Depressed mood most of the day, nearly every day Markedly diminished interest or pleasure in almost all activities Significant weight loss when not dieting or weight gain or increase or decrease in appetite Insomnia or hypersomnia Psychomotor agitation or retardation Fatigue or loss of energy Feelings of worthlessness or excessive/inappropriate guilt Diminished ability to think or concentrate Recurrent thought of death, recurrent suicidal intention, suicide attempt or planning Symptoms above cause significant distress or impairment in social/occupation/function Late-life Depression One of the most common psychiatric problems in older adults 8-16% of older adults, 5-10% elderly in outpatient NOT A NORMAL PROCESS associated with aging Presenting symptoms is less typical more difficult to detect more on women Higher case of minor or subsyndromal depression Impairment of physical, cognitive, functional and social quality decreased quality of life Suicide, increased risk for cardiac mortality, relaps and life maintenance of depression Typical symptoms Somatic complaints of pain Unintentional change in weight/appetite, Chronic constipation Irritability, agitation Fatigue, headache, weakness insomnia, hypersomnia Geriatric Depression Scale Self-administered screening tool for measurement of depressive symptoms in older adults Distinguish between symptoms of dementia and depression Long form 30 question, higher score indicates more severe depression Short form 15 question, suggest more likely or highly likely to have depression Brink TL, Yesavage JA, Lum O, Heersema P, Adey MB, Rose TL: Screening tests for geriatric depression. Clinical Gerontologist 1: 37-44, 1982. https://www.stanford.edu/~yesavage/GDS.html Treatment Antidepressant SSRI, SNRI, tricyclic Electroconvulsive depression and suicidal thought not responding to therapy Psychotherapy cognitive behaviour therapy (CBT) Interpersonal therapy (IPT) focus on 4 component which may lead to depression Grief, interpersonal disputes, role transition, interpersonal deficits Reflective therapy Pyschodynamic Life-review therapy Reminiscence therapy Reference American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5 th ed (DSM-V).Washington: American Psychiatric Publishing; 2013. Blazer DG. Depression in late life: review and commentary. J Gerontol A Biol Sci Med Sci. 2003 Mar;58(3):249-65 Downing LJ1, Caprio TV, Lyness JM. Geriatric psychiatry review: differential diagnosis and treatment of the 3 D's - delirium, dementia, and depression. Curr Psychiatry Rep. 2013 Jun;15(6):365. Frank C. Pharmacological treatment of depression in the elderly. Can Fam Physician. 2014 Feb;60(2):121-6. Cognitive Impairment in the elderly recognition, diagnosis and management. Available from: http://www.bcguidelines.ca/guideline_cognitive.html Geriatric depression scale. Available from: http://www.stanford.edu/~yesavage/GDS.html