CORTEZANO, GENEVA P. B.S.

PHARMACY 2
PHARMACOLOGIC CATEGORY/USE
Antidiabetic agent (Diabetes Mellitus) Alpha-Glucosidase Inhibitors, which means that it keeps the body from processing carbohydrates efficiently. Antigout Xanthine oxidase inhibitor; structural isomer of hypoxanthine

GENERIC NAME
ACARBOSE

BRAND NAME
Glucobay Precose Prandase

MANUFACTURER
Bayer HealthCare Bayer HealthCare Bayer HealthCare

INDICATION
Recommended for the treatment of non-insulin dependent (NIDDM) diabetes mellitus in patients inadequately controlled on diet alone, or on diet and oral hypoglycaemic agents.

DOSAGE FORM
Tablet (Oral) Tablet (Oral) Tablet (Oral)

PRE- & POSTPRANDIAL ADVICE

With meals. Take w/ first bite of a main meal

ADVERSE EFFECT
Flatulence Diarrhea Abdominal discomfort/pain

PREGNANCY CATEGORY
B

ALLOPURINOL

Zyloprim AlOprim Alpurin

GlaxoSmithKline Nabi EuroHealthCare

It is prescribed for patients who have primary or secondary gout, and for patients with elevated levels of serum and urinary acidic levels, such as those receiving cancer treatments for leukemia and lymphoma. It can also be used to treat people who have calcium disorders that result in high levels of daily uric acid.

Tablet (Oral) Powder for injection (IV Infusion) Tablet (Oral)

With meals. Take immediately after meals

Oral therapy: pruritic maculopapular rash. IV therapy: rash, renal failure/impairment, nausea, vomiting

AMIKACIN

Kormakin Cimmik Arbicin

One Pharma Karnataka Syncom

Anti-infective (systemic) Aminoglycoside Septicemia, bronchochiectasis, pneumonitis, pulmonary pus, CNS infections such as meningitis, bones & joints, skin & soft tissue infections, peritonitis, burns & post-op infections, serious, complicated & recurrent UTI.

Injection (Parenteral) Injection (Parenteral) Injection (Parenteral)

With meals. Take immediately after meals

Ototoxicity & nephrotoxicity Auditory, vestibular & renal toxicity & neuromuscular blockade Skin rash, fever, headache, paresthesia, tremor, nausea & vomiting; Eosinophilia, arthralgia, anemia & hypotension

AMITRIPTYLINE

Vanatrip Elavil Endep

GM Pharmaceuticals AstraZeneca Roche Laboraatories Tricyclic Antidepressant Treat symptoms of depression For the treatment of anxiety, bipolar disorders, and depression.

Tablet (Oral) Tablet (Oral) Tablet (Oral)

With or without meals

AMLODIPINE

Norvasc Amlodine

Pfizer InnoGen Pharma

Antihypertensive Calcium Antagonist HTN, angina, myocardial ischemia. Reduce the risk of coronary revascularization, fatal CHD, non-fatal MI & stroke

Tablet (Oral) Tablet (Oral) Tablet (Oral)

With or without meals

Amcal

OEP Phils

ATOVAQUONE

Mepron Malrone Malarone Pediatric

GlaxoSmithKline GlaxoSmithKline GlaxoSmithKline

Medication that interferes with the reproduction of protozoa (singlecell organisms) that can cause disease in the body. Prevent pneumonia caused by a fungal infection called Pneumocystitis carinii Antihypertensive Beta-blockers Treat angina

Suspension (Oral) For the treatment or prevention of Pneumocystis carinii pneumonia in patients who are intolerant to trimethoprim-sulfamethoxazole (TMP-SMX). Also indicated for the acute oral treatment of mild to moderate PCP in patients who are intolerant to TMP-SMX. Tablet (Oral) Tablet

With meals

ATENOLOL

Tenormin Velorin Tenor-Bloc

AstraZeneca Remedica Intas

Management of HTN, angina pectoris, cardiac arrhythmia & MI.

Tablet (Oral) Tablet (Oral) Tablet (Oral)

With or without meals. Take this medication with a full glass of water. Take at the same time everyday

nausea, vomiting, constipation, diarrhea, loss of appetite; dry mouth, unpleasant taste; feeling dizzy, drowsy, or tired; trouble concentrating; nightmares; blurred vision, headache, ringing in your ears; breast swelling (in men or women); or decreased sex drive, impotence, or difficulty having an orgasm Headache, edema, fatigue, somnolence, nausea, abdominal pain, flushing, palpitations, dizziness Asthenia, vasodilation & epitaxis mild nausea, vomiting, stomach pain or upset, diarrhea, constipation; headache; weakness, dizziness; muscle pain; mild skin rash; sweating; or sleep problems (insomnia). decreased sex drive, impotence, or difficulty having an orgasm; sleep problems (insomnia); tired feeling; or anxiety, nervousness.

AZTREONAM

Aztram

Shanxi C & Y Pharma

Antibacterial Monocyclic lactam antibiotic Monobactam Anti-infectives Treatment of infections caused by susceptible organisms such as bone & joint infections, gonorrhea, intra-abdominal & pelvic infections, lower respiratory tract infections, meningitis, septicemia, skin & soft tissue infections & UTI.

Powder for injection

BECLOMETHASO NE

Beclovent Vanceril Qvar

GlaxoSmithKline Pharma Pac Janssen Pharmaceuticals

Inhaled corticosteroid Anti-inflammatory Glucocorticoid

For the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older

Aerosol (Inhalation) Aerosol with adapter (Inhalation) Aerosol with adapter (Inhaler)

With or without meals

BEPRIDIL

Vascor 200mg Vascor 300mg Vascor 400mg

Janssen Pharmaceuticals

Antihypertensive Calcium Channel Blockers Treat angina Anti-arryhtmia Calmodiumantagonist

Tablet (Oral) For the treatment of chronic stable angina (classic effortassociated angina).

Maybe taken with meals or at bedtime. Take each dose with a full glass of water

BLEOMYCIN Bemocin Bloicin-S Blenoxane Fresenius Kabi Korea United Pharma Bristol-Myers Squibb Ctotoxic Chemotherapy cancer medication that interferes with the growth and spread of cancer cells in the body. Bleomycin is used to treat squamous cell carcinoma, a skin cancer that can affect the mouth, throat, nose and sinuses, penis, vagina, cervix, and other. Bleomycin is also used to treat Hodgkin's disease and non-Hodgkin's lymphoma, testicular cancer, and malignant pleural effusion (a build-up of fluid in the outer tissues of the lungs, caused by certain types of cancer). Powder for injection (Injectable) Powder for injection Powder for injection (Injectable) With meals

Skin rash, urticaria, eosinophilia; Diarrhea, nausea, vomiting & abnormal taste; Phlebitis or thrombophlebitis after IV administration; Pain or swelling after IM inj.; Pseudomembranous colitis, jaundice, hepatitis, increase in liver enzymes & prolongation of prothrombin & partial thromboplastin times. Headache Dryness in mouth, nose, or throat White patches or sores inside mouth or on lips Stuffy nose, sinus pain, sore throat, cough Horseness or deepened voice unusual fatigue or tiredness; nausea, upset stomach, diarrhea, or constipation; headache; nervousness or mild dizziness; insomnia; or tremor (shaking). Pneumonitis Erythema, rash, vesiculation, hyperpigmentation, tenderness of the skin, hyperkeratosis, nail changes, alopecia, pruritis & stomatitis Dry hacking cough, dyspnea, tachypnea, fever & cyanosis Hypotension,

Bleomycin treats only the symptoms of cancer but does not treat the cancer itself. BROMOCRIPTINE Parlodel 2.5mg Parlodel 5mg Novartis Pharmaceuticals Treat type 2 diabetes Treat Parkinsons Disease Treat dysfunctions associated with hyperprolactinemia For the treatment of galactorrhea due to hyperprolactinemia, prolactindependent menstrual disorders and infertility, prolactin-secreting adenomas, prolactin-dependent male hypogonadism, as adjunct therapy to surgery or radiotherapy for acromegaly or as monotherapy is special cases, as monotherapy in early Parksinsonian Syndrome or as an adjunct with levodopa in advanced cases with motor complications. Bromocriptine has also been used off-label to treat restless legs syndrome and neuroleptic malignant syndrome. For the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing. Capsule (Oral) Tablet (Oral) Capsule, Powder, tablet (Compoundi ng, Oral) With meals

mental confusion, fever, chills & wheezing dizziness, spinning sensation, mild drowsiness, feeling weak or tired; headache, depressed mood, sleep problems (insomnia); nausea, vomiting, stomach pain, loss of appetite, diarrhea, constipation; or cold feeling or numbness in your fingers. B

Bromocriptine Mesylate

LEK Pharmaceuticals

BROMPHENIRAMI NE

Brovex Vazol Siltane

BUPROPION

Budeprion Wellbutrin Zyban SR

Athlon Pharmaceuticals Inc. Wraser Pharmaceuticals Silarx Pharmaceuticals Inc. Teva Pharmaceuticals USA GlaxoSmithKline GlaxoSimthKline

Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria Unicyclic, aminoketone antidepressant

For the treatment of depression and as aid to smoking cessation.

Suspension (Oral) Solution (Oral) Solution (Oral) Tablet (Oral) Tablet (Oral) Tablet (Oral)

With or without meals

With or without meals

BUTOCONAZOL E

Femstat Mycelex-3 Gynazole-1

Syntex Laboratories Inc. Bayer HealthCare Ther-Rx Corporation

Antifungal

Treatment of complicated vulvovaginal candidiasis, including infections that are recurrent (4 episodes in 1 year), severe (extensive vulvar erythema, edema, excoriation, fissure formation), caused by Candida other than C. albicans, or occurring in women

Cream (Intravaginal) Cream (Intravaginal) Cream (Intavaginal)

With meals

Sleepiness, fatigue, or dizziness Headache Dry mouth Difficulty in breathinf or enlarged prostate headache or migraine; sleep problems (insomnia); nausea, vomiting, constipation, dry mouth; dizziness, tremors (shaking); appetite changes, weight loss or gain; mild itching or skin rash, increased sweating; or loss of interest in sex. Vulvar/vaginal burning, itching, soreness and swelling, pelvic or abdominal pain or cramping.

with underlying medical conditions (uncontrolled diabetes mellitus, HIV infection, immunosuppressive therapy, pregnancy). Complicated infections generally require more prolonged treatment than uncomplicated infections. CANDESARTAN Blopress 8mg Bloporess 16mg Candez 8mg Candez 16mg Blopress Plus Bactizon Sulperazone Cefobid Takeda LR Imperial Takeda PT Sanbe Farma Pfizer Pfizer Cephalosporin Treatment of susceptible infections especially those due to Pseudomonas sp including biliary tract infections, bone & joint infections, cystic fibrosis, endophthalmitis, infections in immune-compromised patients, upper respiratory tract infections, septicemia, skin infections & UTI. Angiotensin II Antagonist Antihypertensive Tablet (Oral) Management of HTN. Used in heart failure in patients with impaired left ventricular systolic function Tablet (Oral) Tablet (Oral) Powder for injection Powder for injection Powder for injection Should be taken on an empty stomach With or without meals Headache, upper respiratory tract infection, back & pain, dizziness, nausea Increase in serum uric acid, blood glucose & SGPT Allergic reactions, reversible neutropenia, +ve direct Coombs test, anemia & reduced hematocrit, transient eosonophilia & hypoprothrombinemi a. Transient elevation of SGOT, SGPT & alkaline phosphotase. Loose stools, diarrhea, phlebitis at the site of inj or transient pain on IM administration Gastrointestinal Disturbances, such as gastrointestinal discomfort Nausea Diarrhea C; D in 2nd & 3rd trimesters

CEFOPERAZONE

CELECOXIB

Celebrex 100mg Celebrex 200mg Celebrex 400mg Celexib Celcoxx

Pfizer

InnoGen Pharma Getz Pharma

CHLORHEXIDINE

Betasept Calgon Vesta Hibistat

Escalon Ophthalmics Inc Bristol-Myers Squibb AstraZeneca

NSAIDs treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis Disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque

Capsule (Oral) Treatment of RA & osteoarthritis. Adjunct in treatment of adenomatous colorectal polyps. Management of acute pain & dymenorrhea.

Capsule (Oral) Capsule (Oral)

With or without meals. Dose for OA/RA may be given with meals, but doses for FAP must be given with meals

C; D in 3rd trimester or near delivery

For reduction of pocket depth in patients with adult periodontitis, used as an adjunct to scaling and root planing procedures. Also for prevention of dental caries, oropharyngeal

Liquid, Soap (Topical) Solution,Soa p (Topical) Liquid

With meals

Mouth irritation Dry mouth Unusual or unpleasant taste in mouth Decreased taste

decontamination in critically ill patients, hand hygiene in health-care personnel, general skin cleanser, and catheter site preparation and care. COUMARIN Athrombin Jantoven Zyfarin Abbott Bristol-Myers Squibb Antithrombosis Treatment of renal vascular occlusion, atrial fibriliation and flutter.

(Topical)

sensation

White crystals, pink, green or orange

With meals

Diarrhea, nausea, vomiting, abdominal pain

COLCHICINE

Gountil 500mg Colchicine

Inga PD-RX Pharmaceuticals

Antigout Relief of acute gout. Prophylaxis of acute attacks, particularly during the 1st few mth of treatment with allourinol or uricosurics. Conditions including amyloidosis Behcets syndrome, familial, Medeterranean fever, idiopathic thrombocytopenic purpura, pericarditis, primary biliary cirrhosis & pyoderma gangocenosum Treatment of hyperlipoproteinemi a type III and severe hypertriglyceridemi a

Tablet (Oral) Powder, Liquid, Tablet (Compoundi ng, Intravenous, Oral)

With meals

CLOFIBRATE

Atromid-S

Wyerth-Ayerst Laboratories

Capsule (Oral) For Primary Dysbetalipoproteinemia (Type III hyperlipidemia) that does not respond adequately to diet. This helps control high cholesterol and high triglyceride levels.

Take eacd dose with a full glass of water

Diarrhea, nausea, vomiting, abdominal pain Bone marrow depression with agranulocytosis, thrombocytopenia, aplastic anemia, peripheral neuropathy, myopathy, rashes & alopecia have occurred on prolonged treatment. bloating or flatulence; nausea, vomiting, or diarrhea; headache; dizziness or drowsiness; or impotence.

CLOPIDOGREL

Plavix 75mg Plavix 300mg Trombix Winthrop Clopidogrel

Sanofi-aventis Standard Chem Winthrop

Antithrombotic

For the reduction of atherosclerotic events in peripheral arterial disease or within 35 days of MI or within 6 months of ischemic stroke. For the treatment of patients suffering from non-ST segment elevation acute coronary syndrome, including patients undergoing a stent placement following in combination with ASA in medically-treated patients eligible for thrombolytic therapy

Tablet (Oral) Tablet (Oral) Tablet (Oral)

With or without meals

GI hemorrhage, diarrhea, abdominal pain, dyspnea Haematoma Epistaxis Bruising Bleeding at puncture site

DANTROLENE

Dantrium Dantrium Intravenous Dantrolen Sodium

Procter and Gamble Pharmaceuticals Procter and Gamble Pharmaceuticals Global Pharmaceutical Corporation

Muscle relaxant

Treat muscle spasticity (stiffness and spasms) caused by conditions such as a spinal cord injury, stroke, cerebral palsy, or multiple sclerosis. Prevent muscle stiffness and spasms caused by malignant hyperthermia (a rapid rise in body temperature) that can occur during surgery with certain types of anesthesia.

Capsule (Oral) Powder for injection (Intravenous) Capsule (Oral)

Take this medicine with a full glass of water

DICYCLOVERINE

Relestal

Pediatrica

Antispasmodics

Spasdon Bentyl

AD-Drugstel

Childrens colic, functional gut disturbances, renal & biliary colic

Syrup (Oral) Oral drops (Oral) Oral drops (Oral)

With or without meals. May be taken before or after meals

DOMPERIDONE

Motilium 10mg Moitilium 1mg/ml Dompenyl Gasidone

Janssen

Antiflatulence Symptomatic relief of acute nausea & vomiting. Treatment of nausea & vomiting caused by levodopa or bromocriptine administration in Parkinsons disease

Korea United Pharma Stallion Labs

Tablet (Oral) Oral drops (Oral) Tablet (Oral) Tablet (Oral)

With or without meals.

DIPIVEFRIN

Alcon Propine AKPro

Watson Pharmaceuticals Allergan Inc. Akorn

Ophthalmic

Indicated as therapy for the control of intraocular pressure in chronic open-angle glaucoma and ocular hypertensive patients. Patients responding inadequately to other antiglaucoma therapy may respond to replacement with or addition of Dipivefrin HCl 0.1%, Alcon.

Solution (Ophthalmic) Solution (Ophthalmic) Solution (Ophthalmic)

With or without meals

drowsiness, dizziness, weakness, tired feeling; mild diarrhea or constipation; mild nausea, vomiting, stomach pain; problems with speech, balance, or walking; headache, confusion, vision problems; sleep problems (insomnia); sweating, drooling; or urinating more than usual. Increased IOP, cycloplegia, mydriasis, dry mouth, blurred vision, flushing, urinary hesitancy & retention, tachycardia, palpitations, constipation, elevated temperature, CNS excitation, rash, vomiting, photophobia Shock Gynecomostia, galctorrhea, hysterrhea Anorexia, cathatrsis, constipation, celialgia, dipsia, vomiting Extrapyramidal, circulatory & dermatologic effects. Burning. Stinging, or itching of eyes Blurred vision Redness of the eye or eyelid Sensitivity to light Eye pain headache

DIFLUNISAL

Dolobid Difludol Adomal

Merck & Company Inc. PubChem PubChem

NSAIDs Anti-inflammatory Cylcooxygenase inhibitors

For acute or long-term use for symptomatic treatment of the following: 1. Mild to moderate pain 2. Osteoarthritis 3. Rheumatoid arthritis

Tablet (Oral) Tablet (Oral) Tablet (Oral)

With meals

DESIPRAMINE

Norpramin Pentofran Sertofran

Aventis Pharmaceuticals PubChem PubChem

Tricyclic depressant NorepinephrineReuptake inhibitors Treatment of Depression

Tablet (Oral) Tablet (Oral) Tablet (Oral)

With or without meals

DONEPEZIL

Donezel Aricept Done-5

Micro Labs Eisai, HI Eisia

Neurodegenerative Disease Drug Symptomatic treatment of mild to moderately severe dementia in Alzheimers disease

Tablet (Oral) Tablet (Oral) InnoGen Pharma

With or without meals. Take before bedtime

mild nausea, stomach pain, vomiting, upset stomach; diarrhea, constipation, gas; dizziness, drowsiness, headache, tired feeling; sleep problems (insomnia); or ringing in your ears. vomiting, constipation; dry mouth, unpleasant taste; weakness, lack of coordination; feeling anxious, restless, dizzy, or drowsy; sleep problems (insomnia), nightmares; blurred vision, trouble concentrating, headache, ringing in your ears; breast swelling (in men or women); or decreased sex drive, impotence, or difficulty having an orgasm. Nausea, diarrhea, vomiting, insomnia, fatigue, dizziness, muscle gramps, anorexia, headache, general pain, syncope, ecchymosis, decreased weight, arthritis, depression, abnormal dreams, somnolence, frequent urination