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  • Thesun 2009-01-05 Page14 Gene Link To Rare Cause of Baldness

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    Flaws in a gene called U2HR are to blame for a condition called Maria Unna hereditary hypotrichosis, or MUHH. Children with MUHH have sparse or no hair at birth, followed by wiry or coarse hair in childhood but progressively lose it at puberty. Researchers found mutations of U2HR led to increased levels of HR, the death of hair follicles and thus greater likelihood of this kind of baldness.

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    Flaws in a gene called U2HR are to blame for a condition called Maria Unna hereditary hypotrichosis, or MUHH. Children with MUHH have sparse or no hair at birth, followed by wiry or coarse hair in childhood but progressively lose it at puberty. Researchers found mutations of U2HR led to increased levels of HR, the death of hair follicles and thus greater likelihood of this kind of baldness.

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    Thesun 2009-01-05 Page14 Gene Link To Rare Cause of Baldness

    Загружено:

    Impulsive collector
    Flaws in a gene called U2HR are to blame for a condition called Maria Unna hereditary hypotrichosis, or MUHH. Children with MUHH have sparse or no hair at birth, followed by wiry or coarse hair in childhood but progressively lose it at puberty. Researchers found mutations of U2HR led to increased levels of HR, the death of hair follicles and thus greater likelihood of this kind of baldness.

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    14 theSun | MONDAY JANUARY 5 2009

    news without borders

    S. Lanka
    separatist
    conflict
    far from
    over, say
    Gene link to rare cause of baldness
    PARIS: Scientists say they have pinned
    down a DNA mechanism that gives rise
    Children with MUHH have sparse
    or no hair at birth, followed by wiry or
    kind of mini-protein – that in turn affects
    a previously-identified protein called the
    follicles and thus greater likelihood of this
    kind of baldness.
    analysts to a rare but distressing form of baldness coarse hair in childhood but progressively human hairless monolog, or HR, which The study, published online yesterday
    pg 16 that strikes before adulthood. lose it at puberty. is crucial for the regeneration of hair in the journal Nature Genetics, offers
    Flaws in a gene called U2HR are to Researchers led by Xue Zhang of the follicles. a potential target for drugs that would
    blame for a condition called Maria Unna Peking Union Medical College in Beijing Sifting through the genome of 19 Chi- block this pathway, offering the hope that
    hereditary hypotrichosis, or MUHH, found that U2HR, located on Chromosome nese families with a history of MUHH, youngsters who inherit the mutations will
    named after the German trichologist who 8, acts as a key switch in the process. the team found mutations of U2HR led to one day keep their hair, say the authors.
    identified the problem. U2HR controls a small peptide – a increased levels of HR, the death of hair – AFP

    Pet dogs pay price as


    recession hits Hongkong
    HONGKONG: The recession isn’t just affecting process was ongoing could cost up to HK$35,000
    people in Hongkong: it’s also having an impact on (RM16,200), she said.
    animals as dogs are left behind by departing expa- “It’s a lot of money, especially for a family that
    triates, a relocation company said yesterday. no longer has an income coming in and doesn’t
    Jenny Wong, manager of ReloPet, said her know if it will have any income when it gets back
    company had seen a 400% increase in business home,” she said.
    in the past 12 months as more expatriates are laid Stacy Tucker, who runs Hongkong’s Ferndale
    off and said many dogs were being left behind. Kennels and Cattery, said she had seen a steady
    “We have seen a massive increase in people increase in people seeking to take their pets out
    and pets moving out of Hongkong because of this of Hongkong with them because of the credit
    financial tsunami,” she said. crunch.
    Wong said the number of people of leaving “It’s people who haven’t considered they will
    had risen sharply since October. “In December be leaving who are getting caught out and there
    alone we had 40 new jobs. A year before, we were are quite a lot of them, especially in the banking
    getting fewer than 10 bookings a month. sector.”
    “They are being uprooted the next day and with Sally Andersen who runs Hongkong Dog Res-
    pets, it’s really difficult especially when they’re cue said her shelter was “totally inundated” with
    going to Australia or the UK. Some countries need people seeking homes for unwanted pets. “I’m
    six months advance preparation.” getting so many calls now it’s difficult. I get about
    Taking a large dog back to a country like Aus- 10 calls a day,” she said. “We are already well over
    tralia and paying for its boarding fees while the our limit. – dpa

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