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Obstructive Pulmonary
Diseases (COPD)
Mini Lecture 2
Module: Tobacco effects on
respiratory system
CORE SLIDES
OPTIONAL SLIDES
Pathology of COPD
Basic mechanism: innate and adaptive inflammatory
immune response
Airway limitation in COPD patients can occurred through:
Infiltration of inflammatory cells and occlusion of airway
by inflammatory exudates
Thickening of airways wall due to repair and
remodeling process hyperactivity of epithelial cells
Decreased of elastic recoil pressure at respiratory
bronchioles
(Hogg and Timens, 2009)