ANTIHYPERTENSIVE

MEDICATIONS
Classification… Name… Brand…
Action… Side effects…
Contraindication… Nursing Consideration
ANTIHYPERTENSIVE
MEDICATIONS
 ACE INHIBITORS
 BETA BLOCKERS
 CALCIUM CHANNEL BLOCKERS
 DIURETICS
 EMERGENCY
ANTIHYPERTENSIVES
ACE INHIBITORS

 RIL or PRIL
 The ACE inhibitors block the action of the
angiotensin-converting enzyme in the lungs so
that angiotensin I is not converted into
angiotensin II. The production of this powerful
blood vessel constrictor is thereby prevented.
The blood vessels thus remain widened, which
results in lowering of the blood pressure.
ACE INHIBITORS

 RIL or PRIL… VASODILATORS

 A-CCUPRIL
 C-APTOPRIL
 E-NALAPRIL
 Z-ESTRIL
ACE INHIBITORS

 RIL or PRIL… VASODILATORS

 SIDE EFFECTS…
 HYPOTENSION… check BP and
HEART RATE… Tachycardia…

 Management… Give 1 HOUR Before

MEALTIME!!!
ACE INHIBITORS
 RIL or PRIL… VASODILATORS
 ADVERSE EFFECTS…
 Angioedema
 Rash with pruritus
 Dry cough

 CONTRAINDICATIONS… Renal
failure… use with CAUTION…
BETA BLOCKERS
 OLOL…

 Beta-blockers are drugs that bind to beta-

adrenoceptors and thereby block the
binding of norepinephrine and epinephrine
to these receptors. This inhibits normal
sympathetic effects that act through these
receptors. Therefore, beta-blockers are
sympatholytic drugs.
BETA BLOCKERS

 OLOL…

 TimOLOL
 NadOLOL
 SotaLOL
 PropanOLOL
BETA BLOCKERS

 OLOL…

 SIDE EFFECTS
 HYPOTENSION…
 BRADYCARDIA…
BETA BLOCKERS

 OLOL…

 ADVERSE EFFECTS
 BRONCHOSPASM
 CHF… Blocks Epinephrine and
Norepinephrine…
BETA BLOCKERS

 OLOL…

 CONTRAINDICATIONS
 Bronchial Asthma
 CHF
 COPD
CALCIUM CHANNEL
BLOCKERS

 Decrease CORONARY and

MYCORDIAL SPASM…
 Promotes VASODILATION...
 Used as ANTIARRHYTMIC…
 Used for CHEST PAIN
CALCIUM CHANNEL
BLOCKERS
 CAlan
 CArdizem
 CAlcobloc
 Nifedipine
 Felodipine
 Amlodipine
CALCIUM CHANNEL
BLOCKERS

 SIDE EFFECTS
 Hypotension
 Bradycardia
CALCIUM CHANNEL
BLOCKERS
 ADVERSE EFFECTS
 Signs and Symptoms of CHF…
 Peripheral edema…
 Shortness of breath…
 Jugular vein distension…
DIURETICS

 Excretion of EXCESSIVE WATER and

ELECTROLYTES…
DIURETICS
 Aldactone… K sparring… NO ABC…
Apple… Avocado… Apricot… Banana…
Baked potato… Cantaloupe…
 Bumex
 Chlorthiazide
 Dyrenium
 Edecrin
 Fusid… Furosemide…
DIURETICS

 Management
 Monitor… Vital signs esp BP…
Weight… I and O… Urine Output…
 Monitor K… increased… Cardiac
arrhythmia… Cardiac arrest…

 REPORT TINNITUS… OTOTOXICITY…

EMERGENCY ANTI
HYPERTENSIVE
 APRESOLINE… AGN… AUTONOMIC
DYSREFLEXIA… Malignant HTN/CRISIS…
Diastolic of 120 mmHg and up…
 PHENTOLAMINE… SHORT ACTING for
PHEOCHROMOCYTOMA..
 DIBENZYLINE…LONG ACTING for
PHEOCHROMOCYTOMA

INDICATIONS OF EFFECTIVENESS…
DECREASED BP… DECREASED
DIAPHORESIS…