Skin as an organizing model

What is it? (Anatomy) What does it do? (Physiology) What is it made of? (Histology) Where does it come from? (Embryology)

Frolich, Human Anatomy, Skin

What is it (anatomy)?
Outer covering of body Keratinized
Hairhead, pubic regions Nailsfingers, toes

Divided into segments called dermatomes (Zebra-man)

CE (clinical example): Shingles

Frolich, Human Anatomy, Skin

What does it do (physiology)?

[brainstorm]

Frolich, Human Anatomy, Skin

What does it do?

PROTECTION
Air = desiccation Water = bloating/pruning Sun/u-v = burns Cold/heat = frostbite/heat stroke/thermoregulation

STRUCTURAL
Integrity of body Muscle attachment
Frolich, Human Anatomy, Skin

How does it do it?

PROTECTION (mostly epidermis)
Desiccationkeratin, lipid layer Water = keratin, lipid layer Sun/u-v = role of pigment/melanin Cold/heat = surface blood vessels

STRUCTURAL (mostly ddermis)

IntegrityDermal layer has network of tough collagen fibers in connective tissue Sub-dermal layer where muscle tendons insert
Frolich, Human Anatomy, Skin

What is it made of?

(histologystudy of tissues) Layers of skin are two fundamental types of tissue organization
Epidermis = epithelium Dermis = connective tissue

Frolich, Human Anatomy, Skin

Frolich, Human Anatomy, Skin

Epidermisa stratified epithelium

Frolich, Human Anatomy, Skin

Dermisconnective tissue substrate

Frolich, Human Anatomy, Skin

Skin is really an organ

Made up of two very different basic tissue types
the epidermis which is composed of epithelial tissues The dermis which is composed of connective tissue

On to a review of basic tissue types

Frolich, Human Anatomy, Skin

(Tissues presentation)

Where does it come from (Embryology)

After review of basic tissue types, on to introduction to embryology and basic human body plan
outer and inner tubes of body (skin as epithelial layer and part of skeletal structure of outer tube) Segmentation (skin reflects basic segmented organization of human body seen in vertebrae, ribs, nerves, etc.)
(Basic Human Body Plan presentation)
Frolich, Human Anatomy, Skin