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IV penicillin
IV Gentamicin
IV Cefotaxime
IV Clarithromycin
MANAGEMENT AND DISCUSSION
Subsequent management (D
1
)
bed in the acute side
QHT
Paracetamol 250mg (10 15 mg/kg) 6 hourly
Salbutamol 2mg 8 hourly
Chart RR 2 hourly
MANAGEMENT AND DISCUSSION
INVESTIGATIONS (D
1
)
WBC/DC
ESR
CXR (URGENT)
Mycoplasma antibodies
Sputum culture & ABST
Blood culture
Viral studies
MANAGEMENT AND DISCUSSION
WBC/DC
WBC 6700/L (6000- 15000)
DC Neutrophils 72%
Lymphocytes 20%
Monocytes 6%
PCV 40%
Platelet count 200000/ L)
Hb 10.1 g/dL (10.5 14 g/dL)
ESR 68mm 1
st
hour
CXR(D
1
)
MANAGEMENT AND DISCUSSION
D
1 afternoon
C. Penicillin 1.5 million units 6 hourly after ST
ST negative
D
1 5 pm
Fever and dry cough present
No vomiting
MANAGEMENT AND DISCUSSION
D
2 (11/11/2004)
Fever spikes present Ex- RR - 40/min
Dry cough present signs of consolidation
Hydration adequate No signs of effusion
Mx Chest physiotherapy
MANAGEMENT AND DISCUSSION
D
3 (12/11/2004)
Fever spikes Ex-RR- 48/min
Dry cough signs of consolidation
SOB & intercostal recession
no effusion
Hydration adequate
No chest pain
Mx IV Gentamicin 37 mg 8 hourly 3-5 mg/kg/day
MANAGEMENT AND DISCUSSION
Ototoxicity
Peak / trough blood levels
MRI
Why not done?
MANAGEMENT AND DISCUSSION
D
3 7.30pm
Fever spikes PR 150/min(80- 120)
Increased cough BP 90/70 mmHg
SOB O2 saturation 95%
Intercostal recessions
Mx
Nebulize- salbutamol 5mg with normal saline 4
hourly
MANAGEMENT AND DISCUSSION
D
4 (13/11/2004)
Fever spikes Ex-RR- 44/min
Dry cough signs of consolidation
SOB & intercostal recession
no effusion
Hydration adequate
No chest pain
MANAGEMENT AND DISCUSSION
D
5 (14/11/2004)
Fever spikes
Dry cough
Signs of consolidation
Mx- CXR
IV cefotaxime 250 mg 8 hourly
MANAGEMENT AND DISCUSSION
D
6 (15/11/2004)
No improvement in the clinical state
Mx
Blood culture
Stop physiotherapy
USS (right lower lobe consolidation with a small pleural effusion)
MANAGEMENT AND DISCUSSION
D
7 (16/11/2004)
No improvement in the clinical state
Mx
Blood for mycoplasma antibodies (private sector)
Inward cold agglutination test positive
IV Clarithromycin125mg/5% dextrose 100cc/12 hr
(125mg/12hr)
Omit Gentamicin and C. Penicillin
Hb- 9.5 g/dL
MANAGEMENT AND DISCUSSION
Inward cold agglutination test
o 1ml of blood
o Anticoagulated bottle
o Cooling 4
0
C
o 3-4 minutes
o Check for agglutination of RBC
nonspecific test
MANAGEMENT AND DISCUSSION
Serum bilirubin- total \direct\ indirect
Blood picture
Blood for cold agglutinin titres (1:32)
Coombs test
MANAGEMENT AND DISCUSSION
D
8(17/11/2004)
No significant clinical improvement
signs of consolidation
Blood culture negative
Mx
Start chest physiotherapy
MANAGEMENT AND DISCUSSION
D
9(18/11/2004)
Fever spikes present
Appetite improving
No sleep disturbances
Signs of consolidation present
USS (right lower lobe consolidation with a small pleural effusion,
no evidence of empyema)
MANAGEMENT AND DISCUSSION
D
9(18/11/2004)
Traced the mycoplasma antibody test in
MRI
Report - Significant titer suggestive of recent
mycoplasma infection
Mycoplasma
Further management
IV clarithromicin
CXR
Problems identified
Lower respiratory tract infection
Loss of preschool activities
Anxiety of the mother
Absence of father
Lack of proper spacing between
children
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