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DEVELOPMENT OF
MANDIBLE
INDIAN DENTAL ACADEMY
Leader in continuing dental education
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INTRODUCTION
The human mandible has no one design for
life. Rather it adapts & remodels through the
seven stages of life, from the slim arbiter of
things to come in infant, through a powerful
dentate machine & even weapon in the full
flesh of maturity, to the pencil thin, porcelain
like problem that we struggle to repair in the
adversity of old age.
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prenatal growth of mandible
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PRENATAL GROWTH OF
MANDIBLE
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prenatal growth of mandible
Nerveosteogenesis(Neurotrophic
factors)
Ectomesenchyme
interacts(36-38days iul)
Epi of 1
st
Arch
Osteogenic Memberane
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1 centre of ossification(6
th
week)
Inferior Alv Nerve
Incisive branch
around
below
Trough for acc dev Tooth buds
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prenatal growth of mandible
spread of IM ossification
dorsally and ventrally
body and ramus of the
mandible
presence of neuromuscular
bundleMandibular
foramen and canal and
mental foramen
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Fate of Meckel`s cartilage
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PRENATAL GROWTH OF
MANDIBLE
SECONDARY ACC CARTILAGES
(10
TH
-14
TH
WEEK I U L)
-condylar cartilage
-coronoid cartilage
-Mental ossicle cartilage
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PRENATAL GROWTH OF MANDIBLE
Secondary cartilage of coronoid process
Develop within temporalis muscle
Incorporated into IMB of ramus
Disappear before birth
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PRENATAL GROWTH OF
MANDIBLE
1/2 Cartilages
Mental ossicles
Intramembranous bone
syndesmosis
synostosis
Ossify (7
th
month of IUL)
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PRENATAL GROWTH OF
MANDIBLE
CONDYLAR CARTILAGE(10
TH
WEEK IUL)
Grow interstitially and oppositionally
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CONDYLAR CARTILAGE
1
ST
Evidence of endochondral bone (14
th
week iul)
Much of cartilage replaced with Bone by middle of fetal life
Upper end Growth cartilage and Articular cartilage
Changes Mand position and form
Growth at puberty peak b/n 12 -14yrs
Ceases 2o yrs of life
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NEONATAL MANDIBLE
RamusLow & wide
coronoidlarge & above
the condyle
Bodyopen shell
containing tooth buds
Mand canallow in the
body
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DIFFERENTIAL GROWTH
During fetal life
8weeks - MANDIBLE> MAXILLA
11weeks -MANDIBLE= MAXILLA
13-20weeks-MAXILLA>MANDIBLE
AT BIRTH
Mandible tends to be retrognathic
Early postnatal life -orthognathic
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POST NATAL GROWTH &
DEVELOPMENT OF
MANDIBLE
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MECHANISMS OF GROWTH
Growth Of The Mandible Primarily Involve
Bone remodeling
Process Of Bone Deposition And Resorption
Cortical drift
Combination of bone deposition and resorption resulting in
growth movement towards deposition surface
Displacement
Movement of whole bone as a unit
I) Primary displacement
II) Secondary displacement
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THEORIES OF GROWTH
GENETIC THEORY
Bone primary determinent
Cartilage primary determinent
The soft tissue matrix
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SUTURAL THEORY
Craniofacial growthsutures
Suture transplanted
Sutures pulled apart
Sutures compressed
Sutures are sites that react not primary
dereminants
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CARTILAGINOUS THEORY
Growth of maxilla Nasalseptum cartilage
Transplantation
Epiphyseal plate
Nasalseptal cartilage
Condylar cartilage
Removal of condyle
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FUNCTIONAL MATRIX THEORY OF
GROWTH
Skeletal growth occur as a response to
functional needs & mediated by the soft
tissue in which it is embedded
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ENLOWS EXPANDING V
PRINCIPLE
The growth movement &
enlargement of these Bones
occur towards the wide ends
of the V as a result of
differential deposition &
selective resorption
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ENLOWS COUNTERPART
PRINCIPLE
The growth of any given facial /cranial part
relates specifically to other structural &
geometric counterparts in the face &
cranium
Diff parts & counter parts
Maxillary & Mandibular arches
Middle cranial fossa breadth of Ramus
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Parts of Mandible derived From
1. INTRAMEMBRANOUS OSSIFICATION
* Whole body of mandible except the anterior part
* Ramus of mandible as far as mandibular foramen
2 . ENDOCHONDRAL OSSIFICATION
* Anterior portion of the mandible (symphysis)
* Part of ramus above the mandibular foramen
* Coronoid process
* Condylar process
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Timing of growth
Growth in width is completed 1
st
then
growth in length finally growth in height
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Growth in width
Intercanine width does not much after 12yrs
Both molar & bicondylar width show small
until the end of growth in length
Ant width stabilize earlier
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Growth in length
Continues through the period of puberty
Girls 14 -15 yrs
Boys 18 yrs
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POST NATAL GROWTH OF
MANDIBLE
Mandible Developmentally & Functionally
divisible into skeletal subunits
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Mandible undergoes largest amt of growth
postnatally and exhibits largest variability in
morphology
The main sites of postnatal growth
At condylar cartilages
Posterior border of rami
Alveolar ridges
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THE RAMUS
Key role of ramus in placing the corpus &
dental arch into ever changing fit with
growing maxilla & the faces limitless strl
variations
By Remodeling adjustments in Ramus
length & Ant post width.
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THE RAMUS
Relocates postly Deposition posteriorly
Resorption anteriorly
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LINGUAL TUBEROSITY
Direct Anatomic equivalent of Max tuberosity
Inaccessible to cephalometric studies
Major Growth & Remodeling site
Effective boundary b/n Ramus & corps
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LINGUAL TUBEROSITY
Deposition Postly & Medially
Resorption Below (Lingual fossa )
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Lingual Tuberosity
Remodels in post direction with
slight lateral shift
Lingual shift of Ant part of Ramus
Length of corpus
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Ramus to carpus Remodeling
Making room last
Molar
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Ramus to carpus Remodeling
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Coronoid process
Propellar like twist
Lingual side faces
posteriorly
superiorly
medially
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Coronoid process
Fallows V PRINCIPLE
V oriented vertically
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Coronoid process
v PRINCIPLE
VOriented horizontally
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Coronoid process
Coronoid process medially
to become post part of carpus
Buccal side Resorptive
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Ramus
Superior part of
ramus the area below
sigmoid
notch
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Ramus
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Antigonial notch
Size of the notch ed
downward rotation
Of carpus relative to the
Ramus
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The size of the notch depends upon Ramus Carpus junction
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Post edge Ramus is a major
growth site
Condyle grows obliquely upward &
backward
The angle of growth is variable
The gonial region is Anatomically
variable
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Mand Foramen midway b/n
Ant & post borders of Ramus
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The Mandibular condyle
Secondary cartilage
not a primary center of growth, but rather
* Secondary in Evolution
* Secondary in Embryonic origin
* Secondary in adaptive responses
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condyle
Cartilage is special nonvascular tissue
firm matrix unyielding to the pressure
Endochondral growth mechanism
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Provides pressure tolerant articular
contact
Multidimensional growth capacity in
response to ever changing developmental
conditions & variations
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Capsular layer of poorly
vascularised connective
tissue highly cellular
Chondroblasts cellular
proliferation
Chondroblasts
hypertrophy
Zone of resorptive &
Bone deposition
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Proliferative process
produces upward &
backward growth
movement
Multidirectional
proliferative capacity-
the arrangement of
daughter cells does
not reflect direction of
growth
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The cortical layer of IMB
continues on to the
condylar neck
Ant margin of condylar
neck depository
grows supely
post margin - depository
grows on to post barder
of ramus
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Lingual & Buccal
sides - Resorptive
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V-shaped cone of condylar neck growing
towards its wider end
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The condyle cant play king pin role of
Master center in pace-setting the growth
Bilaterally condyle-lacking mand occupy
normal Anatomic position
Condylar remodeling acts with displacement
as co-participants but not as driving force
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Current concept
Condylar cartilage does have some intrinsic
genetic programming
But extracondylar factors are needed to sustain
this activity
1)Intrinsic & extrinsic biomechanical forces
2)physiologic inductors
ENLOW;
amt of pressure inhibit the growth
amt of pressure stimulate the growth
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Mandible is less responsive to orthopedic
forces than maxilla
Mand orthopedics must modify growth
signals targeted at both ramus & condyle
to
be maximally effective
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MENTAL FORAMEN
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ALVEOLAR PROCESS
Adds ht & thickness to the
body of the Mand
Teeth absent fails to develop
Resorbs after tooth extraction
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Alveolar process
Maintain occlusal relationship during differential
mandibular & midfacial growth buffer zones
Maintains vertical height
Adaptive remodeling makes orthodontic tooth
movement possible
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Lingual movement of anteriors
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Mental protuberance
Formed by mental ossicles from accessory
cartilage and ventral end of Meckels cartilage
Poorly developed in infants
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Mental protuberance
Forms by osseous deposition
during childhood
Prominence is accentuated by
bone resorption above it
Reversal between 2 growth
fields
Concave convex
Reversal line could be High or
low
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Chin
Protrusive chin is unique human trait
More prominent in male
Less prominent in female
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Factors Affecting Growth
Systemic Factors
Genetic
Hormonal imbalance
Nutrition
Systemic illness or chronic illness
Localized alteration/ diseases of uterus
Systemic illness in mother
Drugs
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1. Vascular abnormality
2. Lymphatic disturbance
3. Neurologic disease
4. Local infection
5. Ear infection or mastoiditis
6. Ankylosis
7. Trauma or fracture
8. Birth injury
9. Habits
B) Local factors
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Anomalies of mandible
Some of the syndromes associated with
mandibular abnormality
1)Downs syndrome
2)Marfans syndrome
3)Turners syndrome
4)Kleinfelters syndrome
5) Pierre-robin syndrome
6) Treacher- collin syndrome
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Congenital
Agnathia
Micrognathia
Macrognathia
Facial hemihypertrophy
Facial hemiatropy
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Developmental
Infantile cortical hyperostosis
Achondroplasia
Torus mandibularis
Stafnes cyst
Odontogenic cyst
Odontogenic tumor
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Age changes of Mandible
At birth
Adult
Old age
1 Mental
foramen
2 Angle of the
mandible
3 coronoid &
condyloid
processes
4 Mandibular
canal
5 Symphysis
menti
Near the lower
border
Obtuse (180)
Coronoid is
larger & above
condyle
Runs little
above the
mylohyoid line
Present;two
halves united
fibrous tissue
Midway b/n upper
& lower border
Right angle
Condyle is above
the coronoid
Runs parallel to
the mylohyoid line
Reprasented by
faint ridge only in
the upper part
Near the upper border
Obtuse (140)
Condyle is above the
coronoid but in
extreme old age bent
backwards
Runs close to the
upper border
Not recognisable or
absent
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References
* Craniofacial embryology SPERBER
* Facial growth ENLOW
* Contemporary orthodontics PROFFIT
* Handbook of orthodontics MOYERS
* Principles and practice of orthodontics GRABER
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