JOURNAL CLUB:

INFORMATION RESOURCES FOR CLINICAL RESEARCH

Dr.Junaid Nazar
MBBS,MPH (UK),FRSPH (UK), MD Internal medicine (UK), MSc Neprhology (UK)
Nephrologist/Public Health Practitioner
Shifa International Hospital, Islamabad, Pakistan

OVERVIEW
Introduction and Definitions
Why literature Review ?
Literature interpretation
Literature search resources
Citation and references

DEFINITION OF LITERATURE REVIEW

The process of reading, analyzing, evaluating, and summarizing scholarly

materials about a specific topic

The results of a literature review may be compiled in a report or they may

serve as part of a research article, thesis, or grant proposal.

http://grammer.about.com/od/il/g/luteraturereviewterm.htm

LITERATURE REVIEW

Background
Every step on your research
Study question ( PICOT)
Ethics Informed consent
IRB Researchs Proposal
Methods :
Measurements and procedure
Variables and outcomes
Validity and reliability

journey

Sample size calculation

Statistical tests and data analysis

Results

Limitations and discussions

Manuscript writing

WHAT ARE THE RESOURCES ?

Primary literature

Secondary literature

6S APPROACH
2-SUMMARIES

Text books
Dynamed (www.dynamicmedical.com)
UpToDate: (http:/www.uptodate.com)
PIER : (http:/www.pier.acponline.org/index.html)
Clinical evidence : (http:/clincalevidence.com)
EBM guidelines :
(http:/www.interscience.wiley.com/cgibin/mrwhome/112605734/HOME)

5S APPROACH
3-SYNOPSES OF SYNTHESIS

Cochrane database of systematic review (OVID)

(www.intersceince.wiely.com/cgi/bin/mrwhome/106568753/HOME)

DARE ( Database of Review of Effects) FREE

(www.crd.york.ac.uk/crd/crddatabase.htm#DARE)

5S APPROACH
4- SYNOPSES AND 5-SYNTHESIS

ACP journal Club: (http:/www.acpjc.org/)

InfoPOEMS :(http:/www.infopoems.com/

5S APPROACH
6- STUDIES

MEDLINE :(OVID Technology)

PubMed :(www.ncbi.nih.gov)

CINHAL: Cumulative Index to Nursing and Allied Health

Literature (www.cinhal.com./prodsvcs/prodsvcs.htm)

EMBASE : Experta Medica Biomedical database

Cochrane Controlled Trials Registry :

www.cochrane.org/reviews/clibintro.htm)

6- OTHERS

Google / Google Scholar

Msn/Yahoo

Sumsearch (Cochrane systematic review, PubMED,DARE)

(http:/sumsearch.uthsca.edu/)

TRIP: (http://www.tripdatabase.com)

APTA : American Physical Therapy Association

AOTA : American Occupational Therapy Association

LIMITATIONS TO LITERATURE REVIEW

Availability of Resources

Shear volume of research based evidence

Time consuming

Professional Skills in searching and appraisal

Application to daily practice

 How to keep up with Research of your Interest?

Email Alert
If nothing works out PLEASE TRY THIS LINK

SCI_HUB.CC

HOW TO FIND ARTICLES ON PUBMED?

1.Focus your question and identify the main concept

2.Show me the details

3.Remember the Mesh

4.Combine terms with ANDs and OR on advance Search

5.Use limits at the end

1.FOCUS YOUR QUESTION AND IDENTIFY THE MAIN CONCEPT

Patients problem
Intervention
Comparison
Outcome

EXAMPLE

Vaccinating health care workers against the flu to prevent patients infections

Health care workers

Influenza vaccine

Patient infection

COMBINE TERMS WITH ANDS ORS ON ADVANCE

RESEARCH

AND=Find citations that have BOTH terms/concepts

OR= Finds citations that have either terms/concepts

EXERCISE

A 30 years old male is diagnosed with depression. He would prefer to try alternative
medicine rather than SSRI. You believe that his disorder would be improved with as
SSRI, but he wants to know if St.John Wort could be effective for reducing symptoms.

Thank You