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PROBLEMS FACED BY MULTICELULAR ORGANISMS IN OBTAINING THEIR CELLULAR REQUIREMENTS AND REMOVING THEIR WASTE PRODUCTS
SIZE
TSA (CM)
SMALL
MEDIUM LARGE
2X2X2 4X4X4
24 96
8 64
3.0 1.5
The
size of the cubes represents the size of organisms As a cube increases in size, its TSA/V ratio decreases. The larger the organism, the smaller its TSA/V ratio.
The paramecium has a TSA/V ratio of about 400 whereas man has a TSA/V ratio of about 0.3 In small organisms, the TSA/V ratio is large enough for diffusion of materials to all parts of the body
In large organisms, the TSA/V ratio is too small for materials to reach all parts of the body This problem is overcome by having a transport / circulatory system
2 m
- which provides large surface area
to diffuse oxygen
Haemoglobin combines with oxygen to form oxyhaemoglobin (HbO8) A small amount of co2 can also bind with haemoglobin to form carbaminohaemoglobin
disease cells:
Granulocytes
Have granular cytoplasm and lobed nuclei 3 types of granulocyte: 1) Neutrophils (62%) - phagocytes 2) Eosinophils (2%) - help to control allergic response - nucleus with 2 lobes 3) Basophils (0.5%) - secrete heparin to prevent from blood clotting - nucleus with two lobes or S-shaped
Agranulocytes
Smooth rounded nucleus with no granules 2 types of agranulocytes: 1) Monocytes: - largest leucocytes - large bean-shaped nucleus 2) Lymphocytes: - smallest leucocytes - some produce antibodies whereas others destroy infected cells
PLATELETS
Small irregularly shaped cell fragments formed in the bone marrow 250 000 in 1 cubic ml of blood lifespan of 5-9 days before destroyed in the spleen and liver play important role in blood clotting
PLASMA
yellowish fluid in blood 90% of plasma is water and 10% dissolved solutes (digested nutrients, dissolved gases, minerals, hormones)
2) Transport of carbon dioxide CO2 released from cellular respiration will diffuse into surrounding capillaries 70% of CO2 will combine with water
Carbonic anhydrase
CO2 + H2O H2CO3 (carbonic acid) H+ + HCO3- (hydrogen carbonate ion) About 23% combines with amino group and is transported as carbaminohaemoglobin 7% dissolves directly into blood plasma
3) Transport of absorbed food materials all digested food materials from villi in small intestine such as simple sugars, amino acids and water-soluble vitamins are transported by the hepatic portal vein ---- > liver ----- > heart for general circulation Fatty acids, glycerol & vit A, D, E and K from lacteals are transported by the lymph ----- > blood circulatory system via the left subclavian vein
4) TRANSPORT OF WASTE PRODUCT Deamination: Excess amino acids in liver is converted to urea. Urea is transported by blood to kidneys to be excreted 5) TRANSPORT OF HEAT 6) TRANSPORT OF HORMONES 7) TRANSPORT OF WATER TO TISSUES (TEXT BOOK PAGE 9)
FUNCTION OF HAEMOLYMPH
Blood-like fluid that flows in certain invertebrates with open circulatory system Tubular heart pumps the haemolymph into fluid-filled spaces called haemocoel
FUNCTION OF HAEMOLYMPH
Nutrients from digested food and hormones diffuse from haemolymph into cells. Waste product diffuse out from cells to surrounding haemolymph
arterioles
Branch out
capillaries
venules
join join
veins
Arteries are blood vessels that carry away blood from heart Capillaries are the sites for the exchange of respiratory gases, nutrients, and wastes. Veins transport blood back to the heart