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Epidemiology

13000 In

new patients/day in world

India: Crossed 6 million 15-29yrs (40% women) emergency

32%

National

Definition of AIDS
Occurrence of one or more group of life threatening opportunistic infections, malignancies, neuralgic diseases and other specific illness in patients with human immunodeficiency virus (HIV) infection and / or with CD4 counts less than 200 /mm3 .

Etiologic Agent
HIV

belongs to the family of human retroviruses ( Retroviridae) Subfamily of Lentiviruses HIV-1 HIV-2 Major target is CD4 lymphocytes

CDC Classification of HIV


Early asymptomatic stage : CD4 cell count > 500/uL Intermediate stage : 200-500/ uL Advanced stage : <200/ uL

Oral Manifestations of AIDS

Classification
A.

Bacterial Infections GingivoPeriodontalDisease Linear gingival erythema (LGE) Necrotizing ulcerative periodontitis (NUP) Necrotizing stomatitis (NS)

B. Fungal Infections Candidiasis Other Fungi

C. Viral Infections Epstein-Barr Virus i. Oral Hairy Leukoplakia Herpes Simplex Virus i. Primary herpetic gingiva-stomatitis ii.Recurrent herpetic infection Variacella-Zoster Virus i.Herpes zoster Human Papiloma Virus i. Condyloma acuminatum ii. Multifocal epithelial hyperplasia Cytomegalovirus

D. Neoplasms 1. Kaposi's sarcoma 2. Lymphoma 3. Other neoplasms

E. Other Oral Lesions 1. Oral ulcers 2. Salivary gland enlargement

BACTERIAL INFECTION

Linear Gingival Erythema (LGE)

Necrotizing Ulcerative Periodontitis (NUP)

Necrotizing Stomatitis (NUS)

Fungal Infections

Oral Candidiasis
Pseudomembranous

candidiasis Atrophic candididiasis Hyperplastic candidiasis Angular cheilitis

Pseudomembranous Candidiasis

Atrophic Candidiasis

Hyperplastic Candidiasis

Angular chelitis

VIRAL INFECTIONS

Herpes Infection

Herpes Zoster

Condyloma Acuminatum

Epithelial hyperplasia

Hairy Leukoplakia

Neoplasms

Kaposi Sarcoma

Lymphoma

MISCELLANEOUS ORAL LESIONS

Oral Ulcer

Salivary gland disease

Tests for HIV Infection


Serological

HIV

test that detects antibodies to

- ELISA - Western Blot


NEVA-HIV

Test CD4 count

Occupational Exposure
Needle

stick injuries Cuts from other sharp Contact of eye, nose, mouth or skin with blood Most Exposures DoNot Result in infection

What to do on exposure
Do

not Panic Do not put cut /pricked finger into your mouth Immediate Measures Wash with soap and water Post exposure prophylaxis (PEP) should begin as soon as possible

Post Exposure Prophylaxis


Basic regime Zidovudine (AZT) +Lamivudine

SHUN THE DISEASE , NOT THE DISEASED

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