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Introduction
Chapter19
The acetoacetic ester and malonic acid syntheses usedicarbonyl compounds for carbon-carbon bond forming reactions
Chapter19
Esters
Chapter19
Chapter19
Chapter19
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Chapter19
Chapter19
Introduction
Chapter19
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The acetoacetic ester and malonic acid syntheses usedicarbonyl compounds for carbon-carbon bond forming reactions
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Chapter19
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Example:
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If -halo esters are used to alkylate the enolate, -keto acids are
obtained
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Carbon
Chapter19
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Alkylation of diethylmalonate, hydrolysis of the diester to the dicarboxylic acid, and decarboxylation can be used to synthesize
mono- and disubstituted acetic acids
The mechanism is analogous to that for the acetoacetic ester
synthesis
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Examples
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