria, shares, paid positions on advisory boards, etc.

gUIDELINES FOR POSTER PRESENTATION


1. DISCLOSURE ISBD requests poster presenters to disclose potential conflicts of interest, regarding their current poster presentation at the bottom of their poster. This disclosure will allow the audience to take potential conflicts of interest into account when assessing the objectivity of the presentation. Potential conflicts of interest can involve: grants, honoraria, shares, paid positions on advisory boards, etc. If an author has nothing to disclose, this should also be mentioned as There are no relevant conflicts of interest to disclose at the bottom of the poster.

2. gUIDELINES All speakers giving a presentation are requested to load their presentation in the Speaker Ready Room at least two hours before your session starts or the day earlier. Presentations received after this deadline cannot be guaranteed optimal audiovisual support. Experienced and skilled technicians will assist you to transfer and check/correct your presentation. Please show up 10 minutes prior to the start of the session, identify yourself to the session Chair(s). Please remember, you are not allowed to connect your own computer to the projector. Projectors for overhead viewgraphs are not available. It is strongly recommended that speakers plan on a 15-20 minute presentation to allow for questions depending on session duration. The computer driving the display will be a PC (no Macs will be available). If you are a Mac-user, make sure that you check-in early with the Speaker Support Centre for your Mac-presentation to be converted to a pc format. PPT, PPTX, PDF, DOC, DOCX file types are accepted for the presentations. If you are going to use other file types please contact the secretariat. You should also make sure that any and all graphics, multimedia, or other files used by your presentation are included with your presentation. We kindly ask you to bring your files in a USB flash memory or in a CD. Please use large fonts so they can be read without major effort. The presentations are not stored and are deleted after the meeting.

2. PRESENTATION Please post your material at mentioned day of presentation, and take it off at the end of the poster session, leaving the pushpins on the board. Material not removed will be destroyed. One of the authors of each poster paper has to be present to answer questions for the entire duration of the poster session. Secretariat is not able to provide a printing service. Please bring your printed posters with you. Staff will be on the floor at all times to assist poster presenters.

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

WORKSHOPS
Workshop-1
Title: State of the Art in Diagnosing, Assessing and Treating Bipolar Disorder A Training Course to Become a Bipolar Expert Description: To provide an overview for clinicians who are new in the field of bipolar disorder, on how to diagnose, how to assess and how to treat (psychologically and pharmacologically) patients with bipolar disorder. The course will include 5 sessions of one hour each, consisting of short presentations by experts on the topics, each followed by extensive discussions and including exercises using clinical case vignettes, to ensure much interaction with the course participants. Chair Date & Time Full Day Room : Dr. Willem A Nolen, the Netherlands : 14 March 2012 : 09:00 - 16:00 : SULTAN 2 HALL

Workshop-3
Title: Chronotherapeutic Techniques in the Management of Bipolar Disorder Description: The acute, pharmacologic treatment of manic and depressive mood states often fails to achieve quick, complete, lasting and safe remissions. Chronotherapeutic interventions which act by shifting circadian rhythms and sleep, can produce rapid and sustained reductions in affective symptoms. In this workshop, early-career and more experienced clinicians will learn how to expand their therapeutic options with sleep deprivation-based approaches, bright light therapy, dawn simulation and other rhythm-shifting methods. Starting with a brief review of circadian neurobiology and sleep regulation, the workshop will provide detailed, practical information about each chronotherapeutic modality and how they can be combined successfully with pharmacologic treatments. Presentations will include case examples and encourage clinical questions and discussion. Based on the first treatment manual published for this emerging subspecialty (Wirz-Justice et al., 2009), workshop participants will acquire the practical knowledge necessary to know how and when to administer chronotherapeutic interventions in their clinical practices. Chair Date & Time Half Day Room : Dr. John gottlieb, USA : 14 March 2012 : 12:30 16:00 : SULTAN 1 HALL

Workshop-2
Title: Being A Woman With Bipolar Disorder Description: To educate the participants on the course of bipolar disorder throughout life cycle in female patients with a special focus on menstrual cycle/endocrinology/alcohol related problems; teaching ways of working with bipolar women in pregnancy planning, treatment plans and medication use in pregnancy; increase awareness for diagnosing and managing (including pharmacotherapy) bipolar disorder during post-partum period and lactation; updating the audience on the available screening and diagnostic tools for bipolar disorder in post-partum period. Chair Date & Time Half Day Room : Dr. Ayegl zerdem, Turkey : 14 March 2012 : 12:30 - 16:00 : SULTAN 3 HALL

Workshop-4
Title: Advanced Clinical Topics And Future Trends In Bipolar Disorders Description: Summarize in a comprehensive presentation the new findings and trends in neurobiology, diagnostic and clinical approaches in bipolar disorders. Discuss the staging model of treatment as a useful clinical algorithm to increase early diagnosis and treatment. Understand the biological markers related to bipolar disorders and its clinical correlation. Review the proposed changes for DSM 5, regarding the mixed episode criteria, and study the new concepts of course specifiers and subsyndromal states. Analyze the dilemma of using antidepressants in bipolar population and the possible consequences they may generate in the course and characteristics of future episodes of the disorder. Review the new medications that may follow the current pharmacological options for treatment and underline the future research projects, and clinical areas of opportunity for new findings in bipolar disorders. Chair Date & Time Half Day Room : Dr. Manuel Sanchez Carmona, Mexico : 14 March 2012 : 08:30 - 12:00 : SULTAN 1 HALL

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

FLOOR PLANS

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

ICEC LEVEL 1

ICEC LEVEL 2

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

ICEC gROUND LEVEL

ICEC LOWER LEVEL

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

ICEC OVERVIEW

EXHIBITON PLAN

@ internet cafe

1 2 3 4

CINP LILLY ILAC 11TH WORLD CONGRESS OF BIOLOGICAL PSYCHIATRY MUSTAFA NEVZAT

5 6 7 8

ISBD - INTERNATONAL SOCIETY FOR BIPOLAR DISORDERS LITHIUM SOCIETY TURKEY BIPOLAR LIFE ASSOCIATION TURKEY BIPOLAR DISORDERS SOCIETY TURKEY

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

COMPANY PROFILES
LUNDBECK

SPONSORS

SPONSORS
ASTRA ZENECA AstraZeneca Alderley House, Alderley Park, Macclesfield, Cheshire UK AstraZeneca is a global, innovation-driven biopharmaceutical business with a primary focus on the discovery, development and commercialisation of prescription medicines for gastrointestinal, cardiovascular, neuroscience, respiratory and inflammation, oncology and infectious disease. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information please visit: www.astrazeneca.com

H. Lundbeck A/S Otilliavej 9 DK-2500 Valby Copenhagen Denmark Tel: +45 36 30 13 11 www.lundbeck.com Lundbeck The Specialist in Psychiatry Pioneer in Neurology H. Lundbeck A/S is an international pharmaceutical company truly dedicated and focused in research & development, production, marketing and sales of medicines for diseases within CNS. The company has a long history of creating innovative treatments for depression and anxiety. Cipralex/Lexapro (escitalopram) has confirmed the leading position in this area. Today, more than 200 million patients have been treated with Cipralex/Lexapro. Lundbeck also markets Ebixa (memantine) for treatment of Alzheimers disease and Azilect (rasagiline) for treatment of Parkinsons disease. Lundbeck is currently launching Sycrest (asenapine) in the EU for treatment of bipolar disorder. Furthermore, in the coming year, Lundbeck is expecting to launch Selincro (nalmefene) for the treatment of Alcohol disorders. JANSSEN RESEARCH & DEVELOPMENT, L.L.C. At Janssen Research & Development, LLC, we are united and energized by one mission to discover and develop innovative medicines that ease patients suffering, and solve the most important unmet medical needs of our time. As one of the Janssen Pharmaceutical Companies, our strategy is to identify the biggest unmet medical needs and match them with the best science, internal or external, to find solutions for patients worldwide. We leverage our world-class discovery and development expertise, and operational excellence, to bring innovative, effective treatments in five therapeutic areas: cardiovascular and metabolism, immunology, infectious diseases and vaccines, neuroscience, and oncology. We think of the world as our laboratory and we look for innovation wherever it exists. This drives our relentless search for the best science, and our pursuit of collaborations and partnerships. We believe there are no limits to what science can do. And we never lose sight of those who rely most on our discoveries. For more information, visit www.janssenrnd.com . PFIZER Pfizer lalar Ltd. ti. Muallim Naci Cad. No: 55 34347 Ortakoy /IST Pfizer Turkey has been providing services to Turkish medicine and society with its products and activities since 1957. The company has been continuously contributing to the development of medicine and working for a healthier life through scientific and educational programs, clinical researches and scholarships. Pfizer uses science and its resources worldwide to contribute to health and quality life in every stage of life, and offers its explored, innovative health products to the service of medicine. Biological products, small-molecule drugs and vaccines as well as nutrition and consumer products are included in the wide range of Pfizer products for numerous areas of health and animal health. www.pfizer.com.tr

BRISTOL-MYERS SQUIBB & OTSUKA PHARMACEUTICALS EUROPE LTD Bristol-Myers Squibb Pharmaceuticals 3 rue Joseph Monier 92500 Rueil Malmaison France Bristol-Myers Squibb (BMS) is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. Around the world, our medicines help millions of people in their fight against cancer, cardiovascular disease, diabetes, hepatitis B, HIV/AIDS, rheumatoid arthritis and psychiatric disorders. Otsuka Pharmaceuticals Europe Ltd 1, rue Eugne et Armand Peugeot 92508 Rueil-Malmaison Cedex France Otsuka has a passion for improving the health of people worldwide. We are committed to focusing our research and development on innovative products that address unmet medical needs. Otsukas European sales and marketing operations are based in France, Germany, Italy, the Nordics, Spain and the UK.

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

SPONSORS
EgE ENDUSTRI Ege Endustri A.S. Kemalpasa Caddesi No:18, 35060 Pinarbasi, Izmir, Turkiye P: 0090 232 4911400 F: 0090 232 4790468 Ege Endustri, founded in 1974 and based in Izmir Turkey has professionalized on designing, manufacturing and testing of fabricated axles, axle components, axle beams, axle housings and suspension parts for light to heavy duty on and off road truck / bus applications. The company is %64 owned by Bayraktar Holding and %36 open to public. With two facilities and a total of 600 personnel working at Pinarbasi and Gaziemir Free Zone, Ege Endustri supplies products to Scania, MAN (Trucknology award winner 2009), Daimler, Meritor, Sisu Axles, Axle Tech, Hendrickson and American Axle in multiple locations in Americas, Europe and Asia. The total export figure for 2011 is $ 80,000 which makes up to % 80 of the sales.

EXHIBITORS
CINP (THE INTERNATIONAL COLLEgE OF NEUROPSYCHOPHARMACOLOgY) CINP Central Office Braeview House 9-11 Braeview Place East Kilbride Scotland UK G74 3XH CINP is the worlds only global organisation dedicated to neuropsychopharmacology. CINP was established in 1957 in Zurich and had its first international congress in Rome in 1958. It is a membership organisation with widespread support from all over the world. CINPs mission is to encourage and promote the international scientific study, teaching and application of neuropsychopharmacology. It provides consultation for the better evaluation of all aspects of development and usage of neuropsychiatric drugs, including their biochemistry, pharmacology, safety and therapeutic efficacy. Through these activities CINP seeks to improve and advance research activities to lead to improved patient care.

EgE FREN Ege Fren Sanayi ve Ticaret A.. 7405/2 Sokak No.4 Pnarba Izmir Ege Fren Sanayi ve Ticaret A., have been established on January 21st 1987 by Otomobilcilik A.. (%51) an affiliate of zakat Holding, and Rockwell International Finance Co. (%49) Shares of domestic shareholder (%51) have been transferred to Hseyin Bayraktar Yatrm Holding in 1990, and foreign shareholder (%49) to Meritor Automative GmbH on 1997. Paid capital of the company is 8,000,000 TL at the end of 2004. Main plant, located in Pnarba-zmir covers 8,500 sqms on an area of 14,500 sqms, while the 2. plant producing fo export covers 6,200 sqms is Aegean Free Zone at Gaziemir-zmir.

ISBD ISBD - International Society for Bipolar Disorders 4601 Baum Blvd, 1st floor Pittsburgh, PA 15213-0168 USA ISBD is a global network of individuals dedicated to finding ways to improve the lives of those with bipolar disorder through collaboration, research, and education. In addition to individual members, the ISBD has a global chapter network of like-minded organizations formed to meet the unique challenges of treating bipolar disorder in their country/region. As an international organization, ISBD offers networking and collaborative opportunities globally, discounts to ISBDs Conferences, mentorship and award opportunities for residents, fellows and junior faculty, and access to our online membership directory, quarterly newsletter, and other benefits.

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

EXHIBITORS
MUSTAFA NEVZAT PHARMACEUTICAL INDUSTRIES, INC. Pak Is Merkezi Prof. Dr. Blent Tarcan Sok. No 5/1 34349 Gayrettepe - ISTANBUL - TURKEY Tel: (212) 337 3800 Fax: (212) 337 3801 E-mail: info@mn.com.tr Mustafa Nevzat pharmaceuticals, the national pharmaceutical industry in business since 1923, the most established pharmaceutical companies. Turkish pharmaceutical industry has taken many first signature and national pharmaceutical industry company is a pioneer in the development of the contribution. Mustafa Nevzat, expert staff and FDA, EMEA today 1400 persons, approved by the authorities, such as raw-material production including allS MHRA manufacturing facilities with Turkeys leading manufacturers of finished medicines and pharmaceutical raw materials. Mustafa Nevzat Drug as our mission; our country and the world people to qualify for a healthier and happier life-quality, reliable and cost-effective products to our users

EXHIBITORS
BIPOLAR DISORDERS ASSOCIATION OF TURKEY Simavi Vahip, M.D., Prof. Ege University School of Medicine Department of Psychiatry Affective Disorders Unit Bornova 35100 zmir Bipolar Disorders Association of Turkey is one of the oldest chapters of International Society for Bipolar Disorders (ISBD). The association was founded in 2007 by a group of mental health professionals. The aims of the association are to increase awareness in the community on the cause, course and treatment of bipolar disorders, to facilitate fight against stigmatization and alienation of the patients, to contribute to health policy making processes that are pertinent to chronic mental illnesses including bipolar disorder; to support scientific research and educational programs for professionals. Up to date, the association supported research projects, ran an educational summer school for young clinicians, contributed to the treatment guidelines of bipolar disorder in collaboration with Psychiatric Association of Turkey, and provided educational grant for 50 residents for conference participation.

LILLY Kubak Caddesi Rainbow Plaza No: 4 Kat: 1 Altunizade - ST Founded by Eli Lilly in 1876, Indianapolis USA, Eli Lilly and Company is the 10th largest pharmaceutical company in the world. With its close to 40,000 employees worldwide, Lilly makes medicines that help people live longer, healthier, more active lives. Today, Lilly has manufacturing plants located in 13 countries and R&D facilities in 8 countries. Its products are marketed in 125 countries. Since the 1950s, where its products were first distributed in the Turkish market, Lillys mission in Turkey was to improve outcomes for individual patients by accelerating the flow of innovative medicines. Founded in 1993, Lilly la brings innovative treatments to patients in the therapeutic areas of CNS (central nervous system), diabetes, endocrinology, oncology, erectile dysfunction, cardiology and osteoporosis. www.lilly.com.tr

LITHIUM SOCIETY TURKEY Lithium Society is the first advocacy oriented body in Turkey, founded by a small group of patients and psychiatrists in Izmir in 1997. It has nearly 75 members consisted mainly by patients and family members. The societys name is a tribute to lithium, the widely known life saving molecule. The aims of the society are to increase awareness for early diagnosis and treatment of bipolar disorder, provide support for patients and families, and to fight against stigmatization. Lithium society operated locally in Izmir since its establishment with support group meetings for the patients, periodic educational lectures and social activities open to the public. Lithium Club is the artistic arm of the society where patients get together for painting sessions. It has provided a therapeutic environment to many individuals who were otherwise confined to indoors due to adversities of a long lasting course of illness. The strength of the society is the contributions coming from volunteers. However the weak coherence among the members and inefficient financial support have been the major challenges of the society over the years. www.lityumdernegi.gen.tr.tc

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

EXHIBITORS
BIPOLAR LIFE ASSOCIATION (BLA), TURKEY www.bipolaryasam.org Bipolar Life Association is a voluntary patient and family organization that incepted in 2007 in Istanbul. A group of psychiatrist, psychologist, nurse, patients and families came together and to educate the community about bipolar disorders. The association focuses on support, education, bring the patients and professional together to help individuals and families affected by bipolar disorders. Most activities continue on web page and with some educational meetings that gathering professionals, patient and families. One of the targets is also build a bridge between patients and specialized mood disorders clinics.

11th WORLD CONgRESS OF BIOLOgICAL PSYCHIATRY 23-27 June 2013 www.wfsbp-congress.org

SCIENTIFIC PROGRAM

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

ISBD 2012 SCIENTIFIC PROgRAM


Day 1: Wednesday, March 14, 2012
08:30 16:00 13:00 19:00 16:00 - 17:00 17:00 - 18:00 Workshops Registration ISBD Membership Meeting OPENINg CEREMONY Welcome Address: Aysegul Ozerdem Turkish psychiatry Achievements and Challenges Presidential Welcome: Mauricio Tohen Important updates since 2010 meeting Awards Presentation: Gershon Awards by M. Tohen, W. nolen Sponsored by Lundbeck 18:00-19:30 Cocktail Reception and Buffet DoLMABAHCE C HALL AnADoLu AuDToruM 08:00 09:00 KEYNOTE 1

Day 2: Thursday, March 15, 2012


ANADOLU AUDITORIUM

Childhood Bipolar Debate Moderators: Eric Youngstrom, University of North Carolina, USA Michael Wong, Queen Mary Hospital, Hong Kong, Hong Kong S.A.R What is pediatric bipolar disorder? Boris Birmaher, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania What is pediatric bipolar disorder? Eric Taylor, Kings College London, UK QUESTION & ANSWERS 09:00 10.00 CORE SYMPOSIUM 1 Optimizing Functional Outcomes in BD Chair: Eduard Vieta, University of Barcelona, Spain Lifestyle factors in optimizing therapeutic outcomes Michael Berk, Barwon Health Swanston Centre, Australia Psychoeducation in Bipolar patients Francesc Colom, Institute of Neurosciences, Hospital Clinic, University of Barcelona, Spain Functional remediation for bipolar disorder Eduard Vieta, University of Barcelona, Spain QUESTION & ANSWERS 10:00 10:15 Coffee Break ANADOLU AUDITORIUM

Welcome Reception will be organized at the main foyer of the Anadolu Auditorium at ICEC. 19:30-21:00 EVENINg SYMPOSIUM
Sponsored by BMS/OTSUKA

ANADOLU AUDITORIUM

Long-term success in preventing recurrence of mood events in bipolar disorder Chair: Heinz grunze Introduction and Welcome: Heinz grunze, UK Is Switching Antipsychotic Medications in Stable Patients Ever a good Idea? Christoph Correll, USA Choosing Long-term Treatment in Bipolar I Disorder on the Basis of Predominant Polarity Eduard Vieta, Spain Q&A Heinz Grunze Assessing the Evidence for Maintenance Treatment in Bipolar I Disorder: The Impact of Clinical Trial Design Michael gitlin, USA Q&A Heinz Grunze Assessing the Evidence when Creating guidelines for Maintenance Treatment in Bipolar I Disorder: What Do We Know and What Dont We Know? Heinz grunze, UK Q&A Session All faculty Summary and Meeting Close Heinz Grunze

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Day 2: Thursday, March 15, 2012


10:15 11:15 CORE SYMPOSIUM 2 ANADOLU AUDITORIUM 13:45 14:15 KEYNOTE 2

Day 2: Thursday, March 15, 2012


ANADOLU AUDITORIUM

Interpreting clinical trials in bipolar disorder/methodological issues in clinical trials in bipolar disorder Chair: Olcay Yazici, University of Istanbul, Istanbul Medical School, Istanbul, Turkey Design of Clinical Trials in bipolar disorders Mauricio Tohen, University of Texas, USA Lithium and Anticonvulsant Mood Stabilizers Lamotrigine and Divalproex for Bipolar Depression Joseph Calabrese, Case Western Reserve University, USA QUESTION & ANSWERS 11.15 11:45 Break 11:45 13:15 SATELLITE SYMPOSIUM
Sponsored by ASTRA ZENECA

Updates from the NIMH Chair: Willem A. Nolen, University Medical Center Groningen, The Netherlands A Translational Perspective in the Search for Improved Treatments for Bipolar Disorder Carlos Zarate, National Institute of Mental Health, Maryland, USA QUESTION & ANSWERS 14:15 15:45 CONCURRENT SESSIONS I 14:15 15:45 SYMPOSIUM 1 MARMARA HALL

ANADOLU AUDITORIUM

Efficacy versus pragmatic effectiveness trials in the long-term treatment of bipolar disorder. Chair: Willem A Nolen, University Medical Center Groningen, The Netherlands Efficacy vs pragmatic effectiveness trials in the long-term treatment of bipolar disorder: the valproate story Andrea Cipriani, University of Verona, Italia Efficacy vs. pragmatic effectiveness trials in the long-term treatment of bipolar disorder: the lamotrigine story Rasmus W Licht, Aarhus University Hospital, Risskov, Denmark Efficacy versus pragmatic effectiveness trials in the long-term treatment of bipolar disorder: The lithium story Willem A Nolen, University Medical Center Groningen, The Netherlands Efficacy versus pragmatic effectiveness trials - The antipsychotic story Joseph R Calabrese, Case Western Reserve University, USA QUESTION & ANSWERS

A Journey from Pole to Pole: Todays Challenging Patient Chair: Mauricio Tohen Welcome and introduction A complex diagnosis Timucin Oral, Turkey The challenges of acute treatment Eduard Vieta, Spain The challenge of long-term treatment: complexities and comorbidities Roger McIntyre, Canada QUESTION & ANSWERS 13:15 13:45 Lunch Break

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Day 2: Thursday, March 15, 2012


14:15 15:45 SYMPOSIUM 2 TOPKAPI A HALL

Day 2: Thursday, March 15, 2012


14:15 15:45 SPECIAL SESSION Samuel gershon Awards for Junior Investigators Sponsored by LUNDBECK Chair: Simavi Vahip, Ege University Medicine Faculty, Turkey Neural Activity During Emotion Processing in Bipolar versus Unipolar Depression in Adolescents RS Diler, ML Phillips, B Birmaher, C Ladouceur, J Almeida, D Axelson Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA, US Executive function deficits and morphological brain changes in patients with bipolar I disorder following recovery from a first manic episode J Kozickya, TH Haa,b, IJ Torresa,c, DJ Bonda, RW Lama, LN Yathama a Department of Psychiatry, University of British Columbia, Vancouver, BC Canada, b Department of Psychiatry, Seoul National University Bundang Hospital, Korea, c Research Department, Riverview Hospital, British Columbia Mental Health and Addictions Services, Coquitlam, BC Canada A nested population-based case-control study on peripheral inflammation markers and brain-derived neurotrophic factor in early-stage mood disorders PV Magalhesa, K Jansenb, RT Pinheirob, gR Friesa, AL Teixeirac, RA da Silvab, F Kapczinskia a National Institute for Translational Medicine, Hospital de Clnicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; bPrograma de Ps-Graduao em Sade e Comportamento, Universidade Catlica de Pelotas, Brazil; cLaboratory of Immunopharmacology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil Brain-Derived Neurotrophic Factor in Juvenile Bipolar Disorder and AttentionDeficit Hyperactivity Disorder: differentiation using BDNF serum levels, and Val66Met polymorphism CP Zeni, S Tramontina, BW Aguiar, A Salatino-Oliveira, gF Pheula, M Hutz, FP Kapczinski, LA Rohde Federal University of Rio Grande do Sul, Brazil QUESTION & ANSWERS DOLMABAHCE C HALL

Molecular biology of mitochondrial dysfunction: implication and novel findings in Bipolar disorder Chairs: Trevor Young, University of Toronto, Canada Michael Berk, Barwon Health Swanston Centre, Australia Neural basis of behavioral phenotypes of mice with neuron specific accumulation of mtDNA mutations Tadafumi Kato, RIKEN Brain Science Institute, Wako, Saitama, Japan Synaptosomal-associated protein 25 and Oxidative Damage in bipolar disorder Ana Cristina Andreazza, University of Toronto, Canada. Novel therapeutics opportunities for bipolar disorder: New research data Michael Berk, Barwon Health Swanston Centre, Australia A multi-disciplinary approach to studying mitochondrial abnormalities in bipolar disorder Dost Ongur, Bruce Cohen, McLean Hospital/Harvard Medical School, USA QUESTION & ANSWERS

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Day 2: Thursday, March 15, 2012


14:15 15:45 PARALLEL 1 TOPKAPI B HALL

Day 2: Thursday, March 15, 2012


16:00 17: 30 SYMPOSIUM 4 TOPKAPI A HALL

Multiple Co-morbidities in bipolar disorder: diagnostic and treatment challenges Chair: Ihsan Salloum, University of Miami, USA Optimizing treatment outcome for bipolar disorder with comorbid addictive disorders Ihsan Salloum, University of Miami, USA Impulse control disorders comorbidity in bipolar disorder Lut Tamam, Cukurova University Faculty of Medicine, Turkey The Journey of Addiction in Bipolar Disorder Mark Frye, Mayo Clinic, USA QUESTION & ANSWERS 15:45 16:00 Coffee Break 16:00 17: 30 CONCURRENT SESSIONS II 16:00 17: 30 SYMPOSIUM 3 Modern Clinical Management of Bipolar Disorder Chairs: gin S Malhi, University of Sydney, Australia Mark Frye, Mayo Clinic, USA Treatment of Mania and Mixed States Roger McIntyre, University of Toronto, Canada Treatment Options for Acute Depression in Bipolar Disorder Michael Bauer, Technische Universitt Dresden, Germany Maintenance Treatments in Bipolar Disorder Michael gitlin, Geffen School of Medicine at UCLA, USA The treatment of Complex Bipolar Disorder gin Malhi, University of Sydney, Australia QUESTION & ANSWERS MARMARA HALL

Development and determinants of psychopathology in prospective bipolar offspring cohorts Chairs: Manon Hillegers, Universitair Medisch Centrum Utrecht, the Netherland Ketil J. Oedegaard, Haukeland University Hospital, Norway The Pittsburgh Bipolar Offspring Study Boris Birmaher, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania Attachment, Temperament, and Cortisol Profiles in the offspring of bipolar parents Sarah Doucette, Dalhousie University, Canada, Predictors of the longitudinal course of mood disorders in children and adolescents Martin Preisig, University Hospital Center and University of Lausanne, Switzerland Prevalence and course of psychopathology in a prospective Dutch bipolar offspring cohort - A 12 year follow-up Manon Hillegers, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands QUESTION & ANSWERS

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Day 2: Thursday, March 15, 2012


16:00 17: 30 BREAKINg NEWS 1 DOLMABAHCE C HALL

Day 2: Thursday, March 15, 2012


Suicidal behaviors in bipolar children: A community-based multisite investigation RC Castilla-Puentesa, WI Castilla-Puentesb, SR Castilla-Puentesc, IS Lopezd, A Camachoe, ME Habeychf , CA Sanchez-Russig a Departments of Psychiatry, Epidemiology and Pharmacoepidemiology, at the School of Medicine, UNC and at the School of Pharmacy, QA/RA, Temple University, Philadelphia, PA, bDepartment of Obstetrics and Gynecology, Hospital Regional, Duitama, Boyaca, Colombia, cDepartment of Anesthesiology, Hospital Regional, Duitama, Boyaca, Colombia, dDepartments of Psychiatry, Hospital San Rafael,San Rafael, Mendoza, Argentina, eDepartment of Psychiatry, University of California, San Diego; Sun Valley Behavioral & Research Center, CA, fCenter for Clinical Neurophysiology, University of Pittsburgh, Pittsbrugh, PA, gDepartment of Epidemiology and Public Health, INSA-Colombia, Boyaca, Colombia The Illness Cognitions Scale: A new scale to measure maladaptive illness beliefs and behaviors that may impede recovery S Dodda,b, M Berka,b,c,d, L Berkb, PB Fitzgeralde, AR de Castellae, S Filiae, K Filiae, AJM Brnabicf, K Kelinf, W Montgomeryf, J Kulkarnie, L Staffordb,g a School of Medicine, Deakin University, Geelong, Australia, bDepartment of Psychiatry, University of Melbourne, Parkville, Australia, cOrygen Research Centre, Parkville, Australia, dMental Health Research Institute, Parkville, Australia, e Alfred Psychiatry Research Centre, The Alfred and Monash University, School of Psychology, Psychiatry and Psychological Medicine, Commercial Road, Melbourne, Australia, fEli Lilly Australia Pty Ltd, Sydney, Australia, gCentre for Womens Mental Health, Royal Womens Hospital, Parkville, Australia QUESTION & ANSWERS

BREAKINg NEWS 1 (Oral Presentations) Chair: gustavo Vazquez, University of Palermo, Buenos Aires, Argentina The effect of lithium and age on brain volume in patients with bipolar disorder L Abramovic, NEM van Haren, MPM Boks, F Bootsman, HG Schnack, R Brouwer, HE Hulshoff Pol, RS Kahn Psychiatry department, University Medical Centre Utrecht, Utrecht, The Netherlands Impact of first-episode polarity on clinical features associated to suicide attempts in bipolar disorder type I patients LN Abreua, FG Nerya, AM Scippab, F Kapczinskic, B Lafera. a Bipolar Disorder Research Program, Institute of Psychiatry, University of So Paulo School of Medicine, So Paulo, Brazil, bTeaching Hospital-Psychiatry Service, Federal University of Bahia, Salvador, Brazil, cBipolar Disorder Program, Department Of Psychiatry, Federal University of Rio Grande do Sul, National Institute for Science and technology- Translational Medicine, Porto Alegre, Brazil Towards an assessment tool for mixed depression: a multinational study using modified Hypomania Checklist (mHCL) in bipolar and unipolar depression K Altinbasa, A Ozerdemb,c N Yalinb, Z Ersoyb, O Aydemird, M Prietoe, S Oztekind, E Aydind, M Fuentesf, S Feederf, MA Fryef a RaitTahsin Mood Clinic, Bakrky Research and Training Hospital for Psychiatry, Neurology and Neurosurgery,Istanbul,Turkey, bDepartment of Psychiatry, Faculty of Medicine, Dokuz Eylul University, Izmir,Turkey, cDepartment of Neuroscience, Health Sciences Institute; Dokuz Eylul University, Izmir,Turkey, dDepartment of Psychiatry, Faculty of Medicine, Celal Bayar University, Manisa, Turkey, e Department of Psychiatry, University of Los Andes, Santiago, Chile f Department of Psychiatry, Mayo Clinic, Rochester, MN, USA Monozygotic twins discordant for bipolar disorder show functional DNA methylation changes in whole blood and brain. MPM Boksa,b, R Pidsleyc, K van Eijkd, EL Dempsterc, S de Jonge, L Schalkwijkc, HE Hulshof-Polla, NEM van Harena, R Murrayc, RS Kahna, J Millc, RA Ophoffa,d a Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands bJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands, cInstitute of Psychiatry, Kings College London, United Kingdom, d Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands, eUCLA Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Day 2: Thursday, March 15, 2012


16:00 17: 30 PARALLEL 2 TOPKAPI B HALL

Day 3: Friday, March 16, 2012


08:00 09:30 CORE SYMPOSIUM 3 ANADOLU AUDITORIUM

ISBD Womens Health Task Force Chairs: Aysegul Ozerdem, Dokuz Eylul University Medical School, Turkey Danilo Quiroz, Mood and Anxiety Center Efeso, Santiago, CHILI Women are more vulnerable for Thyroid function abnormality in bipolar disorder Aysegul Ozerdem, Dokuz Eylul University Medical School, Turkey How to be a Mother: Pregnancy and Breastfeeding Planning for Women with Bipolar Disorder Fisun Akdeniz, Ege University School of Medicine, Turkey Childbirth and bipolar disorder: challenges and opportunities Verinder Sharma, University of Western Ontario, Canada Brain derived neurotrophic factor in women with bipolar disorder compared to controls Natalie Rasgon, Stanford University School of Medicine, USA QUESTION & ANSWERS 17:30 19:00 POSTER SESSION I 17:30 20:30 TURKISH ADVOCACY FORUM 19:00 20:30 EVENINg SYMPOSIUM FOYER - 1 ST FLOOR MARMARA HALL ANADOLU AUDITORIUM

Special Session on DSM-5 (ICD) Updates: Focus on Bipolar Chair: David Kupfer Update on Diagnostic Criteria for Bipolar Disorder David Kupfer, University of Pittsburgh School of Medicine, USA The DSM-5 field trials and bipolar disorders Ellen Frank, University of Pittsburgh School of Medicine, USA 09:30 10.30 KEYNOTE 3 Bipolar Spectrum Chair: gary Sachs, Massachusetts General Hospital, USA The Bipolar Spectrum: From temperament to genes Hagop Akiskal, San Diego Veterans Administration Medical Center,Psychiatry Service, USA QUESTION & ANSWERS 10:30 10:45 Coffee Break ANADOLU AUDITORIUM

(Language: Turkish / No translation available)

10: 45 12.15 CORE SYMPOSIUM 4

ANADOLU AUDITORIUM

Sponsored by ASTRA ZENECA

From Pole to Pole: Travelling to the Future Chair: Joseph Calabrese Welcome and introduction The neurobiology of affective disorders Ali Saffet gonul, Turkey Developments in pharmacotherapy for depressive symptoms Lakshmi Yatham, Canada Beyond pharmacotherapy Francesc Colom, Spain Panel discussion Summary and close All Chair

Molecular genetics Chairs: Charlie Nemeroff, University of Miami, USA Luis Madrid Peroza, Centro Clnico Profesional Caracas, Venezuela Individual differences and evidence based psychopharmacology Robert Belmaker, Ben-Gurion University of the Negev, Israel genetic Research into Bipolar Disorder Marcella Rietschel; Heidelberg University/Medical Faculty Mannheim, Germany Prediction of Disease Vulnerability and Treatment Response in Mood Disorders: Personalized Medicine in Psychiatry Charlie Nemeroff, University of Miami, USA QUESTION & ANSWERS 12:15 12:45 Lunch Break

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Day 3: Friday, March 16, 2012


12:45 14:15 SATELLITE SYMPOSIUM
Sponsored by LUNDBECK

Day 3: Friday, March 16, 2012


ANADOLU AUDITORIUM 14:15 15:45 SYMPOSIUM 6 TOPKAPI A HALL

Time to revisit the definition and treatment of bipolar I disorder in a Multidimensional way Chair: Michael Berk, Australia Introduction By Michael Berk, Australia The complexity of subsyndromal symptoms in the management of bipolar I disorder Michael Berk, Australia Asenapine and its multifunctional receptor profile: differentiation and clinical relevance Mohammed Shahid, UK Effective remission with asenapine treatment in patients with bipolar I disorder Andrea Fagiolini, Italy Panel discussion QUESTION & ANSWERS 14:15 15:45 CONCURRENT SESSIONS III 14:15 15:45 SYMPOSIUM 5 MARMARA HALL

Functional Consequences of Risk genes for Bipolar Disorder Chairs: Carrie Bearden, University of California, Los Angeles, USA Carlos Lopez, Hospital Universitario San Vicente de Paul, Colombia The effect of CACNA1C rs1006737 polymorphism on brain structure, function and connectivity in BD Sophia Frangou, Kings College London, UK Delineating the genetic Architecture of Bipolar Disorder with Neurocognitive, Neuroimaging and Transcriptional Endophenotypes David glahn, Hartford Hospital, Yale University Bipolar Endophenotypes in a genetically Isolated Population Carrie Bearden, University of California, Los Angeles, USA QUESTION & ANSWERS 14:15 15:45 BREAKINg NEWS 2 DOLMABAHCE C HALL

(Oral Presentations) Chair: Yeon Ho Joo, University Of Ulsan College Of Medicine, South Korea Sensitivity and specificity of the Mood Disorders Questionnaire as a screening for bipolar disorder during pregnancy and postpartum BN Freya,b,c, W Simpsona,c, L Wright d, M Steinera,c a Womens Health Concerns Clinic, St. Josephs Healthcare Hamilton; bMood Disorders Program, Department of Psychiatry and Behavioural Neurosciences, McMaster University; cMiNDS Neuroscience Program, McMaster University; dPsychology Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada The effect of emotion regulation on cortico-limbic coupling in bipolar disorder and schizophrenia RW Morrisa,b, A Sparksa,c, PB Mitchella,c, C Shannon Weickerta,b,d, MJ Greena,b,c. a School of Psychiatry, University of New South Wales, Randwick, NSW, Australia; b Schizophrenia Research Institute, Darlinghurst, NSW, Australia; cBlack Dog Institute, Prince of Wales Hospital, Randwick, NSW, Australia; dSchizophrenia Research Laboratory, Neuroscience Research Australia, Randwick, NSW, Australia.

Psychosocial Treatments for Bipolar Disorder: Cross-Cultural Approaches Chairs: Sibel Cakir, Istanbul University, Istanbul Medical School, Turkey Eric Youngstrom, University of North Carolina, USA Cross-Cultural Insights into the Assessment and Treatment of Bipolar Disorder Eric Youngstrom, University of North Carolina, USA Psychosocial Approach to Bipolar Disorders: Developing a Culture-Specific Model Sibel Cakir, Istanbul University, Istanbul Medical School, Turkey The Effect of group Psychoeducation on the Korean Patients with Bipolar Seunghee Won, Kyungpook National University, School of Medicine, Daegu, Korea Psychosocial community approach for Bipolar Patients from Mexico Manuel Sanchez de Carmona, ISBD Mexican Chapter, Mexico QUESTION & ANSWERS

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Day 3: Friday, March 16, 2012


Childhood maltreatment and physical health problems among people with bipolar disorder gM Hosang, B Maughan, P Mcguffin, AE Farmer MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Kings College London, De Crespigny Park, London SE5 8AF, United Kingdom Personalized pharmacotherapy for bipolar disorder: genetic predictors of response to lithium JR Kelsoea,b, SG Leckbanda,c, A Demodenaa,b, M McCarthya,b, T Shekhtmana,b a Department of Psychiatry, University of California, San Diego, CA, USA, b Department of Psychiatry, VA San Diego Healthcare System, La Jolla, CA, USA, c Department of Pharmacy, VA San Diego Healthcare System, La Jolla, CA USA Aberrant set points of the immune system in a Dutch bipolar offspring cohort - twelve year follow up E Mesman, MHJ Hillegers, WA Nolenb, HA Drexhagec Department of Psychiatry, University Medical Centre Utrecht, Utrecht, The Netherlands, bDepartment of Psychiatry, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands, cDepartment of Immunology, Erasmus Medical Centre, Rotterdam, The Netherlands Reduced inferior frontal gyrus activation during emotion inhibition in young people at increased genetic risk for bipolar disorder PB Mitchella,b ,g Robertsa,b , MJ Greena,c, M Breakspeara,b,d,e, C McCormacka,b, A Franklanda,b, A Wrighta,b, F Levya,f, R Lenroota,c, HN Chana,b,g a School of Psychiatry, University of New South Wales, Randwick NSW, Australia, b Black Dog Institute, Prince of Wales Hospital, Randwick NSW, Australia, c Neuroscience Research Australia, Randwick, NSW, Australia, dDivision of Mental Health Research, Queensland Institute of Medical Research, Brisbane, Queensland, Australia, eRoyal Brisbane and Womens Hospital, Brisbane, Queensland, Australia, f Prince of Wales Hospital, Randwick, NSW, Australia, gDepartment of Psychiatry, Singapore General Hospital, Singapore. QUESTION & ANSWERS 14:15 15:45 PARALLEL 3

Day 3: Friday, March 16, 2012


TOPKAPI B HALL

Lithium Chairs: Simavi Vahip, Ege University Medicine Faculty, Turkey Oscar Heeren Ramos, Peru Lithium, still a major option in the management of bipolar disorder Rasmus Licht, Aarhus University Psychiatric Hospital, Denmark Reasons to use lithium in bipolar disorders and obstacles in real world Simavi Vahip, Ege University Medicine Faculty, Turkey Combination of Lithium with atypical Antipsychotics for long-term management of Bipolar Disorder Carlo Altamura, University of Milan, Italy QUESTION & ANSWERS 15:45 16:00 Coffee Break 16:00 17: 30 CONCURRENT SESSIONS IV 16:00 17: 30 SYMPOSIUM 7 MARMARA HALL

genomic and Clinical Phenotypic Considerations in Evaluating AntidepressantInduced Mania to Individualize the Treatment for Bipolar Depression Chairs: Mark A. Frye, Mayo Clinic, USA Shigenobu Kanba, Kyushu University, JAPAN Clinical Correlates of Antidepressant Induced Mania Robert Post, MD, USA A meta-analysis examining risk of switch following treatment with antidepressants in patients with bipolar depression glenda MacQueen, University of Calgary, Calgary, AB, Canada The Clinical Phenotype of Antidepressant-Induced Mania: Previous Methodologic Limitations and Recommendations for Future Studies Mark A. Frye, Mayo Clinic, USA Discussion Thomas g. Schulze, Gttingen Georg-August-Universit, Germany QUESTION & ANSWERS

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Day 3: Friday, March 16, 2012


16:00 17: 30 SYMPOSIUM 8 - ISAD SESSION TOPKAPI A HALL

Day 3: Friday, March 16, 2012


Treatment resistant bipolar depression: A randomized controlled trial of electroconvulsive therapy HK Schoeyena,b,k, U Kesslerb,c,k, BH Auestadd, P Bergsholme, UF Maltf,g, OA Andreasseng,h, KJ Oedegaardb,c, AE Vaaleri,j, G Morkeni,j a MoodNet Research Group, Stavanger University Hospital Stavanger, Norway, b University of Bergen, Bergen, Norway, cMoodNet Research Group, Haukeland University Hospital, Bergen, Norway, dFaculty of Science and Technology, University of Stavanger, Stavanger, Norway, ePsychiatric Clinic Frde, Frde, Norway, fDepartment of Psychosomatic Medicine and Neuropsychiatry, Oslo University Hospital, Oslo, Norway, g Institute of Clinical Medicine, University of Oslo, Oslo, Norway, hDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway, iNorwegian University of Science and Technology, Trondheim, Norway, jstmarka Department of Psychiatry, St. Olav Hospital, University Hospital of Trondheim, Trondheim, Norway, kDrs Schoeyen and Kessler contributed equally Impact of Increased Body Mass Index on Brain White Matter Integrity in First Episode Mania K Sima,b, C Kuswantob, PS Woonb, GL Yangc, YY Sitohd, WL Nowinskic a General Psychiatry, Institute of Mental Health, Singapore, bResearch Department, Institute of Mental Health, Singapore, cSingapore Bioimaging Consortium, ASTAR, Singapore, dNeuroradiology, National Neuroscience Institute, Singapore Pattern Classification of gray Matter Density in Unipolar, Bipolar I, and Bipolar II Patients using Voxel-based Morphometry and Bayesian Classifier TP Sua,b,c, LF Chenc,d, YS Chene, CY Chanc, PS Leef, PC Tua, JC Hsiehc,d a Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan, bDivision of Psychiatry, School of Medicine, National Yang-Ming University, Taipei, Taiwan, c Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan, dDepartment of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, e Department of Computer Science, National Chiao Tung University, Hsinchu, Taiwan, f Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan DNA hypomethylation of MB-COMT promoter and the first exon of HTR2A in DNA derived from saliva in schizophrenia and bipolar disorder HM Abdolmalekya S Nohesaraa, M Ghadirivasfia, S Mostafavib, H Ahmadkhanihaa, M Eskandaric, S Thiagalingamd, aMental Health Research Center, Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran, bDepartment of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA, cLaboratory of Nutrition and Metabolism at BIDMC, Harvard Medical School, Boston, MA, USA, dDepartment of Medicine, Biomedical Genetics, Boston University School of Medicine, Boston, MA, US. QUESTION & ANSWERS

Biomarkers in Mood Disorders: Integrative Analysis Across Molecular, Imaging and Clinical Domains Chair: Sidney H. Kennedy, University of Toronto, Canada Biomarkers in Mood Disorders: What role might genes play? Alan Young Imperial College London, UK Biomarkers in Mood Disorders: Integrating neuroimaging and clinical markers Sidney H. Kennedy, University of Toronto, Canada Plasma proteomics and High Dimensional Bioinformatics: New tools for understanding the mechanisms of depressive illness. Kenneth R. Evans, Ontario Cancer Biomarker Network Imaging central gABA and glutamate abnormalities in MDD gregor Hasler, Psychiatric University Hospital Bern, Switzerland QUESTION & ANSWERS 16:00 17: 30 BREAKINg NEWS 3 Oral presentations Chairs: Tung Ping Su, Taipei Veteran General Hospital,Taiwan Ricardo Moreno, Brazil Early identification of affective disorder, first results from a 5 to 7 years followup high-risk study M Vinberg, LV Kessing Psychiatric Center Copenhagen, University Hospital of Copenhagen. Denmark Association between Premenstrual Mood Exacerbation in Bipolar Disorder with Reproductive Hormone-Related Mood Disturbances: Findings from STEP-BD RS Diasa,b, B Lafera, AA Nierenbergb, GS Sachsb, H Joffec a Bipolar Disorder Research Program, Department and Institute of Psychiatry, University of So Paulo Medical School, bBipolar Clinic and Research Program - Massachusetts General Hospital, cCenter for Womens Mental Health, Massachusetts General Hospital. DOLMABAHCE C

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Day 3: Friday, March 16, 2012


16:00 17: 30 PARALLEL 4 ENBREC Chair: Lars Vedel Kessing, University of Copenhagen, Denmark Research networks for bipolar disorder: Why and What For? Eduard Vieta, University of Barcelona, Spain Factors associated with age at onset of bipolar disorders Michael Bauer, Technische Universitat Dresden, Germany ENBREC, State of the art and recent development Chantal Henry, INSERM, France QUESTION & ANSWERS 17:30 19:00 POSTER SESSION II FOYER - 1 ST FLOOR TOPKAPI B HALL 08:00 09:00 KEYNOTE 4

Day 4: Saturday, March 17, 2012


ANADOLU AUDITORIUM

WPA Address Chair: Levent Kuey, World Psychiatric Association Secretary General, Turkey Depression among Womens Adolescents: A WPA Concern Pedro Ruiz, University of Miami Miller School of Medicine, USA QUESTION & ANSWERS 09:00 10:30 CORE SYMPOSIUM 5 Neuroimaging and Neurocognition Chairs: Sophia Frangou, Kings College London, UK Caleb Adler, University of Cincinnati, USA Examination of the predictive value of structural MR scans in bipolar disorder: a pattern classification approach Sophia Frangou, Kings College London, UK ISBD Neuroimaging Task Force Report Caleb Adler, University of Cincinnati, USA Imaging genetic risk in bipolar disorder Andrew McIntosh, Edinburgh University, UK Imaging Oxidative Stress Cascade in Bipolar Disorder Lakshmi Yatham, The University of British Columbia, Canada QUESTION & ANSWERS 10:30 10:45 Coffee Break ANADOLU AUDITORIUM

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

Day 4: Saturday, March 17, 2012


10:45 12:15 CORE SYMPOSIUM 6 ANADOLU AUDITORIUM

Meeting the Needs of Our Patients through Advocacy: Cross-cultural Similarities and Differences Chairs: Kyooseob Ha, Seoul National University, South Korea Lars Haggstrom, Central Hospital, Halmstad, Sweden Challenging the Stigma of Bipolar Disorders Manuel Sanchez de Carmona, ISBD Mexican Chapter, Mexico Where do Bipolar Support groups fail? Lessons from Turkey Tezer Orhan, Lithium Association, Turkey International issues in patient advocacy Allen Doederlein, Depression and Bipolar Support Alliance (DBSA), USA QUESTION & ANSWERS

POSTER SESSIONS

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

POSTER SESSION I
Thursday, 15 March 2012 17.30 -19.00
*by surname alphabetic order

P01 Inhibitory controls in bipolar and major depressive disorder: a NIRS study H Akashi, N Tsujii, S Sakai, W Mikawa, E Kirime, O Shirakawa Department of Neuropsychiatry, Kinki University Faculty of Medicine, Osaka-sayama, Osaka, Japan P02 Attention deficit/hyperactivity disorder comorbid with bipolar disorder does not enhance cognitive impairment C Akkayaa, C gunduza, S Cangurb, SS Ekera a Uludag University Medical Faculty, Psychiatry and b Biostatistics Departments, Gorukle, Bursa, Turkey P03 The relationship between residual symptoms and sociodemographic features, characteristics of the disorder and the treatment and functionality of the remitted bipolar disorder patients C Akkayaa, M Canbazoglua, S Cangurb, S Kirlia a Uludag University Medical Faculty, Psychiatry and b Biostatistics Departments, Gorukle, Bursa, Turkey P08 Comparison of coping strategies and personality traits between bipolar patients and control group T ksza, K Altnbaa, E Kurta, ET Oralb a Rait Tahsin Mood Clinic, Bakrky Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Istanbul,Turkey, bDepartment of Psychology, TC Istanbul Commerce University, Istanbul, Turkey P12 Comparison of comorbidity pattern of Obsessive Compulsive disorder in children and adults with Bipolar I disorder F Assariana , R Davarib, F Arab golc, Z ghoreishid a Assistant professor, Akhavan Psychiatric Hospital, Kashan University of Medical Sciences, Kashan/ Iran, bAssistant professor, Imam Hossein Hospital , Shahid Beheshti University of Medical Sciences,Tehran , Iran, cPsychiatrist, Imam Hossein Hospital , Shahid Beheshti University of Medical Sciences,Tehran , Iran, dAssistant professor, Akhavan Psychiatric Hospital , Kashan University of Medical Sciences, Kashan, Iran

P13 Psychomotor speed and coordination in bipolar disorder I Atagna, Balabanb, D Yeilbaa, S Yeilyurta, C Keskinklc, C Evrend a Bakrky Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Istanbul,Turkey 5th Psychiatry Department, b12th Psychiatry Department, c3rd Neurology Clinic, dAMATEM Alcohol and Substance Use Disorders Unit P15 To compare bipolar disorder and attention deficit hyperactivity disorder with regard to neurological soft signs N Leventa, S Tmkayab, F Ateib, NK Ouzhanolub a Kumluca Goverment Hospital Psychiatry Department, Antalya, Turkey, bPamukkale University Psychiatry Department, Denizli, Turkey P16 Reliability and Validity of Turkish Version of Biological Rhythms Interview of Assessment in Neuropsychiatry O Aydemira, C Akkayab, K Altinbasc, K Korad, D Suculluoglu Dikicia, F Akdeniza, F Kalaycia, ET Orale, S Vahipf a Celal Bayar University School of Medicine Department of Psychiatry, Manisa 45010, Turkiye, b Uludag University School of Medicine Department of Psychiatry, Bursa, Turkiye, cBakirkoy State Hospital for Mental Health and Neurological Disorders, Rasit Tahsin Center for Mood Disorder, Istanbul, Turkiye, dMarmara University School of Medicine Department of Psychiatry, Istanbul, Turkiye, eIstanbul Trade University, Department of Psychology, Istanbul, Turkiye, fEge University School of Medicine Department of Psychiatry, Izmir, Turkiye P17 Reliability and Validity Study of the Turkish Version of Functioning Assessment Short Test in Bipolar Disorder O Aydemir, B Uykur Celal Bayar University School of Medicine Department of Psychiatry, Manisa, Turkiye P22 A Comparative Study of Heart Rate Variability among Adolescent Siblings of Patients with Bipolar Disorder Type I and Matched Controls YPS Balhara and KES Unni Department of Psychiatry, Lady Hardinge Medical College and SSK Hospital, New Delhi, India-110001

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P23 Differences in psychophysiological parameters in patients with bipolar disorder, depression remitted and healthy controls submitted to a cognitive paradigm. AT Ballesterosa, H Ortegaa, C Becerraa, MI Barrerab, F Romoc a Affective disorders department, National Institute of Psychiatry Ramn de la Fuente Muiz, Mxico, bBiofeedback department, National Institute of Psychiatry Dr. Ramn de la Fuente Muiz, Mxico, cPsychiatry and Mental Health department, National Autonomous University of Mexico, Mxico P24 Imipramine reverses depressive-like parameters in pneumococcal meningitis survivor rats T Barichelloa, g Miliolia, JS generosoa, A Collodela, C Silvestrea, AP Moreiraa, MC Vilelab, CM Comimc, AL Teixeirab, J Quevedoc a Laboratrio de Microbiologia Experimental, PPGCS, Universidade do Extremo Sul Catarinense, Cricima, SC, Brazil, bLaboratrio de Imunofarmacologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil, cLaboratrio de Neurocincias, PPGCS, Universidade do Extremo Sul Catarinense, Cricima, SC, Brazil P25 Dysphoric State in Mood Disorders: a clinical marker of Bipolar Disorder? S Barroilheta,b, P Vohringerb,c, M Correaa, L Riscoc, N ghaemib a Escuela de Psicologa, Universidad de los Andes, Santiago, Chile, bMood Disorder Program, Tufts Medical Center, Boston, MA, USA, cClnica Psiquitrica Universitaria, Facultad de Medicina, Universidad de Chile, Santiago, Chile P29 Burden in care givers of patients with schizophrenia and mood disorders: a cross sectional comparative study from central India. MC Bhisea, AV Rathodb, PB Beherec a Assistant Professor of psychiatry M.G.M. Medical College & Research Centre Aurangabad Maharashra state, India, bConsultant Psychiatrist Manasamruddhi clinic Amarawati Maharashtra state, India, cDirector Professor & Head department of psychiatry M.G.I.M.S. Sevagram Wardha Maharashtra state, India P33 An Adolescent with Aspergers Disorder and Comorbid Bipolar Disorder: A Case Report T Bildik, B Ozbaran, S Gokcen, S Korkmaz-Cetin, S Erermis, C Aydn Ege University Medical School, Department of Child Psychiatry, Izmir, Turkey P34 The Turkish Version of the Mixed State Scale in Bipolar Disorder S. guneya, S. Unalb, E.A. Mutluc, R.Bilicid a Psychology, Ankara University, Ankara-Turkiye, bPsychiatry, Inonu University, Malatya-Turkiye, c Psychiatry, Governmental Hospital, Van-Turkiye, d Psychiatrist, Elazig Governmental Hospital, Ministry of Health, Elazig-Turkey

P35 Antidepressant-induced hypomanic switch predictors in social anxiety disorder patients A Koyuncua, Z Binbayb, I Ozyildirimc, E Ertekind a Department of Psychiatry, Bahat Group Hospitals, Istanbul,Turkey, bDepartment of Psychiatry, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey,cDepartment of Psychiatry, Medicana International Hospital, Istanbul,Turkey, dDepartment of Psychiatry, Istanbul University Istanbul Medical Faculty, Istanbul,Turkey P36 The clinical impact of mood disorder comorbidity on social anxiety disorder A Koyuncua, I Ozyildirimb, Z Binbay c, I Ozyildirimc, E Ertekind a Department of Psychiatry, Bahat Group Hospitals, Istanbul,Turkey, bDepartment of Psychiatry, Medicana International Hospital, Istanbul,Turkey, cDepartment of Psychiatry, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey, dDepartment of Psychiatry, Istanbul University Istanbul Medical Faculty,Istanbul,Turkey P37 COMT allele (Met158) modulates facial emotion recognition in bipolar disorder I mood episodes and in healthy controls Bio DS, Soeiro-de-Souza Mg, Moreno DH, Moreno RA Mood Disorders Unit (GRUDA), Department and Institute of Psychiatry, School of Medicine, University of So Paulo (IPq HC-FMUSP), Brazil P38 Is there a functional brain imaging biomarker of bipolar disorder? A systematic review and meta-analysis E Bora, Christos Pantelis Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne, Melbourne, VIC, Australia P39 Improving Criteria for Differentiating Bipolar Disorder and Major Depressive Disorder in Patients Experiencing a Major Depressive Episode CL Bowdena, J Angstb, JM Azorinc, E Vietad, A gammab, A Younge a University of Texas Health Science Center, San Antonio, Texas, USA, bZurich University, Zurich, Switzerland, cSt Marguerite Hospital, Marseilles, France, dUniversity of Barcelona, Barcelona, Spain, eImperial College, London, United Kingdom

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P40 Altered levels of neuron specific enolase (NSE) in patients with bipolar disorder and schizophrenia SP Brunaa,b,e, Mg Carolinaa,b,e, S Lauraa,b,e,f, MC Keilab,e, PK Flvioa,b,c,e, Sg Clarissaa,b,d,e a Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil, bLaboratory of Molecular Psychiatry, Hospital de Clnicas de Porto Alegre, Porto Alegre, Brazil, cBipolar Disorder Program, Hospital de Clnicas de Porto Alegre (PROTHAB - HCPA) Hospital de Clinicas de Porto Alegre, Porto Alegre ,Brazil, dSchizophrenia Program, Hospital de Clnicas de Porto Alegre (PRODESC - HCPA), HospitalClnicas de Porto Alegre, Porto Alegre , Brazil, eNational Institute of Science and Technology in Translational Medicine (INCT-TM), Brazil, fGraduate Program in Biological Sciences: Biochemistry (PPGBioq UFRGS), Porto Alegre, Brazil P43 Anxiety disorders in Rapid-Cycling Bipolar Youths: A Cohort Study of a National Managed Care Database R Castillaa,b, A Camachoc a Department of Psychiatry, Epidemiology and Pharmacoepidemiology, University of South Carolina, Columbia, South Carolina, USA, bSchool of Pharmacy, Temple University, Philadelphia, PA, USA, cDepartment of Family, Preventive Medicine and Psychiatry, University of California, San Diego, USA P44 Can serum bdnf levels be identified as a candidate endophenotype in bipolar disorder? D Ceylana, A zerdemab, N Grz Yalnc, C Hdrolub, Y Aslana, B Baca, M Baynd, Aydemire, C Cengisize, H Resmif, Z Tuncaa a Department of Psychiatry, Dokuz Eylul University Medical School, Izmir, Turkey, bDepartment of Neuroscience, Dokuz Eylul University Health Sciences Institute, Izmir, Turkey, cDepartment of Psychiatry, Etlik Zubeyde Hanim Womens Health Teaching and Research Hospital, Ankara, Turkey, d Department of Psychiatry, Nevsehir Dr Sevki Atasagun Public Hospital, Nevsehir, Turkey, e Department of Psychiatry, Celal Bayar University Medical School, Manisa, Turkey, fDepartment of Biochemistry, Dokuz Eylul University Medical School, Izmir, Turkey P45 DNA damage in Bipolar Disorder: A quantitative assessment by using gas ChromatographyIsotope Dilution Mass Spectrometry (gC-MS) D Ceylana, g Tunab, G Krkalb, M Dizdaroluc, Z Tuncaa, S Yeilyurta, A zerdema a Department of Psychiatry, Dokuz Eylul University Medical School, Izmir, Turkey, b Department of Biochemistry, Dokuz Eylul University, Izmir, Turkey, c Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA

P55 Associations of selective attention with trait features in remitted bipolar patients T Novaka, L praha, MZ Dernovekb, R Tavarb a Sociomedical Institute, Scientific Research Centre at the Slovenian Academy of Sciences and Arts, Ljubljana, Slovenia, bUniversity Psychiatric Hospital, Department of Psychiatry, Ljubljana, Slovenia P56 How to facilitate the diagnosis of bipolar disorder: The use of long and short version of the TEMPS-A Scale (Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire) B Dolenca, L praha, MZ Dernovekb, R Tavarb a Sociomedical Institute, Scientific Research Centre of the Slovenian Academy of Sciences and Arts, Ljubljana, Slovenia, bUniversity Psychiatric Hospital, Department of Psychiatry, Ljubljana, Slovenia P57 Association of homocysteine and methionine levels with cognition and functioning in bipolar disorder gO Doganavsargil-Baysal, Z gokmenb, H Akbas, B Cinemre, O Metin, T Karaman a Akdeniz University Medical Faculty Antalya, Turkey, bKackar State Hospital, Rize, Turkey P58 Levels of TNF-, soluble TNF receptors (sTNFR1, sTNFR2) and cognitive impairment in bipolar disorder gO Doganavsargil-Baysal, H Akbasb, B Cinemre, O Metin, Z gokmenc, F Davranb Akdeniz University, Department of Psychiatry, Antalya, Turkey, bAkdeniz University, Department of Biochemistry, Antalya, Turkey, cKackar State Hospital, Rize, Turkey P63 Factors related to misdiagnosis in bipolar disorder with psychotic symptoms M Fernandezc, I Ortegab,c, S Barbeitoa,b,c, B garcac, O Napalc, A gonlez-Pintoa,b,c a CIBER Center of Mental Health, Santiago Apstol Hospital, Osakidetza, Vitoria, Spain, bStanley Institute International Mood Disorders Research Center (03-RC-003), Vitoria, Spain, cSantiago Apstol Hospital, Vitoria, Spain P66 Is cognitive impairment a core element in the affective psychosis? N Freund, P garca, C Harkous, C Bonilla, M Blanco Department of Psychiatry, Hospital Universitario Prncipe de Asturias, Alcal de Henares, Espaa P67 Mixed episodes of bipolar disorder vs personality disorder N Freund, C Harkous, C Bonilla, M Blanco, P garca Department of Psychiatry, Hospital Universitario Prncipe de Asturias, Alcal de Henares, Espaa

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P68 Pathophysiology of bipolar disorder and inflammatory mediators N Freund, C Bonilla, M Blanco, P garca, C Harkous Department of Psychiatry, Hospital Universitario Prncipe de Asturias, Alcal de Henares, Espaa P70 Assessment of Mood Disorders Prevalence in Brazilian Military Population AL gadelha, LM Sarin, S Leite, N Ruy, LP grinberg, JA Del Porto Programa de Disturbios Afetivos (PRODAF) Universidade Federal de So Paulo, So Paulo, Brazil P72 The staging model of bipolar disorder and cognitive functioning: a comparison with patients with schizophrenia R Massudaa, M Sulzbacha, P goia, J Bckera, J Narvaeza, L Czepielewskia Lg Costaa, L Silveiraa, M Constanzia, R Reckziegela, M Vasconcelosa, NS Kapczinskia, M Kauer-SantAnnab, F Kapczinskib, CS gamab a Molecular Psychiatry Laboratory, Hospital de Clnicas de Porto Alegre, Porto Alegre, Brazil, bINCT Translational Medicine, Hospital de Clnicas de Porto Alegre, Porto Alegre, Brazil P73 Misdiagnosis of bipolar disorder P garca, N Freund, B De Diego, C Harkous, JA Surez Department of Psychiatry, Hospital Universitario Prncipe de Asturias, Alcal de Henares, Spain P74 Bipolar disorder in youth people P garca, N Freund, B De Diego, C Harkous, P Hernndez Department of Psychiatry, Hospital Universitario Prncipe de Asturias, Alcal de Henares, Spain P78 1H MRS of hippocampus in bipolar disorder after recovery from the first episode of mania AD gigantea, B Lafera, AL MacKayb, LN Yathamc a Bipolar Research Program, Department and Institute of Psychiatry, University of So Paulo Medical School, So Paulo, Brazil, bDepartment of Physics and Astronomy, University of British Columbia, Vancouver, Canada, cDepartment of Psychiatry, University of British Columbia, Vancouver, Canada. P79 Brain glutamate levels measured by MRS in patients with bipolar disorder: a meta-analysis AD gigantea,b, DJ Bonda, B Lafera,b, RW Lama, LT Youngc, LN Yathama a Department of Psychiatry, University of British Columbia, Vancouver, Canada, bBipolar Research Program, Department and Institute of Psychiatry, University of So Paulo Medical School, So Paulo, Brazil, cCentre for Addiction & Mental Health, University of Toronto, Toronto, Canada

P80 Twenty-year multi-follow-up of hallucinations in psychotic and mood disorders VM gogharia, M Harrowb, LS grossmanb, C Rosenb a Departments of Psychology and Psychiatry and Hotchkiss Brain Institute, University of Calgary, Calgary, Canada, bDepartment of Psychiatry, University of Illinois-Chicago, Chicago, Illinois, USA P81 A Magnetic Resonance Spectroscopy study of the Anterior Cingulate Cortex in Youth with Emotional Dysregulation A gonenc, J Wozniak, J Biederman, g Joshi, A Henin Harvard Medical School, Department of Psychiatry, Boston, MA, USA P83 Psychosocial functioning in first-versus multiple episode bipolar patients I gonzlez-Ortegaa, M Fernndeza, S Ruiz de Azaa, AR Rosab, E Vietab, A gonzlez-Pintoa a Department of Psychiatry, Santiago Apstol Hospital, CIBERSAM, Vitoria, Spain, bBipolar Disorders Program, Institute of Neurosciences, Hospital Clinic, IDIBAPS, CIBERSAM, Barcelona, Spain P86 Role of biomarkers in the staging of bipolar disorder: inflammatory factors and oxidative stress I grandea,b, PV Magalhaesb, I Chendoa,c, L Stertza, gR Friesa, CS gamaa, E Vietab, F Kapczinskia a Bipolar Disorder Program and Laboratory of Molecular Psychiatry, National Institute for Translational Medicine, INCT-TM Hospital de Clnicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil, bBipolar Disorders Program, Clinical Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain, c Hospital de Santa Maria, Lisboa, Portugal P87 Social cognition in young people at-risk for bipolar disorder: Associations with neurocognition and emotion regulation MJ greena, g Robertsa, b, C McCormacka,b, A Franklanda,b, A Wrighta,b, Jesseca Rowlanda,b, Dusan Hadzi-Pavlovicb, F Levya, R Lenroota,c, and PB Mitchella,b a School of Psychiatry, University of New South Wales; bBlack Dog Institute, Prince of Wales Hospital, Hospital Rd, Randwick NSW, Australia, cNeuroscience Research Australia, Randwick, NSW, Australia

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P89 Analysis of mitochondrial complexes activity in peripheral blood mononuclear cells of bipolar disorder, schizophrenic and healthy subjects CM guberta,d, BS Panizzuttia,d, B Pfaffensellera,d,e, gT Rezind,f, M Kunza,b,d, R Massudaa,c,d, L Stertza,d,e, C gamaa,c,d, F Kapczinskia,b,d a Laboratory of Molecular Psychiatry, Hospital de Clnicas de Porto Alegre, Porto Alegre (RS), Brazil, bBipolar Disorder program, Hospital de Clnicas de Porto Alegre, Porto Alegre, Brazil, c Schizophrenia Program , Hospital de Clnicas de Porto Alegre, Porto Alegre, Brazil, dINCT National Institute for Translational Medicine, Brazil, ePostgraduate Program in in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, f Postgraduate Program in Health Sciences, Universidade do Extremo Sul Catarinense, Cricima, SC, Brazil P90 Health Help-Seeking Behavior in Patients with Bipolar Disorder: The effect of sex on use of medicine and health help-seeking behavior in patients with bipolar disorder M Gndoan, Yenilmez, A Musmul, A zkr University of Eskisehir Osmangazi School of Medicine, Psychiatric Clinic, Eskisehir, Turkey P91 Brain Oscillations in Bipolar Disorder as Emerging Biomakers B Gntekina, A zerdema,b,c, Erol Baara a Brain Dynamics, Cognition, and Complex Systems Research Center, Istanbul Kltr University, Istanbul, Turkey, bDepartment of Psychiatry, Faculty of Medicine Dokuz Eylul University, Izmir, Turkey, cDepartment of Neuroscience, Health Sciences Institute, Dokuz Eylul University, Izmir, Turkey P93 Variations in CYP2D6 metabolism in bipolar disorder: a study on patients hospitalized in emergency psychiatric ward C Gzeyab, AE Vaalerab, UF Maltcd, OA. Andreassence, g Morkenab a St. Olavs University Hospital, stmarka Psychiatric Department, Trondheim, Norway, b Department of Neuroscience, Faculty of Medicine, NTNU, Trondheim, Norway, cInstitute of Clinical Medicine, University of Oslo, Oslo, Norway, dDepartment of Neuropsychiatry and Psychosomatic Medicine, Oslo University Hospital, Oslo, Norway, eDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway P94 Moral judgments in euthymic patients with bipolar disorder* RY Haa,b, TY Kima, S Leeb, V Ryuc, HS Choa,b a Department of Psychiatry, Collge of Medicine, Yonsei University, Seoul, South Korea, bInstitute of Behavioral Science in Medicine, College of Medicine, Yonsei University, Seoul, South Korea, c Department of Psychiatry, College of Medicine, Konyang University, Daejeon, South Korea, * This study was supported by a grant (A101915) from the Korea Healthcare Technology R&D Project of the Ministry of Health & Welfare of the Republic of Korea

P95 Neuropsychological correlates of autobiographical memory in bipolar disorder: a preliminary study* RY Haa,b, J Suna, S Leeb, V Ryuc, HS Choa,b a Department of Psychiatry, Collge of Medicine, Yonsei University, Seoul, South Korea, bInstitute of Behavioral Science in Medicine, College of Medicine, Yonsei University, Seoul, South Korea, c Department of Psychiatry, College of Medicine, Konyang University, Daejeon, South Korea,* This study was supported by a grant (A101915) from the Korea Healthcare Technology R&D Project of the Ministry of Health & Welfare of the Republic of Korea P96 Regional gray matter abnormalities in first-episode bipolar disorder TH Haa,b, DJ Bonda, K Hab, LN Yathama a Department of Psychiatry, University of British Columbia, Vancouver, Canada, bDepartment of Psychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea P97 Creatine alterations in the hippocampus in bipolar I disorder - a 3T 1H-MRS study BCM Haarmana, RF Riemersma-Van der Leka, H.Burgerb, Horkova, RJ Renkenc, AJ SibeijnKuiperc, WA Nolena a Department of Psychiatry, bDepartment of Epidemiology, cDepartment of Neuroimaging Center University Medical Center Groningen, Groningen, The Netherlands P99 Default mode network in children at risk for bipolar disorder: Preliminary resting-state fMRI findings L Hanforda, gB Hallb, BN Freyc,d, RB Sassic a MiNDS Program, McMaster University, Hamilton, Canada, bPsychology Department, McMaster University, Hamilton, Canada, cMood Disorders Program and d Womens Health Concerns Clinic, St. Josephs Healthcare, Hamilton, Canada P102 Affective prosody in remitted patients with bipolar I disorder CM Hoertnagla, M Mhlbacherc, F Biedermannb, N Yalcinb, S Baumgartnerb, AS Rauchb, g Kemmlera, C Benecked, A Hoferb a Medical University Innsbruck, General and Social Psychiatry Division, Innsbruck, Austria, b Medical University Innsbruck, Biological Psychiatry Division, Innsbruck, Austria, c Private Medical University Salzburg, Department of Psychiatry and Psychotherapy, Salzburg, Austria, d Leopold Franzens University Innsbruck, Department of Psychology, Innsbruck, Austria P103 Characteristics of late onset bipolar disorder: Evaluation using the Bipolarity Index N Horikawa, T Nakamura, M Tomita, N Uchimura Department of Neuropsychiatry Kurume University School of Medicine, Fukuoka, Japan

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P105 Cognitive functioning during depressive and manic episodes in bipolar disorder N Ioannidia, g Konstantakopoulosa,b, D Ploumpidisa, D Sakkasc, gN Papadimitrioua, P Oulisa a First Department of Psychiatry, Eginition Hospital, Athens University Medical School, Greece, b Section of Cognitive Neuropsychiatry, Department of Psychiatry, Institute of Psychiatry, Kings College London, United Kingdom, cDepartment of Psychiatry, General Hospital G. Gennimatas, Greece P109 More eveningness in the patients with BP type II than BP type I disorder JK Chunga, KY Leea, SH Jeongb, EJ Kima, YM Ahnc, EJ Jooa a Department of Neuropsychiatry, Eulji University School of Medicine, Eulji Generall Hospital, Seoul, Korea, bDepartment of Neuropsychiatry, Eulji University School of Medicine, Eulji University Hospital, Daegeon, Korea, cDepartment of Psychiatry, Seoul National University College of Medicine, Seoul, Korea P112 Effect of valproic acid through regulation of NMDA receptor-ERK signaling in sleep deprivation rats, the manic-like animal model WS Kanga, HJ Parkb, JW Paika, EJ Kimc, JW Kima a Department of Neuropsychiatry, School of Medicine, Kyung Hee University, Seoul, Republic of Korea, bKohwang Medical Research Institute, School of Medicine, Kyung Hee University, Seoul, Republic of Korea, c Department of Neuropsychiatry, Eulji University School of Medicine, Seoul, Republic of Korea P114 Possible preattentive auditory dysfunction in bipolar disorder: a magnetoencephalography study S Katsuki, T Onitsuka, N Oribe, R Tsuchimito, S Hirano, T Ueno, Y Hirano, I Nakamura, Y Oda, S Kanba Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan P117 Are Depressive Episodes of Bipolar Disorder I and II different? S Kesebira, A Bayraka, B nbola, Turana, A nala, S akrb a Erenky Psychiatric Training and Research Hospital, Istanbul, Turkey bIstanbul University, Istanbul Medical School, Psychiatry Department, Istanbul, Turkey

P123 The Neurocognitive profile in depressed therapy resistant bipolar disorder inpatients U Kesslera, H Schoeyenb, OA Andreassenc,d, P Bergsholme, gE Eidef,g, A Hammarh,i, U Maltj,k, K Oedegaarda, g Morkenl,m, K Sundetc,n, AE Vaalerl,m a Moodnet Research Group, Psychiatric Division, Haukeland University Hospital, Bergen, Norway b Moodnet Research Group, Psychiatric Division, Stavanger University Hospital, Stavanger, Norway, cDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway, d Institute of Clinical Medicine, University of Oslo, Oslo, Norway, e Moodnet Research Group, Frde Hospital, Norway, fCentre for Clinical Research, Haukeland University Hospital, Bergen, Norway, g Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway, h Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway, i Division of Psychiatry, Haukeland University Hospital, Bergen, Norway, jInstitute of Psychiatry, University of Oslo, Oslo, Norway, kDepartment of Neuropsychiatry and Psychosomatic Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway, lDepartment of Neuroscience, Faculty of Medicine, NTNU, Trondheim, Norway, mSt. Olavs University Hospital, Division of Psychiatry, Trondheim, Norway, nDepartment of Psychology, University of Oslo, Oslo, Norway P124 Is CHRNA7 associated with childhood inattention of bipolar disorder? EJ Jooa, EJ Kima, KY Leea, YM Ahnb, YS Kimb a Department of Neuropsychiatry, Eulji University School of Medicine, Eulji General Hospital, Seoul, Korea b Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Seoul, Korea P125 The association between serum leptin, active ghrelin, adiponectin and metabolic syndrome in patients with bipolar disorder EY Kima, HJ Leea, NY Leea, HY Yub, YS Kima,b, YM Ahna,b a Department of Psychiatry, Seoul National University Hospital, Seoul, Korea, bDepartment of Psychiatry and Institute of Human Behavioral Medicine, Seoul National University College of Medicine, Seoul, Korea P126 Concurrent validity of the Korean version of the Parent and Adolescent general Behavioral Inventories HW Kima, YH Jooa, J Parka, EA Youngstromb a Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea b Department of Psychology, University of North Carolina, Chapel Hill, NC, USA

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P127 Seasonality and circadian preference in patients with bipolar disorder and their unaffected siblings JS Kima, J Choia, JH Baeka, JS Choia, JS Kwonb, KS Honga a Department of Psychiatry, Sungkyunkwan University School of Medicine,Samsung Medical Center, Seoul, Korea, bDepartment of Neuropsychiatry, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea P128 Intracerebroventricular administration of ouabain, a Na/K-ATPase inhibitor, activates tyrosine hydroxylase through extracellular signal-regulated kinase in rat striatum SH Kima, HS Yub, YS Kima,b, YM Ahna a Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Republic of Korea, b Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea P129 Reward Learning in Patients with Bipolar Disorder: Findings from a Probabilistic Reward Task TY Kima, V Ryuc, RY Haa, SJ Leeb, HS Choa,b a Department of Psychiatry, Yonsei University College of Medicine, Seoul, Korea b Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea c Department of Psychiatry, KonYang University College of Medicine, Nonsan, Korea P131 Increased whole blood brain-derived neurotrophic factor in healthy individuals with a family history of affective disorder: a case-control study U Knorra,c, MHg Sndergaardb, P Koefoedc, A Jrgensena,b, M Faurholt-Jepsena, M Vinberga, U getherc, LV Kessinga a Psychiatric Centre Copenhagen, Rigshospitalet, University Hospital of Copenhagen, Denmark, b Laboratory of Neuropsychiatry, University Hospital of Copenhagen, Rigshospitalet and University of Copenhagen, Denmark, cCentre for Pharmacogenomics, Department of Neuroscience and Pharmacology, University of Copenhagen, Denmark P137 Serum level of leptin, ghrelin, adiponectin according to mood status in patients with bipolar disorder HJ Leea, NY Leea, EY Kima, HY Yub, YM Ahna, b, YS Kima, b a Department of Psychiatry, Seoul National University Hospital, Seoul, Korea, bDepartment of Psychiatry and Institute of Human Behavioral Medicine, Seoul National University College of Medicine, Seoul, Korea

P138 nF1A gene can be a susceptibility gene for seasonal pattern mania: a gWAS of bipolar disorder HJ Leea, Hg Woob, TA greenwoodc, DF Kripkec, JR Kelsoec,d the Bipolar genome Study (BigS) Consortium a Department of Psychiatry, Korea University College of Medicine, Seoul, South Korea, b Department of Physiology, Ajou University College of Medicine, Suwon, South Korea, c Department of Psychiatry, University of San Diego, La Jolla, CA, USA, dSan Diego VA Healthcare System, San Diego, CA, USA P139 Interaction of the DrD3 and BDnF gene variants in Subtyped Bipolar Disorder SY Leea,b, RB Lua,b,c,d a Department of Psychiatry, cInstitute of Behavioral Medicine, and dInstitute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan; bDepartment of Psychiatry, National Cheng Kung University Hospital, Tainan, Taiwan P140 Subjective and physiological emotional reactivity in normothymic bipolar patients M Lemaire, N Hernandez, J Martineau, W El-Hage Inserm UMR-S930 CNRS ERL 3106, Universit Franois Rabelais & CHRU, Tours, France P143 What is the contribution of executive dysfunction to the cognitive profile of bipolar disorder? A well controlled direct comparison study. JP LOPERA-VSQUEZ a, V BELLa, CA LPEZb, a Neuropscychology, Universidad de Antioquia,Colombia, bPsychiatry, Universidad de Antioquia, Colombia P144 Descriptive features of mixed bipolar outpatients JM Lpez-Santin , M Ibarra Jato, R Bordas Reig, N Moll Jurado, MA Lpez-Bertran, B garca Balado, J guinart Prados, N Ribas Fit N Mental Health Center Mart i Juli, Consorci Parc de Salut Mar de Barcelona, Santa Coloma de Gramanet, Spain P148 Risk scale bipolar disorders - Usefulness in primary care AJ Madueo, M Ruiz, MA Luque, N Dominguez, F Rodriguez, L De Lara La Laguna Primary Care Health Center, Andalusian Health Service, Cdiz, Spain P151 Bipolar Affective Disorder and Substance Use: The Dual Diagnosis in Treatment Seeking Patients Experience from Chronic Conflict Zone, Kashmir, India A Majida, MA Margoobb, AW Khana a Department of psychiatry, SKIMS MCH, bGovt Medical College, Srinagar, INDIA

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

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P152 Pregnancy planning and reproductive health care in women with bipolar disorder. E Marengo, DJ Martino, A Igoa, g Fassi, J Teitelbaum, M Scpola, SA Strejilevich a Bipolar Disorders Program, Neuroscience Institute, Favaloro University, Buenos Aires, Argentina. P155 gROUP-based trajectory modeling (gBTM): a good model for understanding patterns of symptom change in acute bipolar mood episodes K MBailaraa,b,i, O Cosnefroyc, E Vietad, J Scotte, S gardb, A Desageb, C Henry f,g,h,i a Laboratory of Psychology, University Bordeaux, Bordeaux, France, bDepartment of Adult Psychiatry, Hospital Charles Perrens, Bordeaux, France, cUniversity Pierre-Mends-France, Laboratory of Science Education, Grenoble 2, France, dBipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain, eAcademic Psychiatry, Institute of Neuroscience, Newcastle University, United Kingdom, fINSERM, Unit U955, Crteil,France, g University Paris-Est, Faculty of Medecine, UMR-S 955, Crteil, France, hAP-HP, Group HenriMondor Albert-Chenevier, Psychiatry, Crteil, France, iFondation Fondamental, Crteil, France P158 genetic contribution to individual variation in binocular rivalry, an endophenotype for bipolar disorder SM Millera, NK Hansellb, TT Ngoa, gB Liuc, JD Pettigrewd, MJ Wrightb, Ng Martinb a School of Psychiatry, Monash University, Melbourne, VIC, Australia bGenetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, QLD, Australia cCentre for Systems Biology, University of Southern Queensland, Toowoomba, QLD, Australia, dQueensland Brain Institute, University of Queensland, Brisbane, QLD, Australia P159 First manic episode patients - Drug consumption, cognitive and general functioning: 1 year follow-up M Martnez-Cengotitabengoaa,b, A Ugartea,b, P Vegaa,b, P Lpeza,b, M gutirreza,b,c, A gonzlezPinto a,b,c a CIBERSAM, Centro de Investigacin Biomdica en Red de Salud Mental, Barcelona, Spain, b Santiago Hospital, Vitoria, Spain, cUniversity of the Basque Country, Basque Country, Spain P161 The difference of morphometric abnormalities in unaffected first-degree relatives of bipolar and major depressive disorder T Matsubaraa, K Matsuoa, M Nakanoa, M Nakashimaa, K Egashirab, M Suetsugia, N Matsunagac, Y Watanabea a Neuropsychiatry, Department of Neuroscience, Yamaguchi Univ, Ube,Yamaguchi, Japan, b Neuropsychiatry, Yamaguchi Grand Hospital, Hofu,Yamaguchi, Japan, cDepartment of Radiology, Yamaguchi Univ, Ube,Yamaguchi, Japan

P163 Cognitive impairment in bipolar disorder: an endophenotype or a result of disease? A study in bipolar offspring E Mesman, MN Bhmer, MHJ Hillegers, WA Nolenb Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands, b Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands P164 Yoga as a complementary therapy for the improvement of quality of life in perinatal women with bipolar disorder A Nandaa, J Abizadehb,c, S Misrib,c a Faculty of Science, University of British Columbia, Vancouver, British Columbia, Canada, b Reproductive Mental Health Program, B.C. Childrens & Womens Hospital, Vancouver, Canada, c Department of Psychiatry, University of British Columbia, Vancouver, Canada P170 BDNF levels in first-degree relatives of patients with Bipolar Disorder: preliminary data MP Vasconcelos-Moreno,, M Kunz,, P Ferrari, IC Passos, J Bcker,, RK Burque, R Reckziegel, CS Gama,, F Kapczinski,, M Kauer-SantAnna, Faculty of Medicine, Department of Psychiatry, Universidade Federal do Rio Grande do Sul, Brazil, Rua Ramiro Barcelos, Porto Alegre, RS, Brazil, Bipolar Disorders Program, Molecular Psychiatry Laboratory, Hospital de Clnicas de Porto Alegre,Porto Alegre, RS, Brazil P173 State Related Alterations of gene Expression in Bipolar Disorder: A Systematic Review K Munkholma, M Vinberga, M Berkb,c,d, LV Kessinga a Psychiatric Center Copenhagen, Rigshospitalet, University of Copenhagen,Denmark, bDeakin University, School of Medicine, Barwon Health, Geelong, VIC, Australia, cOrygen Youth Health Research Centre, Centre of Youth Mental Health, University of Melbourne, Parkville, VIC, Australia, dMental Health Research Institute, Parkville, VIC, Australia P175 Neural correlates of trait personality in patients with mood disorders M Nakanoa, K Matsuoa, M Nakashimaa, K Egashiraa, T Matsubaraa, K Takahashib, N Matsunagac, Y Watanabea a Division of Neuropsychiatry, Department of Neuroscience, Yamaguchi University of Graduate School of Medicine, Yamaguchi, Japan, bKatakura Hospital, Yamaguchi, Japan, cDepartment of Radiology, Yamaguchi University of Graduate School of Medicine, Yamaguchi, Japan P176 Personality disorders in patients with mood disorders: are they stable over time? A. Nedic, O Zivanovic Department of Psychiatry and Medical Psychology, Medical School Novi Sad, Serbia

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

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P177 Met and unmet needs: evidence of significant health and social problems in Bipolar II Disorders from the MRC UK, ABC Cohort study J Nendicka, H Watkinsa, L Atkinsona, IN Ferriera, H grunzea, T Meyera and J Scotta,b a Institute of Neuroscience, Newcastle University, Newcastle-Upon-Tyne, United Kingdom,bUniversite de Paris Est, Creteil, (UPEC), France P178 gamma band neural synchronization deficits for auditory steady state responses in bipolar disorder Y Oda, T Onitsuka, R Tsuchimoto, S Hirano, N Oribe, T Ueno, Y Hirano, I Nakamura, S Katsuki, N Ohara, S Kanba Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan P179 Neuropsychological profiles of impulsivity in bipolar I and II disorders SH Oha, JS Changa, JH Parkb, JE Choic, JY Hera, YS Parka, TH Haa, K Haa a Department of Psychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea, b Department of Psychiatry, Seoul National University Hospital, Seoul, South Korea, cDepartment of Psychiatry, Seoul Metropolitan Eunpyeong Hospital, Seoul, South Korea P180 Support for the involvement of Calreticulin gene in the evolution of cognition in humans T Farokhashtiani, M Ohadi Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran P181 Cognitive impairment in first-episode bipolar I disorder: the processing speed hypothesis N Ojedaa,b, J Peaa, A garcaa, R Segarrab,c, JI Eguiluzb,c, J garcac, M gutirrezb,d a Department of Methods and Experimental Psychology, University of Deusto, Bilbao, Spain, b CIBERSAM, Consorcio de Investigacin Biomdica en Red en Salud Mental, Madrid, Spain, c Psychiatry Department, Hospital de Cruces, Baracaldo, Spain, dPsychiatry Department, Hospital Santiago Apostol, Vitoria, Spain P184 Psychiatric co-morbidity in migraine patients: the role of family history A Ortiza, P Cervantesb, g Slotnikc, C Slaneyd, J garnhamd, g Tureckib,e, C ODonovana, M Aldaa,b,f a Mood Disorders Program, Department of Psychiatry, Dalhousie University, Halifax, NS, Canada, b Department of Psychiatry, McGill University, Montreal, QC, Canada, cClinique de la Migraine a Montreal, Montreal, QC, Canada, dCapital District Health Authority, Halifax, NS, Canada e Douglas Mental Health University Institute, Montreal, QC, Canada, fDepartment of Psychiatry, 3rd Medical School, Charles University, Prague, Czech Republic

P186 Evaluation of first 50 patients in a bipolar disorder unit N Turhan, N zpoyraz, G Karaku, L Tamam Cukurova University, Faculty of Medicine, Department of Psychiatry, Adana, Turkey P189 Protein expression profiles in hippocampus of sleep-deprived mice, the manic-like animal model JW Paika, HJ Parkb, WS Kanga, EJ Kimc, JW Kima a Department of Neuropsychiatry, School of Medicine, Kyung Hee University, Seoul, Republic of Korea, bKohwang Medical Research Institute, School of Medicine, Kyung Hee University, Seoul, Republic of Korea, c Department of Neuropsychiatry, Eulji University School of Medicine, Seoul, Republic of Korea P192 Cognitive impairment in patients with bipolar disorder during depressive episodes R Paunescu, I Miclutia Department of Psychiatry, University of Medicine and Pharmacy Iuliu Hatieganu, Cluj Napoca, Romania P193 Phenomenology of First Episode Bipolar Affective Disorder A Nagarkara, N Shaha, S Sonavanea, A Purohitb, M Johnstonc, Y Bureaud, A Shrivastavae,f a LTM Medical College, University of Mumbai, India, bSt. Georges University, Grenada, West Indies, cUniversity of Toronto, Toronto, ON, Canada, dLawson Health Research Institute & The University of Western Ontario, London,ON, Canada, eMental Health Foundation of India (PRERANA Charitable trust) and Silver Mind Hospital, Mumbai, India, fThe University of Western Ontario, & Lawson Health Research Institute, London, Canada P194 Diagnostic variability amongst the minor bipolar disorders by classification systems A Nagarkara, S Sonavanea, N Shaha, A Purohitb, M Johnstonc, Y Bureaud, A Shrivastavae,f a LTM Medical College, University of Mumbai, India, bSt. Georges University, Grenada, West Indies, cUniversity of Toronto, Toronto, ON, Canada, dLawson Health Research Institute & The University of Western Ontario, London,ON, Canada, eMental Health Foundation of India (PRERANA Charitable trust) and Silver Mind Hospital, Mumbai, India, fThe University of Western Ontario, & Lawson Health Research Institute, London, Canada

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

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P195 Neurocognitive functioning prior to the first manic episode A Ratheesha, SJ Woodb,c, J Bettsd, W Brewerd, A Linc, d, M Berkd,f,g, B Nelsond, PD Mcgorrya,d, AR Yungd, A Bechdolf d,e a ORYGEN Youth Health, Melbourne, VIC, Australia, bMelbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, VIC, Australia, cSchool of Psychology, University of Birmingham, United Kingdom, dORYGEN Research Centre, Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia, eDepartment of Psychiatry and Psychotherapy, University of Cologne, Germany, fDeakin University, Geelong, VIC, Australia, gDepartment of Psychiatry, University of Melbourne, Melbourne, VIC, Australia P199 A Functional MRI investigation of the neural correlates of declarative and recognition memory in obese patients with Bipolar Diorder MR Restivoa,b, MC McKinnona,b, BN Freya,b, gB Halla,b, VH Taylora,c,d a Neuroscience Department, McMaster University, Hamilton, ON, Canada, bMood Disorder Program, St. Josephs Healthcare Hamilton, Hamilton, ON, Canada, cDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada, dPsychiatry Department, Womens College Hospital, Toronto, ON, Canada P202 Psychosocial functioning in first- versus multiple-episode bipolar patients AR Rosaa, I gonzlez-Ortegab, A gonzlez-Pintob, E Echeburab, M Comesa, A Martnez-rana, A Ugarteb, M Fernndezb, E Vietaa a Bipolar Disorders Program, Institute of Neurosciences, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain, bDepartment of Psychiatry, Santiago Apstol Hospital, University of the Basque, Country, CIBERSAM, Vitoria, Spain P205 Is serum matrix metalloproteinase-9 (MMP-9) related to staging in bipolar disorder? JK Rybakowskia, A Remlinger-Molendaa, A Czech-Kucharskaa, M Wojcickab, M Michalakc, J Losyb a Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland, b Department of Clinical Neuroimmunology, Poznan University of Medical Sciences, Poznan, Poland, cDepartment of Computer Science and Statistics, Poznan University of Medical Sciences, Poznan, Poland P207 The influence of emotional stimuli on time perception of manic patients V Ryu, SD Kook, HS Cho Department of Psychiatry, Konyang University, Daejeon, South Korea P212 Neurocognitive impairment of euthymic bipolar patients in a Chilean outpatient clinic: A crosssectional pilot study RF Sanchez, P Flores, J Aguirre, O Padilla, P Cumsille Bipolar Disorders Program, P. Catholic University of Chile, Santiago, Chile

P215 Suicide by overdose in a bipolar disorder cohort A Schaffera,b, M Sinyora,b, A Howlettb, A Cheunga,b a Mood and Anxiety Disorders Program, Sunnybrook Health Sciences Centre, Department of Psychiatry, University of Toronto, Toronto, ON, Canada, bDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada P216 Switch Rates from Unipolar Disorder to Bipolar Disorder and Associated Risk Factors: Results From a 2-year Naturalistic Follow-up F Seemller, S Dittmann, S Meyer, H Mller, M Riedel, E Severus a Department of Psychiatry, Ludwig-Maximilian-University Munich, Munich, Germany P217 A longitudinal study of fronto-limbic brain structures in patients with bipolar I disorder during lithium treatment S Seleka, b, M Nicoletti a, gB Zunta-Soares a, JP Hatchc, Fg. Neryd K Matsuoe, M Sanchesa, JC Soaresa a UT Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, TX, bPsychiatry Department, Harran University Faculty of Medicine, Sanliurfa, Turkey, cDepartments of Developmental Dentistry and Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, d Bipolar Disorder Research Program, Department of Psychiatry, University of Sao Paulo Medical School, Sao Paulo, Brazil, eDivision of Neuropsychiatry, Department of Neuroscience, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan P218 Several peripheral oxidative biomarkers in bipolar disorder S Seleka, A Altindagb, g Saracogluc, N Aksoyd, a Harran University Faculty of Medicine, Psychiatry Department, Sanliurfa, Turkey, bGaziantep University Faculty of Medicine, Psychiatry Department, Gaziantep, Turkey, cSanliurfa Teaching Hospital, Sanliurfa, Turkey, dHarran University Faculty of Medicine, Biochemistry Department, Gaziantep, Turkey P219 No impairmant on executive functions and memory in bipolar disorder over time V Senturka, H Demirelb, C Atbasoglua a Psychiatry, Ankara University, Faculty of Medicine, Ankara, Turkey, bPschology, Private, Ankara, Turkey P220 Comparisons of prevalence of catatonic symptoms and clinical characteristics between schizophrenia and bipolar disorder JM Seo, SH Shon, JS Lee, YH Joo University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Republic of Korea

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

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P221 Diagnostic conversion of major depressive disorder to bipolar disorder in pregnancy and postpartum V Sharmaa,b, B Xiec, K Campbelld, D Penavae, E Hampsonf, D Mazmaniang, C Popeh a Psychiatry and Obstetrics & Gynecology, University of Western Ontario, London, ON, Canada, b Perinatal Clinic, St. Josephs Health Care, London, ON, Canada, cDepartments of Obstetrics & Gynecology and Epidemiology & Biostatistics, University of Western Ontario, London, ON, Canada, dEpidemiology and Biostatistics, Obstetrics and Gynecology, and Paediatrics, University of Western Ontario, London, ON, Canada, eDepartment of Obstetrics and Gynaecology, London Health Sciences Centre, London, ON, Canada, fDepartment of Psychology and Graduate Program in Neuroscience, University of Western Ontario, London, ON, Canada, gPsychology, Lakehead University, Thunder Bay, ON, Canada, hRegional Mental Health Care, London, ON, Canada P224 COMT polymorphisms as predictors of cognitive dysfunction during manic and mixed episodes in bipolar I disorder Mg Soeiro-de-Souzaa, R Machado-Vieirab, DS Bioa, CM Do Pradob, RA Morenoa a Mood Disorders Unit GRUDA, Department and Institute of Psychiatry, School of Medicine, University of Sao Paulo (HC-FMUSP), bLaboratory of Neuroscience LIM-27, Department and Institute of Psychiatry, School of Medicine, University of Sao Paulo (HC-FMUSP) P226 Association between bipolar disorder and family history of psiquiatric disorders: an analysis of huwc patients database LA gurgel, EM Barros, CMF Ribeiro, NC Vasconcelos, WS gurgel, JRg Luna, AHS Carneiro, FgM Souza Affective Disorders Study Group, Department of Clinical Medicine, Federal University of Cear, Fortaleza, Brazil P227 Prevalence of depression among indigenous elders from the santo antnio pitaguary community Brazil KJN Matos, WS gurgel, PS Pantoja, AEC Filho, MEF Arago, DP Machado, CMF Ribeiro, FgM Souza Affective Disorders Study Group, Department of Clinical Medicine, Federal University of Cear, Fortaleza, Brazil P230 Interferon- induces nitric oxide synthase expression and heme oxygenase-1 down-regulation in microglia: Implications of IFN--induced mood disorders KP Sua,b,c, DY Lub, YM Leungb a Institute of Psychiatry, Kings College London, London, United Kingdom, bGraduate Institute of Neural and Cognitive Sciences, China Medical University, Taichung, Taiwan, cDepartment of Psychiatry and Mind-Body Research Center (MBI-Lab), China Medical University Hospital, Taichung, Taiwan

P231 Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins H Sugawaraa,b, K Iwamotoa,c, M Bundoa,c, J Uedaa, T Miyauchia, A Komoria, A Kazunoa, N Adatd, I Kusumie, Y Okazakif, J Ishigookab, T Kojimad, T Katoa a Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Institute, Saitama, Japan, bDepartment of Psychiatry, Tokyo Womens Medical University, Tokyo, Japan, c Department of Molecular Psychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan, dResearch Equipment Center, Hamamatsu University School of Medicine, Shizuoka, Japan, e Department of Psychiatry, Hokkaido University, Sapporo, Japan, f Tokyo Metropolitan Matsuzawa Hospital, Tokyo, Japan P235 The sociodemographic, clinical, temperament characteristics and childhood trauma of bipolar disorder compared to unipolar disorder Z N Tellioglua, D Tanb, F Karadagb, RP gokalpb a Psychiatry, Turhal State Hospital, Tokat, Turkey, bDepartment of Psychiatry, Maltepe University Faculty of Medicine, Istanbul, Turkey P236 A clinical study on bipolar disorder and the chronic depression H Tanakaa, T Owashia, M Hidab, S Yokoyamab, T Kumataa,c, I Kudoa,b a Showa University Fujigaoka Hospital, Yokohama, Japan, bShowa University Northern Yokohama Hospital, Yokohama, Japan, cHiyoshi Hosipital, Yokohama, Japan P238 Electrodermal hyporeactivity is a valid indicator of suicidal propensity in bipolar disorder M Wolfersdorfa, R Straubb, M Jandlc, J Steyerc, WP Kaschkac, LH Thorelld a Department of Psychiatry and Psychotherapy, State Hospital Bayreuth, Bayreuth, Germany, b Psycho-therapeutenkammer, Baden-Wrttemberg, Germany, cDepartment of Psychiatry I, University of Ulm, Zentrum fr Psychiatrie (ZfP), Suedwuerttemberg, Germany, dResearch and Development, Emotra AB, Linkping, Sweden P240 Comparison of the frontal function in bipolar disorder and major depressive disorder: nearinfrared spectroscopy study H Tomiokaa, A Yamamotob, AJ Motokib, H Kobayashia, B Yamagataa,c, H Otaa, H Tanakaa, M Mimura b a Department of Neuropsychiatry, Showa University School of Medicine, Tokyo, Japan, b Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan, cDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA, USA

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P241 Functioning in Remission Phase of Bipolar Disorder: A Controlled Study SN Traka, BM Alisirb, H Karadab, S rselb, H Trkaparb a Department of Psychiatry, Mut State Hospital,Mersin,Turkey, bDepartment of Psychiatry ,Dkap Yldrm Beyazt Training and Research Hospital, Ankara, Turkey P242 Differentiation between bipolar and major depressive disorders: a NIRS study N Tsujiia, H Akashia, S Sakaia, W Mikawaa, E Kirimea, O Shirakawaa Department of Neuropsychiatry, Kinki University Faculty of Medicine, Osaka-sayama, Osaka, Japan P244 Could continuous cycling pattern identify a specific type of bipolar disorder? A Tundo, F Marchetti, L Proietti, R De Filippis, R Necci Istituto di Psicopatologia, Rome, Italy P250 Effects of personality and gender on recognition of emotions in bipolar disorder E Vierck, RJ Porter, PR Joyce Department of Psychological Medicine, University of Otago, Christchurch, Christchurch, New Zealand P252 Self-report Predictors Distinguishing Bipolar Disorders from Borderline Personality PA Vhringera,b,c, K Alveara,d, S Medinaa, C Espinosaa, K Alexandrovica, P Riumalloa, F Leivaa, ME Hurtadoa, JF Cabreraa, M Sullivanc, NS Holtzmanc, SN ghaemi c a Unidad de Trastornos del nimo. Clnica Psiquitrica Universitaria. Hospital Clnico Universidad de Chile. Facultad de Medicina Universidad de Chile, Santiago, Chile, b Clnica de Trastornos del nimo. Instituto Psiquitrico Dr. Jos Horwitz B, Santiago, Chile, c Mood Disorder Program. Tufts Medical Center, Boston, USA, d Universidad Diego Portales, Santiago, Chile P253 Relationship between cognitive impairment and history of psychosis in bipolar disorder M Vrabiea, I Miclutiab,c, V Marinescua,d, C Popescuc, D Enachea a 7Ward,Clinical Hospital of Psychiatry Al. Obregia Bucharest, Romania, bDepartment of Psychiatry, University of Medicine & Pharmacy Iuliu Hatieganu Cluj-Napoca,Romania, cSecond Psychiatric Clinic, Emergency County Hospital Cluj-Napoca, Romania, dDepartment of Psychiatry, University of Medicine & Pharmacy Carol Davila, Bucharest, Romania P254 Assessment of neuropsychological functioning in euthymic bipolar disorder V Marinescua,b, M Vrabiea, D Enachea a 7Ward, Clinical Hospital of Psychiatry Al. Obregia Bucharest, Romania, bDepartment of Psychiatry, University of Medicine & Pharmacy Carol Davila, Bucharest, Romania

P260 Polarity change: is it predictable? O Zivanovic, A Nedic Department of Psychiatry and Medical Psychology, Medical School Novi Sad, Serbia

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

POSTER SESSION II
Friday, 16 March 2012 17.30 -19.00
*by surname alphabetic order

P11 Bipolar disorder, Substance Use and Violent behavior: What are the relationships? AR Rusdia, A Yeeb, gC Ngb, H Habila a University of Malaya Center for Addiction Sciences (UMCAS), University of Malaya, Lembah Pantai Kuala Lumpur, bDepartment of Psychological Medicine, Faculty of Medicine , University of Malaya, Lembah Pantai, Kuala Lumpur, Malaysia P14 Effects of concurrent pharmacotherapy on ECT applications and on maintenance following ECT MS Yldrm, Atagn, S Yeilyurt, D Yeilba, M Arslan, KF Yavuz, E Kurt Bakrky Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Istanbul, Turkey 5th Psychiatry Department P18 Bipolar Disorder in Current Practice: Analysis of a Multinational Observational Study (WAVEbd) with Turkish Recruitment Data* O Aydemira, V Senturkb, S Kesebirc, E Blasco-Colmenaresd, E Medinae on behalf of the WAVE-bd Study groupf a Celal Bayar University, Turkey, bAnkara University, Turkey, cErenkoy Psychiatry Research and Training Hospital, Turkey, dWelch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA, eAstraZeneca Pharmaceuticals, Madrid, Spain f WAVE-bd Advisory Board members: E Vieta [Chair] (Spain), F Bellivier (France), ML Figueira (Portugal), D Souery (Belgium), JM Langosch (Germany), *Study funded by AstraZeneca; Clinical Trials Registry: NCT01062607 P19 The frequency of dissociative symptoms and bipolar disorder comorbidity of patients with conversion disorder S Yayla, B Bakim, A zer, O Karamustafalioglu Sisli Etfal Research and Teaching Hospital, Psychiatry Clinic, Istanbul, Turkey P20 The frequency of adult attention-deficit hyperactivity and bipolar disorders in parents of ADHD children U Kolat, B Bakim, S Sertcelik, OA Ozer, O Karamustafalioglu Sisli Etfal Research and Teaching Hospital, Psychiatry Clinic, Istanbul, Turkey P21 Adult attention-deficit hyperactivity disorder of frequency in first-degree relatives of bipolar patients E Turkyilmaz, B Bakim, OA Ozer, O Karamustafalioglu Sisli Etfal Research and Teaching Hospital, Psychiatry Clinic, Istanbul, Turkey

P04 Frequency of antipsychotic drug using on long-term treatment of bipolar disorder C Akkayaa, g Deniza, S Cangurb, S Kirlia a Uludag University Medical Faculty, Psychiatry and b Biostatistics Departments, Gorukle, Bursa, Turkey P05 Adult Attention Deficiency-Hyperactivity Disorder with Bipolar Disorder: The good Clinical Outcomes of a Case with Stimulant treatment A Aksoy obana, D Eraslan ztrkb a Acibadem Fulya Hospital, Psychiatry Unit, Istanbul, Turkiye, bAcibadem University, Department of Psychiatry, Istanbul, Turkiye P06 Insights into the neurobiology of bipolar disorder from patients with comorbid epilepsy S Ali Assistant Professor, University of Toronto, Staff Psychiatrist, Neuropsychiatry, Toronto Western Hospital, Toronto, ON, Canada P07 Internalized stigma of individuals with bipolar disorder and schizophrenia M Alkan, C Grdal, O Kuman, G zg, A Eryavuz, S Vahip Ege University School of Medicine, Psychiatry Department, Izmir, Turkey P09 Lamotrigine as a Mood Stabilizer: Data from a Specialized Mood Clinic in Turkey D Yesilbas, S Yesilyurt, K Altnba Rait Tahsin Mood Clinic, Bakrky Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, Istanbul, Turkey P10 Low Rates of Alcohol Use Among Turkish Bipolar Patients: Cultural or genetic? K Altnbaa, EC Evrenb, ET Oralc a Rait Tahsin Mood Clinic, Bakrky Research and Training Hospital for Psychiatry, Neurology and Neurosurgery,Istanbul,Turkey, bAlcohol and Drug Use Disorders Treatment Center, Bakrky Research and Training Hospital for Psychiatry, Neurology and Neurosurgery,Istanbul,Turkey, c Department of Psychology, TC Istanbul Commerce University, Istanbul, Turkey

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P26 Psychiatric comorbidity of heroin and alcohol dependence and bipolar disorder treatment within Work-Occupational Therapy K Becir, R Perisic, M Vukotic, I Redzepagic Special Psychiatric Hospital Dobrota, Kotor, Montenegro P27 Differentiating between bipolar disorder type II and major depressive disorder S Begaa, A Schaffera,b, B goldsteina,b, A Levitta,b a Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada, bMood and Anxiety Disorders Program, Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada P30 Pharmacologic strategies used by Venezuelan psychiatrists in the treatment of Acute Manic Episodes in patients with Bipolar Disorder M Bifanoa,d, P Oropezab,d, M Ortegaa,c,d, A Pachecoa,d, M Camprubia,e a Central University of Venezuela, School of Medicine, Caracas, Venezuela, bDocent Medical Center La Trinidad, Caracas, Venezuela, cHumana Docencia. Caracas, Venezuela, dColegio Venezolano de Neuropsicofarmacologia, Caracas, Venezuela, eSwindon North and West Community Mental Health Team (CMHT), United Kingdom P31 Pharmacologic strategies used by Venezuelan psychiatrists in the treatment of Acute Depressive Episode in patients with Bipolar I and II Disorder M Ortegaa,c,d, P Oropezab, d, M Bifanoc,d, A Pachecoc ,d, M Camprubic ,e a Humana Docencia. Caracas, Venezuela, bDocent Medical Center La Trinidad. Caracas, Venezuela, c Central University of Venezuela, School of Medicine, Caracas, Venezuela, dColegio Venezolano de Neuropsicofarmacologia, Caracas, Venezuela, eSwindon North and West Community Mental Health Team (CMHT), United Kingdom P32 Scientometrics Study of Bipolar Disorder in Web of Science (2006-2010) MH Biglu, N Chakhmachi Paramedical Faculty, Tabriz University of Medical Sciences, Tabriz, Iran P41 Predictors of transition into bipolar disorder after the first lifetime depressive episode JD Bukh, LV Kessing Research Unit for Affective Disorders, Psychiatric Center Copenhagen, Rigshospitalet, Copenhagen, Denmark

P42 Varenicline-induced psychotic depressive episode in a patient with bipolar disorder B Burcak Annagura, Y Bezb a Selcuk University, Selcuklu Medical School, Department of Psychiatry, Konya, Turkey, bDicle University, Medical School, Department of Psychiatry, Diyarbakr, Turkey P46 Vitamin D deficiency or insufficiency in patients with bipolar disorder compared to health controls B Cha, YS Kim, BJ Kim, CS Lee, JW Sohn, CS Park Department of Psychiatry, Gyeongsang National University Hospital, Jinju, Korea P47 Integrating clinical impressions and symptomatic severity in depressed patients with bipolar disorders JS Changa, J Leeb, T Parkb, TH Haa, K Haa a Department of Psychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea, b Department of Statistics, Seoul National University, Seoul, South Korea P48 The metabolic syndrome in drug-nave bipolar II disorder patients and the influence of twelveweek pharmacological intervention on metabolic disturbances MH Chia, PS Chena,b,c a Department of Psychiatry, National Cheng Kung University Hospital, Dou-Liou Branch, Yun-Lin, Taiwan, bDepartment of Psychiatry, National Cheng Kung University Hospital, Tainan, Taiwan, c Department of Psychiatry, College of Medicine, National Cheng Kung University, Tainan, Taiwan P50 Artists In the Mood F elika, AD Baterzi ngb, g elikc, K Yazicib, A Yazici Ab, Tot Acarb a Dr. Ekrem Tok Adana Mental Health Hospital, Turkey, bUniversity Of Mersin School Of Medicine, Psychiatry Department, Turkey, cUniversity of ukurova School of Medicine, Child and Adolescent Psychiatry Department P51 gender differences in first episode mania SM Cottona, M Lambertb, M Berka,c,d, Bg Schimmelmanne, PD Mcgorrya, P Conusf a Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Melbourne, VIC, Australia , bPsychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Germany, cDeakin University, Geelong, VIC, Australia, dMental Health Research Institute, Parkville, VIC, Australia, eUniversity Hospital of Child and Adolescent Psychiatry, University of Bern, Switzerland, fTreatment and Early Intervention in Psychosis Program (TIPP), Dpartement de Psychiatrie CHUV, Universit de Lausanne, Clinique de Cery, Prilly, Switzerland

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P52 Regained control: Lived experience of patients suffering from bipolar disorder with a relapse prevention plan, a fenomenological study TH Daggenvoordeb, PJJ goossensa,b,c a Expertise Centre Health, Social Care and Technology, Saxion Universities of Applied Sciences, Deventer, The Netherlands, bCentre for Bipolar Disorders, Dimence Mental Health Care, Deventer, The Netherlands, cIQ Healthcare, 114, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands P53 Adding quetiapine to antidepressants in the depressive episode of bipolar disorder II case report IA Dan, O Serban, C Kapur Alexandru Obregia Clinical Psychiatry Hospital, Department 10, Bucharest, Romania P54 Bipolar Disorder in Women: a comparative study of Homeopathic treatment with Aurum metallicum, Natrum muriaticum and Ammonium carbonicum versus Tegretol C. De Rosa Eolas Irish Homeopathic Research Centre, Dept. of Clinica Research and Provings, Cork City, Ireland P59 The effects of psychodrama on depression among women with chronic mental disorder F Ebrahimi Belil, A Rahgoien, M Rahgozar Razi Psychiatry Hospital, Tehran, Iran P60 Evaluation of weight and metabolic parameters after switching from olanzapine to aripiprazole: a clinical case series of bipolar patients AC Ercan, K Altnba, E Kurt 5th Psychiatry Department, Bakrky Research and Training Hospital for Psychiatry Neurology and Neurosurgery, Istanbul, Turkey P61 A case report on treatment of bipolar disorder of 10 Years via faradarmani E Esmaeili, F Ashrafi-Amineh, S Saie Joeghan Association of Faradarmani, Tehran, Iran P64 Affective temperament characteristics and bipolar disorder comorbidity in obsessive compulsive disorder N Fistikcia, M Hacioglua, S Ereka, A Tabub, E Ertena, O Saatcioglua a Bakrkoy Prof. Dr. Mazhar Osman Hospital of Mental Health and Neurology, 3.Psychiatry clinic, stanbul, Trkiye, bBakrkoy Prof. Dr. Mazhar Osman Hospital of Mental Health and Neurology, Clinic of Neurosis, stanbul, Trkiye

P65 Cognitive style in bipolar II disorder K Fletcher, g Parker, V Manicavasagar School of Psychiatry, Black Dog Institute, University of New South Wales, Sydney, NSW, Australia P69 Drugs not included in the bipolar disorder treatment guidelines N Freund, M Blanco, P garca, C Harkous, C Bonilla Department of Psychiatry, Hospital Universitario Prncipe de Asturias, Alcal de Henares, Espaa P71 Delay in Bipolar Disorder Treatment is Correlated to an Adverse Course of Illness PD goia, LE Silveiraa, MF Vianna-Sulzbacha, RK Burquea, RF Reckziegela, BW Aguiara, B Pfaffensellera, KMM Cereserb, F Kapczinskib, MK SantAnnab, CS gamab a Bipolar Disorder Program and Laboratory of Molecular Psychiatry ,Hospital de Clnicas de Porto Alegre, Porto Alegre, Brazi, bHospital de Clnicas de Porto Alegre, and INCT for Translational Medicine, Porto Alegre, Brazil P75 Electroconvulsive therapy in bipolar disorder P garca, N Freund, C Harkous, B De Diego, g Morn Department of Psychiatry, Hospital Universitario Prncipe de Asturias, Alcal de Henares, Spain P76 Smoking and bipolar disorder P garca, N Freund, C Harkous, B De Diego, L Marinas Department of Psychiatry, Hospital Universitario Prncipe de Asturias, Alcal de Henares, Spain P77 Recognising bipolar disorder in patients with PTSD a case report B geerling, AWMM Stevens Dimence Centre for Bipolar Disorders, Almelo, The Netherlands P82 The effects of manic and depressive symptoms on the circadian rhythmicity of activity levels in bipolar disorder R gonzaleza, M Tohena, C Tammingab, T Suppesc a University of Texas Health Science Center San Antonio, San Antonio, TX, USA, bUniversity of Texas Southwestern Medical Center, Dallas, TX, USA, cStanford University School of Medicine, Palo Alto, CA, USA

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P84 Do Contemporary Maintenance Treatment Study Designs in Bipolar Disorder Demonstrate that Atypical Antipsychotics are Mood Stabilizers? FK goodwina, SN ghaemib a George Washington University Medical Center, Washington, DC, USA, bTufts Medical Center, Mood Disorders Program, Boston, MA, USA P85 Recognizing prodromes of manic or depressive recurrence in outpatients with bipolar disorder: a cross-sectional study PJJ goossensa,b,c, RW Kupkad,e,TAA Beentjesb, T van Achterbergc a Expertise Centre Health, Social Care and Technology, Saxion Universities of Applied Sciences, Deventer, The Netherlands, bCentre for Bipolar Disorders, Dimence Mental Health Care, Deventer, The Netherlands, cIQ Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands d VU GGZ Ingeest, Amsterdam, The Netherlands, eBipolar Disorders Treatment Program, Altrecht Institute for Mental Health Care, Utrecht, The Netherlands P92 Subjective experiences of offspring of bipolar patients: from memories of childhood to attitudes and behavioural patterns in adulthood C gurdal, O Kuman, M Alkan, S Vahip, I Vahip Ege University, Faculty of Medicine Department of Psychiatry, Affective Disorders Unit, Izmir, Turkey P98 Bipolar disorder comorbidity and affective temperament in panic disorder M Hacioglua, NFistikcia, E Ereka, A Tabub, E Ertena, O Saatcioglua a Bakrkoy Prof. Dr. Mazhar Osman Hospital of Mental Health and Neurology, 3.Psychiatry clinic, stanbul, Trkiye, bBakrkoy Prof. Dr. Mazhar Osman Hospital of Mental Health and Neurology, Clinic of Neurosis, stanbul, Trkiye P100 A prospective study of activation syndrome induced by antidepressants T Haradaa, K Inadab, K Yamadaa, K Sakamotob, J Ishigookab a Department of Psychiatry, Tokyo Womens Medical University Medical Center East, Tokyo, Japan, b Department of Psychiatry, Tokyo Womens Medical University, Tokyo, Japan P101 Therapeutic drug monitoring of risperidone in bipolar disorder: a case report Fg Hizli Sayara, S Ozilhan b , N Tarhana a Uskudar University, Istanbul, Turkiye, bNPIstanbul Neuropsychiatry Hospital , Istanbul, Turkiye

P104 Anthropometric parameters in neonates exposed prenatally to lithium or polytherapy ML Imaza, A gonzalezb, D Hidalgob, M garciab, A Torresa, C Hernndezc, Ll garcia-Estevea,d a Perinatal Psychiatry and Gender Research Program, Psychiatry Department, Institut of Neuroscience, Hospital Clnic, Barcelona, Spain, bPsychiatry Department, Institut of Neuroscience, Hospital Clnic, Barcelona, Spain, cPsychiatry Department, Hospital Parc Tauli, Sabadell, Spain, dIDIBAPS, Hospital Clnic, Barcelona, Spain P106 Postdischarge suicides of inpatients with bipolar disorder in Finland in 1987-2003 Erkki Isometsa,b, Reijo Sundb, Kristian Wahlbeckb, Sami Pirkola a,b a Department of Psychiatry University of Helsinki, Helsinki, Finland, bDepartment of Mental Health and Substance Use Services, National Institute for Health and Welfare, Helsinki, Finland P107 Electronic self-monitoring of patients with bipolar disorder AS Jacobya, M Faurholt-Jepsena, M Vinberga, M Frostb, J Bardramb, L Kessinga a Department of Affective Disorders, Psychiatric Center Copenhagen, Rigshospitalet, University of Copenhagen, Denmark, bIT University, Copenhagen, Denmark P110 Quetiapine for manic-like symptoms in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome KS Na, SI Lee, Sg Kim, HY Jung Department of Psychiatry, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea P111 Lithium monotherapy and metabolic syndrome A gen, T Kaleliolu, A Tademir, ES Gen, zver, D Yeilba, K Altnba, E Kurt Bakrky Research and Training Hospital for Psychiatry, Neurology& Neurosurgery, Istanbul, Turkey P113 Significance of homocysteine to the risk cardiovascular in bipolar disorder F Kapczinski, F Chiarani, JF Tramontina, KM Cereser, L Stertz, C gubert, C Vargas, A Sitta, ATS Wyse Molecular Psychiatry Laboratory, Hospital de Clnicas de Porto Alegre (HCPA), Porto Alegre (RS), Brazil P115 Clinical characteristics and pattern of drug use in a population of crack cocaine users with and without mood disorders J Narvaez, CS gama, M Kauer-SantAnna, M Kunz M, F Kapczinski Laboratrio de Psiquiatria Molecular, Hospital de Clnicas de Porto Alegre, Porto Alegre, Brazil

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P116 A placebo-controlled, double-blind study of the efficacy and safety of aripiprazole for the treatment of acute manic or mixed episodes in Asian patients with bipolar I disorder (The AMAZE Study) H Kawasakia, S Kanbaa, T Kurokib a Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, bNational Hospital Organization, Hizen Psychiatric Center, Saga, Japan P118 A Comparison Before and After Using Lamotrigine In Long Term Continued Treatment: The Effect of Blood Level Sermin Kesebira, Fisun Akdenizb, Aysun Demira, Mustafa Bilicia a Erenkoy Psychiatry Training and Research Hospital, Istanbul, Turkey bEge University, Psychiatry Department, Izmir, Turkey P119 gender specific sexual adverse effects and hormonal variables in bipolar patients: A comparison between lithium, quetiapine, and olanzapine S Kesebir, B Toprak, B Baykaran, A Hariri Erenkoy Training and Research Hospital for Mental and Neurologic Disorders, stanbul, Turkey P120 Diabetes in first episode mania: relations with clinical and the other endocrinological and metabolic parameters Ag gencer, S Kesebir Erenkoy Training and Research Hospital for Mental and Neurological Disorders, Istanbul, Turkey P121 The Relationship of Internalized Stigmatization in Bipolar Disorder With Quality of Life and Treatment Compliance MF Ustundag, S Kesebir Erenkoy Training and Research Hospital for Mental and Neurological Disorders, Istanbul, Turkey P122 The effects of centralised and specialised outpatient intervention versus standard treatment in the early course of bipolar disorder: a randomised clinical trial LV Kessing Psychiatric Centre Copenhagen, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

P130 Psychometric differences of hallucinatory experiences in psychotic and nonclinical population Y Kima, HY Jungb, JS Changc, SS Hwangd, SH Kime, YS Kime a Department of Adolescent Psychiatry, Seoul National Hospital, Seoul, Republic of Korea, b Department of Psychiatry, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea, c Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea, dInterdisciplinary Study in Brain Science, Seoul National University, Seoul, Republic of Korea eDepartment of Neuropsychiatry, Seoul National University Hospital, Seoul, Republic of Korea P132 An unexpected ultrasonographic finding in lithium treated patients: Peripyramidal hyperechogenity O Kumana, F Akdeniza, SS Ozbekb, g Kavukcub, g Unal-Kocabasc a Ege University, School of Medicine, Psychiatry Department, Izmir, Turkey, bEge University, School of Medicine, Radiology Department, Izmir, Turkey,cEge University, School of Medicine, Endocrinology Department, Izmir, Turkey P133 Thyroid abnormalities in lithium treated bipolar patients: A cross sectional study with healthy controls O Kumana, F Akdeniza, SS Ozbekb, g Kavukcub, g Unal-Kocabasc a Ege University, School of Medicine, Psychiatry Department, Izmir, Turkey, bEge University, School of Medicine, Radiology Department, Izmir, Turkey,cEge University, School of Medicine, Endocrinology Department, Izmir, Turkey P134 Bipolar disorder treatment: implications from the staging model perspective LE Silveiraa, PD goia, MF Vianna-Sulzbacha, AR Rosab, BS Panizzuttia, gR Friesa, M Kunza, CS gamac, F Kapczinskic, M Kauer-Santannac a Bipolar Disorder Program and Laboratory of Molecular Psychiatry ,Hospital de Clnicas de Porto Alegre, Porto Alegre, Brazil, bHospital Clinic of Barcelona, Psychiatry Department, Barcelona, Spain, cHospital de Clnicas de Porto Alegre, and INCT for Translational Medicine, Porto Alegre, Brazil P136 Antipsychotic and antidepressant associations: Effectiveness retrospective study in a psychiatric hospitalization unit AI Ledo Rubio, I Muoz, JJ de la gndara, H Hernandez Herrero, A de Dios, C Deza, L Minguez, B Pelaez Psychiatry, Divino Valles Hospital, Burgos, Spain

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P141 Valproate Plus Quetiapine Combination Therapy in Maintenance Treatment of Bipolar Disorder Contributes More Improvement than Either Used Alone CT Lia,b,d, TP Sua,b,d, JC Hsiehb,e, SJ Wangc, YM Baia,d, WC Lina, CC Lana a Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan, bInstitute of Brain Science, National Yang-Ming University, Taipei, Taiwan, cDepartment of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, dDivision of Psychiatry, Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan, eLaboratory of Integrated Brain Research, Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan P142 Adjunctive methylphenidate therapy for patients with treatment-resistant bipolar depression MR Lim, JS Chang, SY Lee, YS Park, TH Ha, K Ha Department of Psychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea P145 Prescription patterns in bipolar disorder women LS Lorenzoa, gH Vzquezb, RM Zaratieguia a Psinapsys Psychiatric Private Center, La Plata, Argentina, bDepartment of Neuroscience, University of Palermo, Buenos Aires, Argentina P146 The International Mood Network (IMN): A network created to foster research and improve practice in the treatment of depressive and bipolar illnesses H Lvdahla, E Correab, A Patkarc, C Paed, S Strejileviche, SN ghaemif a Srlandet Hospital, Arendal, Norway, bUniversity of Chile, Santiago, Chile, cDuke University, Durham, NC, USA, dCatholic University of Korea, Seoul, Korea, eFavoloro University, Buenos Aires, Argentina, fTufts Medical Center, Boston, MA, USA P150 Risk of recurrence of bipolar disorder in postpartum periods: a retrospective study of 374 females patients g Maina, g Rosso, A Aguglia, F Bogetto Mood and Anxiety Disorders Unit, Department of Neuroscience, University of Turin, Turin, Italy P154 Treatment-Resistant Bipolar Depression (TRBD): definition and therapeutic strategies M Massona, C Henryb a Clinique du Chteau, Garches, France, bCentre Expert Bipolaire, Crteil, France

P156 Interest of multifamiliy psychoeducation groups K Mbailaraa,b,f, L Zanouyb,f, S gardb,f, I Minoisb,f, A Desageb,f C Henryc,d,f a Laboratory of Psychology, EA4139, University Bordeaux Segalen , 3ter place de la Victoire, Bordeaux, France,bHospital Charles Perrens, Bordeaux, France, cAP-HP, Henri Mondor-Albert Chenevier Hospitals, Department of Psychiatry, Creteil, France, dINSERM, U 955, IMRB, dept of Genetics, Psychiatry Genetics, Creteil, France, eUniversity of Paris 12, France, fFondation FondaMental, Crteil, France P157 Reproductive characteristics of female outpatients of childbearing age with affective disorders M Marinellia, LS Lorenzob, R Zaratieguib a APSA Faculty (Asociacin de Psiquiatras Argentinos), Buenos Aires, Argentina, bPsinapsys Psychiatric Private Center, La Plata, Argentina P160 Employment outcomes in people with Bipolar Disorder: A systematic review S Marwahaa, A Durranib, SP Singha a Division of Mental Health, Warwick Medical School, University of Warwick, Coventry, United Kingdom, bNHS Lanarkshire, Motherwell, United Kingdom P162 Bipolar Disorder and Eating Disorder: a frequent comorbidity involving several treatment concerns M Mauri, C Cargioli Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Pisa, Tuscany, Italy P165 Efficacy of life skills training on reducing depressive symptoms in student population SM Mirzamania, F Azvarb, B Dolatshahic, A Asgarid a Department of Counseling, Islamshahr Branch, Islamic Azad University, Islamshahr, Iran, b University of Social Welfare & Rehabilitation Sciences, Tehran, Iran, cUniversity of Social Welfare & Rehabilitation Sciences, Tehran, Iran, dUniversity of Social Welfare & Rehabilitation Sciences, Tehran, Iran P167 Breaking bad news in bipolar disorders: an interview study of patients and physicians S.Montela,b, E Spitz,b University Paul Verlaine of Metz, France, bLaboratory APEMAC, Paris, Nancy, Metz, France

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

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P168 Coping strategies for stressful situations in remitted bipolar patients SH Junga, E Moona, JM Parka,b, BD Leea, YM Leea, YI Chungb,c, MS Junga a Department of Psychiatry, Pusan National University Hospital, Busan,South Korea, bDepartment of Psychiatry, Pusan National University School of Medicine, Yangsan, South Korea, cDepartment of Psychiatry, Pusan National University Yangsan Hospital,Yangsan, South Korea P169 Psychoeducation Efficacy and Symptomatic and Functional Recovery in Severe Bipolar Disorder KB Pellegrinellia, LO Costaa, KI Silvalb, VV Diasa,c, M Rosoa, M Bandeira b, RA Morenoa a Mood Disorders Unit (GRUDA), Department and Institute of Psychiatry, Clinicas Hospital, University of Sao Paulo, School of Medicine, Sao Paulo, Brazil, bLAPSAM Laboratrio de Sade Mental, Universidade Federal de So Joo del Rei, Minas, Gerais, Brazil, cBipolar Disorder Research Program, Hospital Santa Maria, Faculty of Medicine, University of Lisbon, (FMUL), Portugal P171 The Lifetime Prevalence of Bipolar Disorders and the use of Antidepressant Drugs in Bipolar Depression in Italy* MF Moroa,b, E Agugliab, M Balestrierib, JR Calabresec, F Caracib, L DellOssob, MC Hardoya,b, g Di Sciasciob, F Dragob, C Faravellib, ME Leccaa,b, M Nardinib, g Palumbob, Mg Cartaa,b a Department of Public Health, University of Cagliari, Cagliari, Italy, bAIFA group, Italy, cDepartment of Psychiatry, Case Western Reserv University, Cleveland, OH, USA, *This study was supported by a grant of AIFA (Agenzia Italiana del Farmaco) Number FARM54S73S, approved in 2005. P172 Sub-threshold depression and antidepressants use in a community sample: searching anxiety and finding bipolar disorder* ME Leccaa,b, MF Moroa,b, g Muraa,b, L Tondoc, M Balestrierib, F Caracib, L dellOssob, g Di Sciasciob, C Faravellib, MC Hardoya,b, KM Bhatd, M Casacchiab, F Dragob, g Mellinoa,b, Mg Cartaa,b a Department of Public Health, University of Cagliari, Cagliari, Italy, bAIFA group, Italy, cDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA, dDepartment of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX, USA, * This study was supported by a grant of AIFA (Agenzia Italiana del Farmaco) Number FARM54S73S, approved in 2005 P174 Clinical data on co-morbid bipolar symptoms in patients with Internet Addiction KW Mller, K Wlfling Outpatient Clinic for Behavioral Addictions, University Medical Center Mainz, Germany

P182 Differential clinical characteristics of prescription of lithium vs valproate: What do clinicians expect for lithium and valproate? T Owashia, H Tanakaa, M Hidab, S Yokoyamab, T Kumataa,c, I Kudoa,b a Showa University Fujigaoka Hospital, Yokohama, Japan, bShowa University Northern Yokohama Hospital, Yokohama, Japan, cHiyoshi Hospital, Yokohama, Japan P183 Lamotrigine for adults with Bipolar II Disorder and comorbid Attention Deficit/Hyperactivity Disorder: a case series B nca, M Akncb, S Karatoprakb a Department of Psychiatry, Faculty of Medicine, Ankara University, Ankara, Turkey, bChild and Adolescent Psychiatry Clinic, Dr. Sami Ulus Women and Children Hospital, Ankara, Turkey P185 Can Clinical Features Determine Long Term Monotherapy Lithium Response? A zerdema, Aydemirb, C Akkayac, S Kesebird, K Altinbase, Yenilmezf, Z Ersoya, AD Basterzig, Yildizh, Z Tuncaa a Department of Psychiatry, Faculty of Medicine, Dokuz Eylul University, Izmir,Turkey, bDepartment of Psychiatry, Faculty of Medicine, Celal Bayar University, Manisa, Turkey, cDepartment of Psychiatry, Faculty of Medicine, Uluda University, Bursa, Turkey, dErenkoy State Mental Hospital, Istanbul, Turkey, eRasit Tahsin Mood Disorders Unit, Prof. Dr. Mashar Osman Mental Health Training and Research Hospital, stanbul, Turkey, fDepartment of Psychiatry, Faculty of Medicine, Osmangazi University, Eskiehir, Turkey, gDepartment of Psychiatry, Faculty of Medicine, Mersin University, Mersin, Turkey, hDepartment of Psychiatry, Faculty of Medicine, Hacettepe University, Ankara, Turkey P187 Efficiency of long term prophylactic treatment in bipolar disorder MZ Erolu, N zpoyraz, G Karaku, L Tamam Cukurova University, Faculty of Medicine, Department of Psychiatry, Adana, Turkey P188 Assessment of Axis II burden in a sample of patients affected by Bipolar Disorder B Pacciardia, C Cargiolia, S Bellia, B Cotugnoa, M Di Fiorinob, M Mauria a Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Pisa, Italy, bVersilia Hospital, Lucca, Italy P190 The prevalence of metabolic syndrome in Korean patients with bipolar disorder KJ Parka, JS Leea,b, YH Joo a,b a Department of Psychiatry, Asan Medical Center, Seoul, South Korea, bDepartment of Psychiatry, University of Ulan College of Medicine, Seoul, South Korea

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P191 Concordance with treatment guidelines for bipolar disorder S Paterniti, JC Bisserbe University of Ottawa, Department of Psychiatry, Royal Mental Health Centre, Mood Disorders Program, Ottawa, Canada P196 Clinical predictors of response versus non-response to risperidone: CgI-21 scores after one week of treatment in a bipolar disorder population with co-occurring panic disorder or generalized anxiety disorder BJ Raudabaugha, JM Hernandeza, JS Seoa,b,c, K Jamison, V Cosgrovea,b, IS gwizdowskia, H Yanga,b, DV Sheehand, SL McElroye,f, T Suppesa,b a VA Palo Alto Health Care System, Palo Alto, CA, USA, bDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA, cDepartment of Psychiatry, College of Medicine, Konkuk University, Chung-ju Hospital, South Korea, dUniversity of South Florida, USF Institute for Research in Psychiatry, Tampa, FL, USA, eResearch Institute, Lindner Center of HOPE, Mason, Ohio, USA, fDepartment of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA P197 Prevalence of hypercalcemia in lithium-treated patients with bipolar disorder EJ Regeera, BA Twigtb, BM Houwelingb, IHM Borel Rinkesb, gD Valkc, MR Vriensb, RW Kupkaa,d a Altrecht Institute for Mental Health Care, Utrecht, The Netherlands, bDepartment of Surgery, University Medical Center Utrecht, The Netherlands, cDepartment of Endocrinology, University Medical Center Utrecht,The Netherlands, dDepartment of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands P198 Treatment of Bipolar Disorder in the Netherlands and concordance with treatment guidelines JW Renesa, EJ Regeera, WA Nolenb, RW Kupkaac a Altrecht Institute for Mental Health, Utrecht, The Netherlands, bUniversity Medical Center, University of Groningen, Groningen, The Netherlands, cVU University Medical Center, Amsterdam, The Netherlands P200 A review of services for bipolar disorder offered by Community Mental Health Teams (CMHT) in Vancouver, Canada VL Reynolds Pacific Bipolar Foundation, Vancouver, BC, Canada P203 Pharmaco-epidemiology of dually diagnosed US veterans with bipolar disorder RA Rosenheck VA New England Mental Illness, Research, Education and Clinical Center; Yale Medical School, West Haven, CT, USA

P204 Intramuscular Aripiprazole in Mania Clinical experience in the UK B Roya, M Bienrothb a Department of Psychiatry, South London and Maudsley NHS Trust, London, United Kingdom, b Department of Psychiatry, Oxleas NHS Foundation Trust, Bromley, United Kingdom P206 Hypomania Checklist and postpartum depression D Dudeka,b, M Siweka,b, R Jaeschkea, g Maczkaa, JK Rybakowskic a Department of Adult Psychiatry, Collegium Medicum, Jagiellonian University, Cracow, Poland, b Institute of Pharmacology, Polish Academy of Sciences, Cracow, Poland, cDepartment of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland P208 Lithium and tamoxifen modulates gsk-3 changes in striatum of rats induced by d-amphetamine in an animal model of mania J Quevedoa, SS Valvassoria, KC Cechinela, RB Varelaa, J Lopes-Borgesa, g da Luzb, MF Vittob, CT Souzab a Laboratory of Neurosciences and National Institute for Translational Medicine (INCT-TM), Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Cricima, SC, Brazil, bExercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Cricima, SC, Brazil P209 Substance use disorders among Iranian bipolar inpatients S Mehdi Samimi Ardestani, K Razjouyan, N Ramezani Department of Psychiatry, Shahid Beheshti University of Medical Science, Imam Hossein Medical Center, Behavioral Research Center, Tehran, Iran P211 Bipolar disorder (BD) presented with personality disorder (PD) comorbidity: A prevalence preliminary study R Sancheza, P Petersb, J Cerdaa, P Dagninoa, V Bagladib a Bipolar Disorders Program, Department of Psychiatry, P. Catholic University of Chile, Santiago, Chile, bPsychology School, P. Catholic University of Chile, Santiago, Chile P213 Clinical features of bipolar disorder (BD) subjects in a Chilean specialist outpatient clinic RF Sanchez, V Capponi, R Torres, O Padilla, J Aguirre, M Rufatt, P Cumsille Bipolar Disorders Program, P. Catholic University of Chile, Santiago, Chile

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P214 Co-morbidity and psychiatric family history in bipolar disorder (BD) from a Chilean specialist outpatient clinic RF Sanchez, P Flores, F Silva, O Padilla, M Said, A girardi, V Capponi Bipolar Disorders Program, P. Catholic University of Chile, Santiago, Chile P222 Revisiting the association between endometriosis and bipolar disorder V Kumara, M Khanb, gA Vilosc, V Sharmad,e a Department of Medicine, University of Toronto, Toronto, ON, Canada, bMood Disorders Program, Regional Mental Health Care, London, ON, Canada, cSt. Josephs Health Care, Department of Obstetrics and Gynaecology, The University of Western Ontario, London, ON, Canada, d Department of Psychiatry and Obstetrics & Gynaecology, University of Western Ontario, London, ON, Canada, ePerinatal Clinic, St. Josephs Health Care, London, ON, Canada P223 A Randomized, Double Blind, Placebo-Controlled Study of Adjunctive Quetiapine SR in the Treatment of Mixed States (MS) in Bipolar Disorder (BD) Singh V, Bowden CL University of Texas Health Science Center at San Antonio, San Antonio, TX, USA P225 Atypical antipsychotic use in Bipolar Disorder treatment: Results from the HARMONY study D Sourya, K Audenaertb, A Vankeirsbilckc, T Vanlerberghec a Psy-Pluriel, European Centre for Psychological Medicine, Brussels, Belgium, bDepartment of Psychiatry & Medical Psychology, University Hospital Ghent, Ghent, Belgium, cMedical Affairs, AstraZeneca, Brussels, Belgium P228 Factors associated to mood disorders during pregnancy in Brazilian Indian women FgM Souza, KJN Matos, WS gurgel, PS Pantoja, BH Sampaio, MEF Arago, VBN Souza Affective Disorders Study Group, Department of Clinical Medicine, Federal University of Cear, Fortaleza, Brazil P229 BIPOLAR and becoming or being pregnant, what to do? AWMM Stevens, B geerling, RBA Wissink Dimence, Mental Health Organisation, Deventer, the Netherlands

P232 Pharmacological treatment of bipolar depression: qualitative review of double-blind randomized clinical trials L Spanemberga, R Massudaa, L Lovatoa, L Paima, E Varesa, CS gamab, M Kauer-SantAnnab, M Sulzbacha, NS Rochaa, KMM Ceresrb a Post-Graduation Program in Psychiatry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil, bINCT Translational Medicine, Hospital de Clnicas de Porto Alegre, Porto Alegre, Brazil P237 Suicidality in bipolar affective disorder: The nature of impulsivity and impulse control disorders - A cross sectional controlled study K Thangavelu, R Howard, R Morriss Division of Psychiatry, University of Nottingham, Nottingham, United Kingdom P239 Impulsivity in bipolar disorder and co-occurring alcohol dependence: relationship to current versus past alcohol use BK Tolliver, JJ Prisciandaro, Dg Brown Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston SC, USA P245 POST-PARTUM Bipolarity: Missed and Dismissed. B J Turnera, R Lyndonb a Consultant Child and Family Psychiatrist, Visiting Medical Officer, Western Local Health District, New South Wales, Australia,b Clinical Senior Lecturer, University of Sydney, Australia P246 Adherence and depression in bipolar patients with suicidal risk A Ugarte, M Martinez-Cengotitabengoa, S Alberich, M Senz, M Karim, A gonzlez-Pinto CIBER Center of Mental Health, Santiago Apstol Hospital, Osakidetza, Vitoria, Spain, Stanley Research Center (03-RC-003), Biobanc, Santiago Apstol Hospital, Vitoria P247 Towards an educational theory of self-management for outpatients with a bipolar disorder: a stratified phenomenological and hermeneutical study design from the Netherlands SCgH van den Heuvela, PJJ goossensa,b,d, C Terlouwc, T van Achterbergd a Saxion University of Applied Sciences, Expertise Centre for Health, Social Care and Technology, Deventer, the Netherlands, bDimence, Institute for Mental Healthcare, Specialist Centre for Bipolar Disorders, Deventer the Netherlands, cSaxion University of Applied Sciences, Expertise Centre for Educational Innovations, Enschede, the Netherlands, dRadboud University Medical Centre, Nijmegen Centre for Evidence Based Practice, Nijmegen, the Netherlands

5TH BIENNIAL CONFERENCE OF THE INTERNATIONAL SOCIETY FOR BIPOLAR DISORDERS

14 - 17 MARCH 2012 / ISTANBUL - TURKEY

P248 From self-care to hospitalization: bipolar patients health care practices in Mexico I Vargas-Huicocheaa, S Berenzon-gornb a Psychiatry and Mental Health Department, Faculty of Medicine, Universidad Nacional Autonoma de Mexico, UNAM, Mexico City, Mexico, bEpidemiological and Social Research Department, Instituto Nacional de Psiquiatria Ramon de la Fuente Mexico City, Mexico P249 Bipolar disorder: patients perceptions of people attitudes I Vargas-Huicocheaa, S Berenzon-gornb a Psychiatry and Mental Health Department, Faculty of Medicine, Universidad Nacional Autonoma de Mexico, UNAM, Mexico City, Mexico, bEpidemiological and Social Research Department, Instituto Nacional de Psiquiatria Ramon de la Fuente Mexico City, Mexico P251 Outcomes and treatment practices in bipolar disorder: results from a large multinational longitudinal study (WAVE bd)* E Vietaa, ML Figueirab, F Bellivierc, D Soueryd, E Blasco-Colmenarese, JM Langoschf, M Moreno-Manzanarog, MA gonzalezh on behalf of the WAVE-bd Study group a Bipolar Disorders Programme, Hospital Clnic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain; bPsychiatric Department, Hospital Santa Maria, Faculty of Medicine, University of Lisbon, Lisboa, Portugal; cHpital Henri Mondor, Ple de Psychiatrie, Crteil cedex, France; d Centre Europen de Psychologie Mdicale / Psy-Pluriel, Brussels, Belgium; eWelch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; fBethanien Hospital for Psychiatry, Psychosomatics, and Psychotherapy, Greifswald, Germany; gMedical Department, AstraZeneca Pharmaceuticals, Madrid, Spain; hQuintiles, Madrid, Spain, * Study funded by AstraZeneca; Clinical Trials Registry: NCT01062607. P255 Investigating Impulsivity in Bipolar II Disorder: More state than Trait? HB Watkins, J Nendick, L Atkinson, IN Ferrier, H Grunze, J Scott, TD Meyer a Academic Psychiatry, Newcastle University, Newcastle upon Tyne, United Kingdom, bClinical Psychology, Newcastle University, Newcastle upon Tyne, United Kingdom P256 Alexithymic features among bipolar affective disorder patients O Ylmaz Psychiatry Service, Sarkam Military Hospital, Kars, Turkiye

P257 Correlation of selective serotonin reuptake inhibitor (SSR) use, weight gain and metabolic parameters A Yosmaoglua, N Fistikcib, M Hacioglub, A Keyvanc, O Saatcioglub, K Korad a Caycuma State Hospital, Psychiatry Clinic, Zonguldak, Trkiye, bBakrkoy Prof. Dr. Mazhar Osman Hospital of Mental Health and Neurology, 3.Psychiatry clinic, stanbul, Trkiye, cBakrkoy Prof. Dr. Mazhar Osman Hospital of Mental Health and Neurology, Adolescent Psychiatry Clinic, stanbul, Trkiye, dMarmara University Pendik Hospital of Education and Research, Psychiatry Clinic, stanbul, Trkiye P258 Changes in mania features among Iranian bipolar inpatients gh Zahed, M Samimi Shahid Beheshti University of Medical Science, Imam Hossein Hospital, Behavioral Science Research Center, Tehran, Iran P259 Herbal medicine and acupuncture for unipolar and bipolar depression: randomized controlled trials ZJ Zhang School of Chinese Medicine, LKS Faculty of Medicine, the University of Hong Kong, Hong Kong, China P261 Depression: Does it affect the comprehension of receptive skills? M Rashtchia, Z Zokaeeb, AR ghaffarinejadc, MM Sadeghic a Islamic Azad University North Branch, Foreign language and Literature Department, Tehran, Iran, bIslamic Azad University Science and Research Branch, Foreign language and literature Department, Tehran, Iran, cSchool of Medicine, Kerman University of Medical Sciences, Kerman, Iran

International Society for Bipolar Disorders 4601 Baum Blvd, 1st Floor, Room 171, Pittsburgh, PA 15213, USA Phone +1-412-802-6940 / Fax +1-412-802-6941 www.isbd.org

Congress Organizers: Kenes Turkey Sar Asma Sokak No. 9, 34464 Yeniky - Saryer, Istanbul Phone: +90 212 299 9984 / Fax: +90 212 299 9977 e-mail: isbd@kenes.com

www.isbd2012.org

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