Effects of green tea catechin extract on

serum lipids in
postmenopausal women: a randomized,
placebo-controlled
clinical trial
Yunitia Anjani
30101307103
Sgd 01

background
Cardiovascular disease (CVD) remains the
primary cause of death in the United States and
worldwide. Hyperlipidemia is considered to be a
major risk factor for CVD, and currently a high
percentage of US women have elevated
concentrations of total cholesterol (TC) and LDL
cholesterol (45.0% and 32.0%, respectively).
Green tea as a dietary factor has been shown to
lower the risk of a number of chronic diseases,
including heart disease
Blood lipid concentrations in postmenopausal
women are of interest due to their increased risk
and incidence of developing heart disease

Apakah tujuan uji klinik?

Rancangan uji klinik?

Each participant was instructed to

take 2 capsules (either GTE or
placebo) in the morning after
breakfast and 2 capsules in the
evening after dinner.

Bagaimana kriteria pasien?

Apa obat/pengobatan yang diteliti

dan apa kontrol/pembandingnya?

Alokasi perlakuan terapi?

Kriteria penilaian respon?

 Blood collection and processing

Serum collected at the clinic for
analysis was separated from whole
blood by centrifugation at 1500 3 g
for 25 min at 48C, then separated
into 1.5-mL aliquots and stored at
-80 C until analised

Analisis statistik?

Makna klinik hasil uji

etika
Subjek penelitian telah
menandatangani informed consent
setelah menerima penjelasan baik
dari telepon maupun penjelasan
secara langsung.

Kesimpulan uji klinik