GABA and glycine supplements should both have a calming effect, helping to reduce anxiety and make you sleep better. But some people have asked me, what if they do the opposite? What if they cause anxiety and wake you up at night? Tune in for my answer. This episode is brought to you by Ancestral Supplements' "Living" Collagen. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-to-tail product line of grass-fed liver, organs, "living" collagen, bone marrow and more... in the convenience of a capsule. For more information or to buy any of their products, go to https://chrismasterjohnphd.com/ancestral This episode is brought to you by Ample. Ample is a meal-in-a-bottle that takes a total of two minutes to prepare, consume, and clean up. It provides the right balance of nutrients needed for a single meal, all from a blend of natural ingredients. Ample is available in original, vegan, and keto versions, portioned as either 400 or 600 calories per meal. I'm an advisor to Ample, and I use it to save time when I'm working on major projects on a tight schedule. Head to https://amplemeal.com and enter the promo code “CHRIS15” at checkout for a 15% discount off your first order.” To get these episodes free of ads, with transcripts, and weeks or sometimes even months before they are released to the public, along with access to monthly live Q&A sessions, sign up for the CMJ Masterpass at https://chrismasterjohnphd.com/masterpass. Use the code LITE10 to get 10% off. To make it easier to get the discount, use this link, which has the coupon already activated: https://masterpass.chrismasterjohnphd.com/cmj-masterpass/2200/buy?coupon=LITE10 Here are links to things mentioned in the episode: Testing Nutritional Status, The Ultimate Cheat Sheet is at https://chrismasterjohnphd.com/cheatsheet (use the code LITE5 to get $5 off) The specific comment addressed in this episode: https://chrismasterjohnphd.com/2018/10/11/dont-use-niacin-buffer-excess-methyl-groups/#comment-47351 For *many* resources on glycine: https://chrismasterjohnphd.com/methylation On GABA, 5 Ways to Help With Glutamate Sensitivity and Glutamate Dominance: https://chrismasterjohnphd.com/2018/06/14/5-ways-help-glutamate-sensitivity-glutamate-dominance/ 3 Ways to Get Enough Potassium: https://chrismasterjohnphd.com/2018/07/19/3-ways-get-enough-potassium/ The Best Way to Supplement With Potassium: https://chrismasterjohnphd.com/2018/08/14/best-way-supplement-potassium/ How to Manage Your Magnesium Status: https://chrismasterjohnphd.com/2018/08/23/manage-magnesium-status/ How to Manage Your Thiamin (Vitamin B1) Status: https://chrismasterjohnphd.com/2018/08/28/monitor-thiamin-vitamin-b1-status/ How to Manage Your Vitamin B6 Status: https://chrismasterjohnphd.com/2018/11/13/manage-vitamin-b6-status/   Why You Should Be Careful With Niacin and Nicotinamide Riboside: https://chrismasterjohnphd.com/2018/07/26/careful-niacin-nicotinamide-riboside/ DON’T Use Niacin to Buffer Excess Methyl Groups: https://chrismasterjohnphd.com/2018/10/11/dont-use-niacin-buffer-excess-methyl-groups/