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previously called NONINSULIN-DEPENDENT

DIABETES MELLITUS, NIDDM, or MATURITY-
ONSET DIABETES
Y   
O Type2 diabetes mellitus is a
group of disorders
characterized by
› hyperglycemia and
› associated with microvascular (ie,
retinal, renal, possibly
neuropathic), macrovascular (ie,
coronary, peripheral vascular),
and neuropathic (ie, autonomic,
peripheral) complications
O the most common form of diabetes
mellitus
O over 90-95% of these cases can be
prevented
O it remains for adults the leading cause
of related complications such as
blindness, non-traumatic amputations
and chronic kidney failure requiring
dialysis.
O usually starts in people over age 40
who are overweight
O can occur in people who are not
overweight
O Sometimes referred to as "ADULT-
ONSET DIABETES³
O has started to appear in children
because of the rise in obesity in
young people
O is slightly more common in older
women than men.
6

O caused by R
R 
R
 , in which
the body does not properly use
insulin.
O is thought to result from a
combination of genetic factors along
with lifestyle factors such as obesity,
high alcohol intake, and being
sedentary.
O Conditions that damage or destroy
the pancreas, such as pancreatitis
(inflammation), pancreatic surgery, or
certain industrial chemicals
O polycystic ovaries are highly
associated with diabetes
O certain drugs can also cause
temporary diabetes, including
corticosteroids, beta blockers, and
phenytoin.
O Certain genetic and hormonal
disorders are associated with or
increase the risk of diabetes.
 O Deficient insulin production
O "
O 9yperglycemia
O "
O Inc. concentration of blood glucose
O "
O Plucosuria
O "
O Excess glucose excreted in urine
O "
O Excess fluid loss
O "
O Polyuria / Polydipsia (thirst)
 O Insulin deficiency
O "
O Impaired metabolism of C9ON and
fats
O "
O „eight loss
O "
O Decreased storage of calories
O "
O Polyphagia (excessive eating)
O 



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