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Bone 3-5 years

Skin 3-5 days

Vessels 7-10 days

Neurons ?





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M. Ratajczak (USA) Very Small Embrionic Like Stem Cells (VSELs): our key to
longevity and passkey to cancer?

Decellularised organs for tissue engineering


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50

Time after placental cells transplantation, days

Acta Physiologica Sinica, February 25, 2010, 62 (1): 79-85

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Turritopsis nutricula
(Sebastes aleutianus) 205
100

(Megalochelys gigantea) 255
Arctica islandica 405

http://www.iangoddard.com/cr.htm

Survival curves for CBA/Ca parabiotic mice


after disconnection.

Determination of life expectancy


Single
mice

Parabiosis,
3 months

Disconnection

Number of surviving animals, %


100
80
60
40
20
0
0

10

15
Months

20

25

30

Y-Iso
Y-Hetero
O-Hetero
O-Iso

Parabiosis Scheme
Exchange by:
Serum factors,
hormones,

lymphoid cells,
stem cells,
1 Young isochronic pairs (Young-Iso)
2 Young heterochronic pairs (Young-Hetero)
3 Old heterochronic pairs (Old-Hetero)
4 Old isochronic pairs (Old-Iso)

The rate of blood


exchange:

16 L/h or

Young

Old

0.66% blood volume


per hour
(Gibney B. et al 2011).

3 -
D8+CD44+

3 -

6
D8+CD44+ ;
CD4/CD8

10
D8+CD44+ ;
CD4/CD8 ;

CD4+CD44+ ,

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Mean
MeanSE
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2012 :
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