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Secondary intention
Not reapproximated
Defect fill in with granulation tissue and later reepithelized
Delay healing; Require special dressing and
treatment
Gurtner GC. Wound Healing: Normal and Abnormal. In: Grabb and Smiths Plastic Surgery, 6 th edition.
Lippincot William and Wilkins. 2007;2:15-22
Clean and Debridement; expect the wound to heal with secondary intention
Chronic Wound
Persist beyond 4-6 weeks
Include wound that present for months or years
Gurtner GC. Wound Healing: Normal and Abnormal. In: Grabb and Smiths Plastic Surgery, 6 th edition.
Lippincot William and Wilkins. 2007;2:15-22
Inflammatory phase
Immediately following tissue injury
Functional priorities:
Hemostasis
Removal of dead and devitalized tissue
Prevention of colonization and invasive
infection by microbial pathogens
Proliferative phase
Occurred 4-21 days following injury
Replace of fibrin matrix by granulation
tissue; composed of three cells:
Fibroblasts
Macrophages
Endothelial cells
Keratinocytes migration
Re-epithelialization
Gurtner GC. Wound Healing: Normal and Abnormal. In: Grabb and Smiths Plastic Surgery, 6 th edition.
Lippincot William and Wilkins. 2007;2:15-22
Remodeling phase
Last from 21 days and up to 1 years
Programmed regression of blood
vessels and granulation tissue
Wound contraction
Collagen remodeling
Gurtner GC. Wound Healing: Normal and Abnormal. In: Grabb and Smiths Plastic Surgery, 6 th edition.
Lippincot William and Wilkins. 2007;2:15-22
Lorentz HP. Longaker MT. Wounds: Biology, Pathology, and Management. In: Norton, Bollinger, Chang et
al. Surgery: Basic Science and Clinical Evidence. Springer-Verlag New York. 2001;12:233-235
Buergers disease
Atherosclerosis obliterans
Digital gangrene due to Raynauds disease
Wound culturing
Wound dressing
Wound dressing
The optimal open wound dressing:
Maintains a moist, clean environment that
prevents pressure and mechanical trauma,
reduces edema, stimulates repair, and
inexpensive.
Less frequent dressing changes and
prevention of skin irritation
Wound dressing
Numerous dressing products
Plain gauze and normal saline (moist to dry
gauze) with or without antibiotic ointment remain
the simplest and least expensive dressing
Major disadvantages:
Frequent need for changes
Painful changes
Lorentz HP. Longaker MT. Wounds: Biology, Pathology, and Management. In: Norton, Bollinger, Chang et
al. Surgery: Basic Science and Clinical Evidence. Springer-Verlag New York. 2001;12:233-235
Case
Case
Case
Day 29
Day 4
Case
Daily wound care is only application of saline moist gauze and dry gauze