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Senger, 2003.
Transition Period
• Period of cessation of seasonal anestrus leading to the
breeding season
• Presence of multiple small non-ovulatory follicles
• Applications only speed up period; not eliminate
– Lighting
– GnRH
– Progestins
– Progestins + Estrogen
– eFSH
Transition Period
[Follice Size]
[# Follicles]
[FSH]
[LH]
Donadeu, Ginther,
Accelerating the Transition Period
*Use a lighting system
•After the last tx of P4, size of dominant follicle could be small or large
Synchronization dependent on development of follicle
•Spontaneous ovulations during luteal phase
Both hCG and GnRH achieve an ovulation within 48 hours on a 30-45mm follicle
-(on ~90% of all mares)
Inducing Ovulation
eFSH Bioniche (Equine Pituitary Extract)
• Contains LH and FSH
• Stimulate follicular development and advance ovulation in:
– Transitional (shorten period), acyclic & superovulate cycling mares
• Side effects
Good info less
relevant for
the
assignment
PGF2a
Prostaglandin Failure (may need a 2nd tx):
Bringing it all
together…
Breed
hCG
PGF2α (hCG) PGF2α
estrus
Day 1 6 14 18 20 22
Novak, 2007
ovulation
Progesterone PGF2α hCG
estrus
Day 1 12 16 18 21
Day 1 8 12 14 16 Novak, 2007
www.selectbreeders.com
Selection of a specific agent may
be based on:
Touch on these
• Cost – don’t need
too much
• Efficacy details
• Time of year
• Age of the mare
• Follicle size
• Previous use or success
• Clinician preference.
• Lofstedt R. 2004. Rational uses of hormones in broodmares. Professor of
Theriogenology Atlantic Vetereinary College.
• Lofstedt. R. 2003. The use of progesterone & estradiol in broodmares.