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increased osteoclastic
activity
thinning of the trabecular bone
wide zones of osteoid rimmed
with activated osteoblasts
CONNECTIVE TISSUE
COLUMNAR CELLS WITH
REVERSE POLARISATION
SATELLITE CYSTS
EPITHELIAL RESTS
CORRUGATION OF SURFACE
EPITHELIUM
SEPERATION OF EPITHELUM
FROM CONNECTIVE TISSUE
Odontogenic keratocyst. The epithelial lining is 6 to 8
cells thick (arrow), with a hyperchromatic and palisaded
basal cell layer. Note the corrugated parakeratotic surface.
• Odontogenic keratocyst. The characteristic
microscopic features have been lost in the central
area of this portion of the cystic lining because of the
heavy chronic inflammatory cell infiltrate. ( arrow)
Odontogenic Keratocyst
(‘primordial cyst’, ‘benign cystic tumor’)
Screening for Gorlin-Goltz syndrome:
multiple jaw cyst,
bifid rib, multiple naevi and
basal cell carcinomas of the skin
CYSTIC LUMEN
CONNECTIVE TISSUE
BLOOD CAPILLARY
FIBROBLAST
Dentigerous cyst. This inflamed dentigerous cyst shows a
thicker epithelial lining with hyperplastic rete ridges. (Arrow )
The fibrous cyst capsule shows a diffuse chronic
inflammatory infiltrate.
Dentigerous cyst. This noninflamed dentigerous cyst
shows a thin, nonkeratinized epithelial lining.
( arrow)
Dentigerous cyst. Scattered mucous cells can be
seen within the epithelial lining. ( Arrow)
CALCIFYING ODONTOGENIC
CYST
CONNECTIVE TISSUE
FIBROBLAST
GHOST CELLS
CYSTIC LUMEN
BLOOD CAPILLARY
• ‘cracked-mud’,
‘corrugated’
Nodular (‘speckled
Hyperkeratosis Acanthosis
NBCCS
SATELLITE CYSTS
Cholesterol clefts