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Definition:
Any activity which does not correlate with the age and state of the patient. Abnormality could be of the following two main types of activity. 1. Non epileptiform Abnormal pattern 2. Epileptiform Pattern
Slow waves
1-focal slowing : Focal slowing means if slowing is restricted to only one hemisphere or specific region . The most prominent focal slowing is delta activity which ranges 0.5 3.5 Hz. Focal slowing may be continuous or intermittent. Continuous focal delta slowing is usually due to localized structural lesion (e.g tumor, stroke, abscess) Intermittent focal polyrhythmic delta slowing is non specific and could be due to migraine, trauma, post-ictal dysfunction etc.
Diffuse slowing:
Diffuse slowing/generalized slowing means synchronous and symmetrical slowing that appears in the whole background throughout the recording which indicates the involvement of both hemispheres of the brain or cerebral dysfunction. While reporting diffuse slowing, age, state (alertness) and medications of the patient must be known.
Amplitude asymmetry
Focal epileptiform activity (spike and sharp waves) consists of spike and sharp waves that appear on one or a few neighboring electrodes.
2. Generalized epileptiform activity: Epileptiform discharges (spike and sharp waves) that appear over most of all parts of both hemisphere and usually have symmetrical shape, amplitude and timing in corresponding areas.
Reference: Genetic evaluation and counseling for epilepsy Nature Reviews Neurology Review (01 Aug 2010)
Characteristics:
Periodic recurrence every 0.5-4.0 sec. With frequency of 1-2 sec. Etiology (Cause) acute infarction, CVA, tumor, anoxia and herpes simplex encephalitis, abscess etc.
pleds
5. Sub acute sclerosing panencephalities (SSPE) Characteristics Repetitive bursts of high voltage spike, sharp and slow wave complexes, recurring after every 4-15 seconds.
More prominent in awaking state. It relates with measles and myoclonic jerks Gen. but maximum over fronto central areas. Frequency ranges 4-15/sec
SSPE (Contd)
All the waves are Stereotyped (morphologically similar) Bilaterally synchronous Periodic high voltage 300-1500uv of sharp and slow waves complex with an irregular delta wave superimposed. It is an inflammatory disease that occurs in children and adolescents and is believed to be caused by measles virus.
Hypssarrythmia
(CJD)
contd
This is accompanied by physical problems such as speech impairment, jerky movements (myoclonus), balance and coordination dysfunction (ataxia), changes in gait, rigid posture, and seizures. EEG FINDINGS: Periodic discharges with sharp wave or a sharp triphasic complex. 100 -300msec duration Repetition rate of 0.5-2/sec. Shows severely disorganized & generalized synchrony background. Some cases show unilateral discharges over one hemispheres.