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CONTENTS
SECTION 1Physical pharmacy
1. 2. 3. 4. 5. 6. 7.
States of Matter Micromeretics and Powder Rheology Surface and Interfacial Phenomenon Viscosity and Rheology Dispersion Systems Complexation Kinetics and Drug Stability
SECTION 4 Pharmaceutical
Biotechnology 1. 2. 3. 4. 5. 6. 7. 8. 9. 10.
Microbiology &Biotechnology
Importance of microbiology in pharmacy Structure of bacterial cell; Classification of microbes and their taxonomy Identification of Microbes Control of microbes by physical and chemical methods Sterilization Immunology and Immunological Preparations Genetic Recombination Antibiotics Microbial Transformations Enzyme Immobilization
1. Pre-formulation studies 2. Stabilization and stability testing 3. ICH Guidelines for stability testing of formulations 4. Performance evaluation methods 5. Bioavailability studies and bioavailability testing 6. GMP and quality assurance, Quality audit 7. Novel Drug delivery System
1. 2. 3. 4. 5.
Importance of fundamentals of organic chemistry in pharmaceutical sciences Structure and Properties Stereochemistry Stereoselective and stereospecific reactions Structure, Nomenclature, Preparation and Reactions of
6. 7. 8. 9. 10.
SECTION 10
1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13.
Biochemistry
Chemistry of lipids, Carbohydrates and Proteins Biochemistry in pharmaceutical sciences; The concept of free energy Enzymes Co-enzymes The Citric Acid Cycle Lipids Metabolism Biological Oxidation Metabolism of ammonia and nitrogen containing monomers Purine biosynthesis Pyrimidine biosynthesis Biosynthesis of Nucleic Acids Mutation Genetic Code and Protein Synthesis
Chromatography
13. 14. 15. 16. 17. 18. 19. Basic Chromatography TLC HPLC GLC HPTLC Paper Chromatography Column Chromatography
1. 2. 3. 4. 5. 6. 7. 8. 9.
Importance of basic fundamentals of physical chemistry in pharmacy Behaviour of Gases The Liquid State Solutions Thermodynamics Thermochemical equations; Phase rule; Adsorption Photochemistry Chemical Kinetics Quantum Mechanics
SECTION 14Pharmacology
1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. Fundamentals of general pharmacology Pharmacology of Peripheral Nervous System Pharmacology of Central Nervous System Pharmacology of Cardiovascular System Drugs Acting on the Hemopoietic System Drugs acting on urinary system Autacoids Drugs Acting on the Respiratory System Drugs acting on the Gastrointestinal Tract Pharmacology of Endocrine System Chemotherapy Principles of Toxicology Basic Concepts of Pharmacotherapy Therapeutic Drug Monitoring Concept of Essential Drugs and Rational Drug use
SECTION 15Pathophysiology
1. Cell Injury and Adaptations 2. Inflammation 3. Immunopathophysiology a. T and B cells, MHC proteins, antigen presenting cells, immune tolerance, pathogenesis of hypersensitivity reactions, autoimmune diseases, AIDS, Amyloidosis 4. Pathophysiology of Common Diseases: a. Depression, Asthma, Peptic ulcer, Ulcerative colitis, Hepatitis, Cirrhosis, Diabetes mellitus and Thyroid disorders, Tuberculosis, Urinary tract infections, Enteric infections, Upper respiratory infections, Anemias, Rheumatic diseases, Gout and Hyperuricemia, Acute Leukaemias, Hodgkin's disease. b. Asthma, diabetes, rheumatoid arthritis, gout, ulcerative colitis, neoplasia, psychosis, depression, mania, epilepsy, acute and chronic renal failure, hypertension, angina, congestive heart failure, atherosclerosis, myocardial
SECTION 16Pharmacognosy
1. Sources of Drugs 2. Classification of Drugs 3. Study of medicinally important plants belonging to the families with special reference to: a. Apocynacae, Solanaceae, Rutacease, Umbelliferae, Leguminosae, Rubiaceae, Liliaceae, Graminae, Labiatae, Cruciferae, Papaveraceae; 4. Cultivation, Collection, Processing and Storage of Crude Drugs a. Factors influencing cultivation of medicinal plants, Types of soils and fertilizers of common use. Pest management and natural pest control agents, Plant hormones and their applications, Polyploidy, mutation and hybridization with reference to medicinal plants. 5. Quality Control of Crude Drugs 6. CARBOHYDRATES and derived products a. agar, guar gum acacia, Honey, Isabagol, pectin, Starch, sterculia and Tragacanth; 7. Lipids a. Bees wax, Castor oil, Cocoa butter, Codliver oil, Hydnocarpus oil, Kokum butter, Lard, Linseed oil, Rice, Bran oil, Shark liver oil and Wool fat; 8. RESINS a. Study of Drugs Containing Resins and Resin Combinations like Colophony, podophyllum, jalap, cannabis, capsicum, myrrh, asafoetida, balsam of Tolu, balsam of Peru, benzoin, turmeric, ginger; 9. TANNINS a. Study of tannins and tannin containing drugs like Gambier, black catechu, gall and myrobalan; 10. VOLATILE OILS a. General methods of obtaining volatile oils from plants, Study of volatile oils of Mentha, Coriander, Cinnamon, Cassia, Lemon peel, Orange peel, Lemon grass, Citronella, Caraway, Dill, Spearmint, Clove, Fennel, Nutmeg, Eucalyptus,
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