Академический Документы
Профессиональный Документы
Культура Документы
Rao MD
Dr.T.V.Rao MD
Antimicrobial Resistance
-lactams B-lactamases, Macrolides Aminoglycosides Fluoroquinolones Tetracycline's Chloramphenicol Sulfonamides Trimethoprim Vancomycin Streptogramins
altered PBP, efflux MLS, efflux AME, permeability altered topoisomerases, efflux efflux, altered target CAT, efflux altered dihydropteroate synthase altered dihydrofolate reductase bypass pathway
MLS, efflux, enzyme modification altered target
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Rifampicin
Genetic diversity
nucleotide substitution, DNA rearrangements and gene acquisition Gene acquisition transformation, transduction and conjugation
antibiotic use
to treat or prevent infections mixed into feed to promote growth of agricultural animals
Some drugs excreted in metabolized amounts via the urine and feces Some yield bioactive metabolites. Some excreted as conjugates
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Metabolism of Antibiotics
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Basic research: physical and biological sciences including chemistry, pharmacology, toxicology, genetics, etc
Research on Research on social and behavioural factors factors influencing health affecting and their relation to functioning of equity, access, programs, Research on lifestyle and healtheffectiveness of health systems management, seeking behaviours, targeting, functions, efficiency, etc impact on effectiveness, system factors behavior, affecting access disease scale-up, monitoring and burdens and evaluation, etc public health, etc
Understanding the biological nature of diseases; creating products to prevent or treat disease states
Understanding how to test, scale-up and follow through the introduction of interventions and optimize their benefits
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Ongoing effort by a health care institution to optimize antimicrobial use among hospitalized patients to ...
- Improve patient outcomes - Ensure cost-effective therapy, and - Reduce adverse sequelae of antimicrobial use (including antimicrobial resistance).
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Keep aware National/Provin cial Surveillance Programs Get to know your microbiology laboratory
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Infection Control in the office & hospital Decrease antibiotic prescriptions for viral URIs by half! Improve communication with patients
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Proper hand washing is the most effective way to prevent the spread of infections in hospitals. If you are a patient, don't be afraid to remind friends, family and health care providers to wash their hands before getting close to you.
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Preventive Measures .
Covering coughs and sneezes Staying up-todate with immunizations Using gloves, masks and protective clothing Making tissues and hand cleaners available Following hospital guidelines when dealing with blood or contaminated items
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Microbiologists
should bring in change with dedication to bench work, and Proficiency Testing to improve the quality to services in Health care
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Be able to list the recommended components of an antibiotic stewardship program B. Be able to detect antibiotic use improvement opportunities from the analysis of utilization data C. Be able to explain the barriers for successful implementation of such a program
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WORKSTREAMS
1. INFORMATION MANAGEMENT (HPS AND ISD) 2. EDUCATION (NES) 3.ORGANISATION AND ACCOUNTABILITY (NQIS)
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WORKSTREAMS
4.INFECTION MANAGEMENT (SPA,NQIS,NES,HPS-ISD, Professional Organisations)
All the work-streams work in parallel but with vertical integration Work stream work underpinned by an AMT Clinical Network
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EVIDENCE OF BENEFIT FOR INTERVENTION ALSO TARGET SYSTEMS CHANGE TO BRING ABOUT DESIRED BENEFIT INTEGRATE, DEVELOP AND IMPLEMENT EXISITING AND NEW PROJECTS OVER 3 YEAR TIME FRAME: WORK CLOSELY WITH WORK PROGRAMMES OF KEY STAKEHOLDERS (e.g HPS, SPA) IMMEDIATE OPPORTUNITIES AROUND SNAP-CAP, C.difficle and Surgical Prophylaxis.
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Goals of Committee
Assist providers in appropriate use of antimicrobial therapy with improved patient outcomes Slow the development of antimicrobial resistance Develop evidence- based appropriate use guidelines Educate providers and staff regarding guidelines Track resistance patterns and report back to medical and hospital staff Report committee progress and outcomes to P&T, and Executive Committees
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Programme Created by Dr.T.V.Rao MD for Awareness on Use and Misuse of Antibiotics by Medical Professionals
Email
doctortvrao@gmail.com
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