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PENELITIAN
DESAIN KOHORT
Pembimbing:
dr. Djap Hadi S.,M.Kes
Disusun oleh:
Sharania Manivannan
11-2014 - 182
TOPIC
Prospective Cohort Study of
Green Tea Consumption and
Colorectal Cancer Risk in
Women
PROBLEM
Tea
and
its
antioxidative,
constituents
anti-
have
inflammatory,
shown
and
AIM
The inverse association with regular
tea drinking was observed for both
colon and rectal cancers.This study
suggests that regular consumption
of green tea may reduce CRC risk in
women
DESIGN
Analitic
Prospective cohort study.
VARIABLE
Depende
nt
Independ
ent
Colorectal
cancer in
women
Green tea
consumpti
on
POPULATION DAN
SAMPLE74,942 women
between 1996
and 2000 from
seven urban
communities of
Shanghai
Women aged
40 to 70
years at
baseline.
CRITERIA
INKLUSIF :
demographic characteristics, lifestyle and dietary habits,
medical
history,
and
family
history
of
cancer.
of
cancer,
diabetes,
or
familial
adenomatous
METHODS AND
MATERIALS
Questionaires
The death certificate data, medical charts
from hospitals, endoscopy, radiography
(barium-air double contrast radiography
and computed tomographic scans) or
ultrasound.
CONCEPTUAL
FRAMEWORK
Type and
amount of tea
Age she
started such
habit
Drank tea
regularly (at
least thrice
per week
lasting at
least 6
months)
Tea leaves
consumed
past year
Colorect
al
Cancer
Risk in
Women
Current status
of tea
consumption.
DATA ANALYSIS
STATISTIC ANALITIK- multivariate
The Cox proportional hazards model was
used to compute relative risks (RR) of
developing CRC associated with green tea
consumption and their 95% confidence
intervals (95% CI) after adjusting for
potential confounding variables.
HASIL
RESULT
RESULT
CONCLUSION
In this large population-based prospective
cohort
study,
we
found
that
regular
PROPOSITION
This prospective cohort study among women
in Shanghai provides one of the strongest
pieces of evidence in humans that regular
consumption of green tea may confer a
protection against CRC.
These findings are consistent with data
from in vitro and in vivo experiments,
indicating that tea may serve as an
effective chemopreventive agent
TERIMA KASIH