Penile Cancer

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Trio Wicaksono / 0718011088 Florencya Adys / 0718011058 Idhar Trisna Damayanti / 0818011066

Oleh:

Perceptor:
Dr. Mars Dwi Tjahjo, Sp. U

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Anatomy

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P e n i l e c a n c e r i s u n c

Overview

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P h i m o s i s i s p r e

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P h i m o s i s H P V I n f

Etiology

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P e n i l e c a n c e r s

Pathophysiology

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T h e g r o w t h r a t e s o f

Pathophysiology

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Clinical Manifestation

Penile tumors can originate anywhere on the penis, but most are found on the glans (48%) and prepuce (21%). Typical presentations of penile cancer include a lesion that has failed to heal, a subtle induration in the skin, a small excrescence, a papule, a pustule, a warty growth, a large exophytic growth, or a reddened area on the glans The manisfestation can be a hyperemic area on the glans or near the urethral meatus. They can be exophytic or flat, or an ulcerated lesion may be present. A sensation of itching or burning under the foreskin or an ulceration of the glans are the most common presenting symptoms. Pain is rarely present.
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P e n i l e l e s i o n s c a

Presentation

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Staging
The Jackson classification is as follows: Stage I (A): The tumor is confined to the glans, prepuce, or both. Stage II (B): The tumor extends onto the shaft of the penis. Stage III (C): The tumor has inguinal metastasis that is operable. Stage IV (D): The tumor involves adjacent structures and is associated with inoperable inguinal metastasis or distant metastasis
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The TNM classification of the primary tumor (T) is below. These stages simply relate the presence or absence of nodal and distant metastases.

TX: Primary tumor cannot be assessed. T0: Primary tumor is not evident. Tis: CIS is present. Ta: Noninvasive verrucous carcinoma is present. T1: Tumor invades subepithelial connective tissue. T2: Tumor invades corpora spongiosum or cavernosum. T3: Tumor invades the urethra or prostate. T4: Tumor invades other adjacent structures.
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T h e

W H O

h i s t o p

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N o s p e c i f i c l a b o r a t o

Laboratory Studies

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M R I a n d u l t r a s o n o g r a

Imaging Studies

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P a t i e n t s w h o a r e d i a

Treatment

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T h e p r i m a r y g o a l

Medical Therapy

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R a d i a t i o n t h e r a

Radiation Therapy

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C a n d i d a t e s f o r r a d i a

Radiation Therapy

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A w i d e v a r i e t y

Chemotherapy

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T h e s t a n d a r d o f t

Surgical Therapy

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Prognosis

The prognosis of penile cancer is primarily related to the presence or absence of inguinal node metastasis. Untreated patients with inguinal metastases rarely survive 2 years. Of those with clinically palpable adenopathy and histologically proven metastases, 20-50% are alive at 5 years following inguinal lymphadenectomy An 82-88% 5-year survival rate has been reported when only 1-3 lymph nodes are involved. Patients with 1-2 involved inguinal nodes that do not contain poorly differentiated cancer have a 90% 5-year survival rate. When the nodes are positive, the overall recurrence rate is 80%, and the 5-year survival rate is 10%-15% Powerpoint Templates

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