The TWiMmers discuss culture-independent discovery of malacidin antibiotics, and unfolding of relaxase during bacterial conjugation. Hosts:  Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Malacidins from soils (Nat Micro) Excellent antibiotic resistance threat report (CDC, pdf) Jo Handelsman on Women’s History Month (CBS) Unfolding relaxase during bacterial conjugation (J Bact) Letters read on TWiM 172 Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv