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Medication-Assisted Treatment
Medication-Assisted Treatment
Approach that uses FDA-approved drugs, often in combination with
psychosocial treatments, for patients with opioid use disorders.
The FDA has approved three medications in several different
formulations for the treatment of opioid use disorder:
Methadone
Buprenorphine
Naltrexone (oral or injectable)
Highly effective
Medication-Assisted Treatment
Highly effective:
Illicit opioid use is reduced by 40-70 percent on
average
Risk of HIV infection is reduced six fold and risk of
infection with hepatitis C and B drops
Methadone decreases opioid overdose by 40-80
percent
Employment increases
Reduced criminal activity
Medication-Assisted Treatment
Medication-Assisted Treatment
Medication-Assisted Treatment
< 20% of people with an opioid use disorder receive treatment in
any given year
Jones, CM, et al. National and State Treatment Need and Capacity for Opioid Agonist Medication-Assisted
Treatment.American Journal of Public Health: August 2015, Vol. 105, No. 8, pp. e55-e63.
Jones, CM, et al. National and State Treatment Need and Capacity for Opioid Agonist Medication-Assisted
Treatment.American Journal of Public Health: August 2015, Vol. 105, No. 8, pp. e55-e63.
Criminal justice
Diversion
Drug courts
MAT
Return to the community
Parity Enforcement
people received
naloxone kits from
community outreach
programs,1996 and
2014
overdoses were
reversed using those
kits, according to the
CDC
No safe havens for injecting illegal drugs exist in the US, but
it is being considered in some states, such as CA and MD
www.pewtrusts.org/PRRreport
www.pewtrusts.org/PRRreport
www.pewtrusts.org/PRRreport
MN: estimated cost savings of $1.2 million in the first year of patient enrollment
Reductions in prescriptions, emergency room utilization, and clinic visits
Average savings of $4,800 per patient
OK: decreases in pre- and post- enrollment in the mean monthly average for:
Narcotic prescriptions (from 2.16 to 1.32),
Emergency department visits (from 1.26 to 0.81),
Number of pharmacies visited (from 2.05 to 0.89), and
Number of prescribers seen (from 2.48 to 1.63)
Prescription Drug Monitoring Program Training and Technical Assistance Center, PDMP Legislation & Operational Dates,
http://www.pdmpassist.org/content/pdmp-legislation-operational-dates
Prescription Drug Monitoring Program Training and Technical Assistance Center, PDMP Legislation & Operational Dates,
http://www.pdmpassist.org/content/pdmp-legislation-operational-dates
https://www.whitehouse.gov/sites/default/files/ondcp/policy-and-research/2015_national_drug_control_strategy_0.pdf
Unsolicited Reporting
Prescriber Use Mandates
Delegation
Data Timeliness
Streamlined Enrollment
Educational and Promotional Initiatives
Health Information Technology Integration
Enhanced User Interfaces
Unsolicited Reports
Available at http://www.pdmpassist.org/pdf/Prescribers_Sol_Unsol_Reports.pdf
Massachusetts Assessment of
Unsolicited Reporting
Available at http://www.namsdl.org/IssuesandEvents/
2015%20Annual%20Review%20of%20Prescription%20Monitoring%20Programs%20graphics.pdf
Note: Multiple provider episodes defined as patients using five or more prescribers
and five or more dispensers within the month. Source: New York PDMP
Grants
Federal (Bureau of Justice Assistance, Centers for Disease Control
and Prevention)
Private (National Association of State Controlled Substances
Authorities)
Available at http://www.pdmpassist.org/pdf/PDMP_Funding_Options_TAG.pdf
Methadone
Methadone
A synthetic opioid that has been used since the 1960s to treat
heroin addiction by mitigating withdrawal symptoms1
In the mid-1990s, methadone began to be increasingly prescribed
for the treatment of chronic noncancer pain1
Accounts for just two percent of opioid pain reliever prescriptions,
yet is implicated in nearly one third of these deaths2
Centers for Disease Control and Prevention, Vital Signs: Risk for Overdose from Methadone Used for Pain Relief United States, 19992010, Morbidity and Mortality
Weekly Report 61, no. 26 (2012): 493-497, http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6126a5.htm
2 Centers for Disease Control and Prevention, Vital Signs: Prescription Painkiller Overdoses: Use and Abuse of Methadone as a Painkiller,
http://www.cdc.gov/vitalsigns/pdf/2012-07-vitalsigns.pdf
1
The Pew Charitable Trusts, Prescription Drug Abuse Epidemic: Methadone, (2014), http://www.pewtrusts.org/en/research-and-analysis/fact-sheets/2014/08/prescription-drugabuse-epidemic
Centers for Disease Control and Prevention, Vital Signs: Prescription Painkiller Overdoses: Use and Abuse of Methadone as a Painkiller,
http://www.cdc.gov/vitalsigns/pdf/2012-07-vitalsigns.pdf