Quiz

Pharmacology

 Which of the following is an inverse agonist

a) Cetirizine
b) Flumazenil
c) Fluvoxamine
d) Ranitidine

 Which of the following is an example of Hit

and Run drug?

a) Clonidine
b) Imipramine
c) Selegiline
d) Haloperidol

Grapefruit juice inhibits

a) CYP2E1
b) CYP3A4
c) CYP2C19
d) CYP2D6

 Hemodialysis is useful in poisoning with all

of the following drugs except?
a) Barbiturates
b) Methanol
c) Salicylate
d) Digoxin

Audience
Orphan drugs are
a) Drugs with high therapeutic failure
b) Drugs with high toxicity
c) Drugs having low therapeutic margin
d) Drugs for rare disease

 Cholinomimetics are useful in all of the

following conditions except?
a) Glaucoma
b) Myasthenia gravis
c) Post operative atony of bladder
d) Partial heart block

 If high dose of Acetylcholine (5 mg) is administered

after atropinization, one would expect ?
a. Increase in Blood pressure
b. Fall in blood pressure
c. No change in Blood pressure
d. None of the above

 All of the following are therapeutic uses of

Prazosin except?
a) Peripheral vascular disease
b) Hypertension
c) Lupus erythematosus
d) Scorpion sting

 Which of the following is not a

cardioselective - blocker?
a) Acebutolol
b) Atenolol
c) Pindolol
d) Metoprolol

Audience
Uses of 2agonists include all of the
following except?
a) To produce sedation in ICU
b) Glaucoma
c) Benign hyperplasia of prostate
d) Hypertension

II Round- Image based questions

& spotters

Identify the plant & mention the active

ingredient obtained from it. Mention 2 C/I for
its use

 Papaver somniferum ---- P album

Morphine -10%
Contraindications
Head injury
Asthma

Identify the image & answer the following

questions

 Consumption of seeds of this plant will lead

to tachycardia, hyperthermia, mydriasis, dry

flushed skin, urinary retention & delirium
a) Mention the active ingredient involved in

above toxidrome
b) Mention the antidote for the same?

Identify the image and answer the following

question

 Mention the plant name along with

substances obtained from it?
What is the current status of this drug

Identify & mention 2 alkaloids obtained

from it with their uses

 Catharanthus roseus (Vinca rosea)

Madagascar periwinkle plant
Uses:
Hodgkin's disease
Acute leukemia

Audience

Identify the ADR

Mention the drugs

producing this ADR

Acute dystonia

i.

Enumerate
few drugs
which
produce this
type of
reaction

ii. Mention the

treatment for

Steps in biosynthesis of Androgens & Estrogen

 Identify the drug A

Mention 2 uses & A/E

 Identify drug A
Mention 2 uses and 2 contraindications

Audience

III- Rapid fire round

Group I
a. Drug of choice for acute PSVT
b. Drug of choice for MRSA
c. Antidote for Paracetamol poisoning
d. Montelukast is an agonist at cys-LT1receptors (T/F)
e. Longest acting insulin is ------------f. Rituximab targets- -------- B-Cell antigen

Group II
a. Drug of choice for Narcolepsy
b. Drug of choice for hypertension in pregnancy
c. Antidote for heparin overdose
d. Sulfonylureas are the preferred drugs in obese
diabetic individuals (T/F)
e. Most commonly used drug for surgical prophylaxis
f. Cisplatin induced vomiting

Group III
a. Drug of choice for status epilepticus
b. D.O.C for digoxin induced ventricular arrhythmias
c. Antidote for Carbamate poisoning
d. Fatty food increases absorption of Griseofulvin (T/F)
e. Drug used to prevent hemorrhagic cystitis due to
Ifosfamide
f. Bacteriostatic first line anti-TB drug

Group IV
a. Drug of choice for OCD
b. D.O.C for the treatment of type II Lepra reaction
c. Antidote for -blocker poisoning
d. Ascorbic acid decreases absorption of iron (T/F)
e. Infliximab is chimeric MAB against -------f. Post exposure prophylaxis for HIV is given for
---------

IV- Buzzer round

 Atropine does not block muscarinic effects

of?
a. Methacholine
b. Carbachol
c. Acetylcholine
d. Bethanechol

 All are true about Mifepristone except?

a. It is progesterone-receptor modulator
b. It does not compete with glucocorticoid for

binding to its receptor

c. In early pregnancy it causes decidual

breakdown
d. It exerts antiandrogenic actions

 Hepatic cholesterol synthesis is maximal between

midnight and 2:00 A.M, hence all of the following

statins to be taken in the evening except?
a. Simvastatin
b. Lovastatin
c. Rosuvastatin
d. Pravastatin

 All of the following are antianginal drugs

except?
a. Ranolazine
b. Nicorandil
c. Disopyramide
d. Allopurinol

 Which of the following toxicities is unique to

voriconazole among all the azole antifungals?
a. Elevation of liver enzymes
b. Visual disturbances
c. Rash
d. Vomiting

Ecstasy (Rave drug) is?

a. MDMA
b.Ketamine
c.Flunitrazepam
d.Cocaine

 High hepatic extraction ratio is seen in all

except?
a. Lidocaine
b. Morphine
c. Verapamil
d. Theophylline