Академический Документы
Профессиональный Документы
Культура Документы
oDiagnosis
practice
o Emphasis on confirming the diagnosis of
asthma, to avoid both under- and overtreatment
oAsthma control
What is
Definition
heterogeneous disease
characterized by chronic
airway inflammation
Definition
Wheeze
Chest
Tightnes
s
Shortne
ss of
Breath
Cough
variable
expiratory
airflow
limitation
PATHOGENESIS OF
o HOST FACTORS
o Genetic
predisposing to atopy
predisposing to airway hyperresponsiveness
o Obesity
o Sex
o ENVIRONMENTAL FACTORS
o Allergens
o Infections (predominantly viral)
o Occupational sensitizers
o Tobacco smoke
o Air pollution
o Diet
MECHANISMS OF ASTHMA
o Airway inflammation is a
consistent feature
episodic
o affects all airways but is more
pronounced in the medium-sized
bronchi
NE
W
Patterns of Respiratory
Symptoms that are
characteristic of asthma
Patterns of Respiratory
Symptoms that are
characteristic of asthma
Chest pains
o Other options
o Other options
*For children 6-11 years, theophylline is not recommended, and preferred Step 3 is medium dose ICS
**For patients prescribed BDP/formoterol or BUD/formoterol maintenance and reliever therapy
o ADULTS/ADOLESCENTS
*For children 6-11 years, theophylline is not recommended, and preferred Step 3 is medium dose ICS
**For patients prescribed BDP/formoterol or BUD/formoterol maintenance and reliever therapy
o ADULTS/ADOLESCENTS
o low dose ICS/formoterol as
maintenance
regimen*
and reliever
OR
needed SABA
*For children 6-11 years, theophylline is not recommended, and preferred Step 3 is medium dose ICS
**For patients prescribed BDP/formoterol or BUD/formoterol maintenance and reliever therapy
moderate
or severe allergic asthma
(uncontrolled on Step 4 treatment)
o Add-on low dose oral corticosteroids
(7.5mg/day prednisone equivalent)
TIOTROPIUM IN
ASTHMA
THANK YOU~