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DEFINITION CONT.
Hemophilia is a genetic disorderusually
inheritedof the mechanism of blood
clotting. Depending on the degree of the
disorder present in an individual, excess
bleeding may occur only after specific,
predictable events (such as surgery, dental
procedures,
or
injury),
or
occur
spontaneously, with no known initiating event
http://medical-dictionary.thefreedictionary.com/hemophilia
DEFINITION CONT.
Haemophilia(/himfli/;
also
spelledhemophiliainNorth America, from
theGreekhaima 'blood' andphilia
'love'[1]) is a group ofhereditarygenetic
disordersthat impair the body's ability to
controlbloodclotting orcoagulation, which
is used to stop bleeding when ablood
vesselis broken.
https://en.wikipedia.org/wiki/Haemophilia
CLASSIFICATION
HEMOPHILIA A
Haemophilia Ais a recessive X-linked genetic
disorder involving a lack of functional
clotting Factor VIII and represents 80% of
haemophilia cases.
HEMOPHILIA B
Haemophilia Bis a recessive X-linked genetic
disorder involving a lack of functional
clotting
Factor
IX.
It
comprises
approximately 20% of haemophilia cases
HEMOPHILIA C
Haemophilia
Cis
anautosomalgenetic
disorder (i.e.notX-linked) involving a lack of
functional clottingFactor XI. Haemophilia C
is
not
completely
recessive,
asheterozygousindividuals
also
show
increased bleeding.
EXCESSIVE BLEEDING
Signs of external bleeding may include:
Bleeding in the mouth from a cut or bite or from
cutting or losing a tooth
Nosebleeds for no obvious reason
Heavy bleeding from a minor cut
Bleeding from a cut that resumes after stopping
for a short time
CONT.
Signs of internal bleeding may include:
Blood in the urine (from bleeding in the kidneys
or bladder)
Blood in the stool (from bleeding in the
intestines or stomach)
Large bruises (from bleeding into the large
muscles of the body)
PATHOPHYSIOLOGY
TREATMENT
Certain analgesics, such as nonsteroidal antiinflammatory drugs (eg, Tylenol and Ibuprofen )
CONT.
PUSTAKA LIST