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New Study: Direct evidence that exposure to electromagnetic fields elicits a stress response in the rat brain

Yang XS, He GL, Hao YT, Xiao Y, Chen CH, Zhang GB, Yu ZP. (2012). Exposure to 2.45GHz electromagnetic fields elicits an HSP-related stress response in rat hippocampus. Brain Res Bull. 2012 Apr 9. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed?term=22513040
This study was designed to determine whether electromagnetic field exposure could act as an environmental stimulus capable of producing stress responses. It assesses the changes in its stress-related gene and protein expression in the hippocampus after EMF exposure. Adult male Sprague-Dawley rats with body restrained were exposed to a 2.45GHz EMF at a specific absorption rate (SAR) of 6W/kg or sham conditions. cDNA microarray was performed to examine the changes of gene expression involved in the biological effects of electromagnetic radiation. Of 2048 candidate genes, 23 upregulated and 18 downregulated genes were identified. Of these differential expression genes, two heat shock proteins (HSP), HSP27 and HSP70, are notable because expression levels of both proteins are increased in the rat hippocampus.

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