Phagocytes

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Immunology > Phagocytes
Phagocytes
Phagocyte Migration and Phagocytosis
Microbial Evasion of Phagocytosis
www.boundless.com/microbiology
Phagocyte Migration and Phagocytosis

Phagocytosis is needed to clear many things from a body, especially during an
infection, when specialized cells "eat" things such as cellular debris or invading
microbes.
There are different cells that can engulf or phagocytose material in the body,
these include macrophages, dendritic cells, and neutrophils.
Phagocytic cells can migrate to a location where they are needed, through
signaling events in the body.
Neutrophils
View on Boundless.com
www.boundless.com/microbiology/textbooks/boundless-microbiology-textbook/immunology-11/phagocytes-137/phagocyte-migration-and-phagocyto
sis-701-5425
Microbial Evasion of Phagocytosis

The adaptive immune response is slower to develop than the innate immune
response, but it can act much more powerfully and quickly than the innate
immune response against pathogens that it has seen before.
B and T cells are lymphocytes, or white blood cells, which are able to recognize
antigens that distinguish "self" from "other" in the body.
B and T cells that recognize "self" antigens are destroyed before they can
mature; this helps to prevent the immune system from attacking its own body.
T cell by SEM
View on Boundless.com
www.boundless.com/microbiology/textbooks/boundless-microbiology-textbook/immunology-11/phagocytes-137/microbial-evasion-of-phagocytosis702-12124
Appendix
Immunology
Key terms
antigen a substance that binds to a specific antibody; may cause an immune response
B cell a lymphocyte, developed in the bursa of birds and the bone marrow of other animals, that produces antibodies and is
responsible for the immune system
macrophage A white blood cell that phagocytizes necrotic cell debris and foreign material, including viruses, bacteria, and
tattoo ink.It presents foreign antigens on MHC II to lymphocytes.Part of the innate immune system.
metachromatic granule a granular cell inclusion present in many bacterial cells, having an avidity for basic dyes and causing
irregular staining of the cell
neutrophil Neutrophil granulocytes are the most abundant type of white blood cells in mammals and form an essential part of
the innate immune system.
T cell a lymphocyte, from the thymus, that can recognize specific antigens and can activate or deactivate other immune cells
Immunology
T cell by SEM
This scanning electron micrograph shows a T lymphocyte.T and B cells are indistinguishable by light microscopy, but can be differentiated experimentally
by probing their surface receptors.
Connexions. "Adaptive Immunity." CC BY 3.0 http://cnx.org/content/m47434/latest/ View on Boundless.com
Immunology
T cell receptors (TCRs)

A T cell receptor spans the membrane and projects variable binding regions into the extracellular space to bind processed antigens via MHC molecules
on APCs.
Connexions. "Adaptive Immune Response." CC BY 3.0 http://cnx.org/content/m44821/latest/ View on Boundless.com
Immunology
B cell receptors
B cell receptors are embedded in the membranes of B cells and bind a variety of antigens through their variable regions, or antibodies.The signal
transduction region transfers the signal into the cell.
Connexions. "Adaptive Immune Response." CC BY 3.0 http://cnx.org/content/m44821/latest/ View on Boundless.com
Immunology
Exposure to sunlight causes tattoos to fade. The sunlight does not

affect the tattoo directly but rather kills cells around the tattoo, this
recruits phagocytes through ______, the phagocytes while there
will then absorb tattoo ink.
A) macrophage
B) phagocytosis
C) migration
D) invading microbes
Immunology
Exposure to sunlight causes tattoos to fade. The sunlight does not

affect the tattoo directly but rather kills cells around the tattoo, this
recruits phagocytes through ______, the phagocytes while there
will then absorb tattoo ink.
A) macrophage
B) phagocytosis
C) migration
D) invading microbes
Boundless - LO. "Boundless." CC BY-SA 3.0 http://www.boundless.com/
Immunology
Which of the following statements best describes the difference

between T cell receptors (TCRs) and B cell receptors (BCRs)?
A) TCRs are present on the inside of cells, whereas BCRs are present on
the outside of cells.
B) TCRs contain antibodies, whereas BCRs contain do not.
C) TCRs help initiate the complement cascade, whereas BCRs help
recruit phagocytes.
D) TCRs recognize several antigen/MHC combinations, whereas BCRs
only recognize one specific antigen.
Immunology
Which of the following statements best describes the difference

between T cell receptors (TCRs) and B cell receptors (BCRs)?
A) TCRs are present on the inside of cells, whereas BCRs are present on
the outside of cells.
B) TCRs contain antibodies, whereas BCRs contain do not.
C) TCRs help initiate the complement cascade, whereas BCRs help
recruit phagocytes.
D) TCRs recognize several antigen/MHC combinations, whereas BCRs
only recognize one specific antigen.
Boundless - LO. "Boundless." CC BY-SA 3.0 http://www.boundless.com/
Immunology
Attribution
Wikipedia. "Phagocyte." CC BY-SA 3.0 http://en.wikipedia.org/wiki/Phagocyte#Phagocytosis
Wikipedia. "Phagocyte." CC BY-SA 3.0 http://en.wikipedia.org/wiki/Phagocyte#Phagocytosis
Wikimedia. "NeutrophilerAktion." CC BY-SA 3.0 http://commons.wikimedia.org/wiki/File:NeutrophilerAktion.png
Wikipedia. "Neutrophils." CC BY-SA 3.0 http://en.wikipedia.org/wiki/Neutrophils
Boundless Learning. "Boundless." CC BY-SA 3.0 http://www.boundless.com//microbiology/definition/metachromatic-granule
Wiktionary. "macrophage." CC BY-SA 3.0 http://en.wiktionary.org/wiki/macrophage
Wiktionary. "neutrophil." CC BY-SA 3.0 http://en.wiktionary.org/wiki/neutrophil
Connexions. "Adaptive Immunity." CC BY 3.0 http://cnx.org/content/m47434/latest/
Wikipedia. "Major histocompatibility complex." CC BY-SA 3.0 http://en.wikipedia.org/wiki/Major_histocompatibility_complex
Wikipedia. "MHC class II." CC BY-SA 3.0 http://en.wikipedia.org/wiki/MHC_class_II
Wiktionary. "T cell." CC BY-SA 3.0 http://en.wiktionary.org/wiki/T+cell
Wiktionary. "B cell." CC BY-SA 3.0 http://en.wiktionary.org/wiki/B+cell
Wiktionary. "antigen." CC BY-SA 3.0 http://en.wiktionary.org/wiki/antigen

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Immunology > Phagocytes

Immunology > Phagocytes

Phagocyte Migration and Phagocytosis

Immunology > Phagocytes

Microbial Evasion of Phagocytosis

T cell receptors (TCRs)

Exposure to sunlight causes tattoos to fade. The sunlight does not

Exposure to sunlight causes tattoos to fade. The sunlight does not

Which of the following statements best describes the difference

Which of the following statements best describes the difference

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