PREPARATIONS 11-15

PREPARATION NO.11
Zinc Oxide Paste
Synonym: Lassars Plain Zinc Paste
Latin Name: Zinci Oxidum
Use of Preparation: Skin Protectant
INGREDIEN QUANTITY PHYSICAL USE IN
TS DESCRIPTI FORMULA
ON
Zinc Oxide 12.5g Molar mass: 81.408 Active
g/mol Pharmaceutical
Melting Point: Ingredient
1,975C
Density: 5.16 g/cm3
Boiling Point:
2,360C
Starch 12.5 White powder Inert Diluent
Density: 1.5 g/cm3
Solubility in water:
insoluble
White Petrolatum, 50g Boiling Point: 302C Ointment Base
qs. ad. Melting Point: 36-
60C
Density: 0.9 g/cm3
 Specialized Equipment: None
Method of Preparation:
Incorporation
Appropriate Container: Tightly
Close container
Recommended Storage Condition:
Store at controlled room
temperature
QUESTION AND ANSWER:
1. How pastes different from
ointments:
Pastes are stiffer than ointments
since they contain larger
proportion of solid materials.
2. What is the method of
administering pastes?
Pastes are intended for
application to the skin( topical
application). They are for external
use only.
3. What is the official paste in the
market?
The official paste in the market is
the Zinc Oxide Paste or also called as
Lassars Plain Zinc Paste which is
prepared by mixing 25% each of zinc
oxide, and starch with white
petrolatum.
 PREPARATION NO.12
Zinc Gelatin
Synonym: Unnas Paste
Latin Name: Gelatinum Zinci
Use of Preparation: Skin
Protectant
 INGREDIE QUANTITY PHYSICAL USE IN
NTS DESCRIPTI FORMULA
ON
Zinc Oxide 33g Molar mass: 81.408 Active Pharmaceutical
g/mol Ingredient
Melting Point: 1,975C
Density: 5.16 g/cm3
Boiling Point: 2,360C
Gelatin 50g White to tan powder; Stiffening Agent
soluble in glycerol
and acetic acid; has
density of 1.3-1.4
Glycerin 112mL Viscous, colorless, and Stabilizer
has a slightly sweet
taste
Molecular weight:
150mL
Purified wate, qs. ad 92.094 Vehicle

Clear, odourless and

tasteless liquid with a
BP of 100deg.C And
 Specialized Equipment: None
Method of Preparation: Fusion
Method
Appropriate Container: Tightly
Close container
Recommended Storage Condition:
Store at controlled room
temperature
QUESTION AND ANSWER:
1. What is gycerogelatin? What
are the compositions of the
preparation?
. Glycerogelatins are plastic
masses containing
gelatin( 15%),
glycerin(40%),water(35%) and
2. How are glycerogelatins applied or
administered?
Glycerogelatin are applied to the skin
for long term. They are melted before
application, cooled slightly above
body temperature, and applied to the
affected areas with a fine brush.
Following application, the
glycerogelatin hardens, is usually
covered with a bandage and is
3. How is Zinc Gelatin used?
.Zinc Gelatin is used in the
treatment of varicose ulcers. This
is melted first before application,
cooled and then applied to the
affected areas with a fine brush.
 PREPARATION NO.13
Glycerin Suppositories
Synonym: Suppository Glycerin
Latin Name: Suppositoria
Glycerini
Use of Preparation: Laxative
 INGREDIE QUANTITY PHYSICAL USE IN
NTS DESCRIPTI FORMULA
ON
Glycerin 8g Molecular Weight: Active Pharmaceutical
92.09 g/mol Ingredient
Mp: 18.17 deg.C
Bp: 290 deg.C

Monohydrate 2g Molecular weight: Alkalinizing Agent

Sodium Carbonate 105. 988 g/mol
Density:2.54 g/cm3
MP: 851 deg. C
Stearic Acid 8g White, solid, pungent Solidifying Agent
Density: 0.9408 g/cm3
MP: 69.3 deg.C
Clear, odourless and
Purified wate, qs. ad 2mL tasteless liquid with a Vehicle
BP of 100deg.C And
MP of 0 deg.C
 Specialized Equipment: None
Method of Preparation: Molding
Appropriate Container: Tightly
Close container
Recommended Storage Condition:
Store at controlled room
temperature
QUESTION AND ANSWER:

1.What are the different kind of suppositories?

Give a brief description of each.
.Rectal Suppositories- these are
suppositories administered rectally.
.Urethral Suppositories- these are intended
for urethral administration.
.Vaginal Suppositories- these are meant for
introduction in the vagina.
QUESTION AND ANSWER:

2.What are the vehicles of

suppositories?
A. Oleaginous Suppository Base
B. Hydrophilic Suppository Base
C. Surfactant Suppository
Base
3. How do you administer suppositories?
.Suppositories are commonly
employed rectally, vaginally, and
occasionally urethrally. Since they
have different size and shape, it must
be even with the intended with the
body orifices.
 PREPARATION NO.14
Orange Water
Synonym: Orange Oil
Latin Name: Citrus
Aurantium Var. dulcis
Use of Preparation:
Carminative
INGREDIENTS QUANTITY PHYSICAL USE IN THE
DESCRIPTION FORMULA

Orange Oil 5 mL Yellow to orange color. Active Pharmaceutical

It has sweet, fresh, Ingredient
and tangy smell.

Ethanol 150 mL Colorless liquid with a Preservative

pleasant smell.

Purified talc 12.5g Odorless, white to Clarifying agent

grayish white, very
fine crystalline
powder.

Purified Water, qs. ad 250 ml Clear odourless liquid Vehicle

Specialized Equipment: None
Method of Preparation:
Alternate method
Appropriate Container: Tightly
Close, light resistant
container
Recommended Storage
QUESTION AND ANSWER
1. Why are the aromatic waters also
known as medicated waters?
.Aromatic water is also called
medicated water defined in the USP
as clear, saturated aqueous
solutions of volatile oils or other
aromatic or volatile substances.
Their odors and tastes are the same
2. What is the difficulty of
experiencing compounding
prescription containing aromatic
waters?
.Incompatibity- the difficulty
encountered in the compounding
of prescription containing
aromatic water is due to a salting
out action of certain ingredients.
3. Give at least 3 examples of
volatile oil that can be used in the
preparation of aromatic waters.
.Cinnamon Oil
.Peppermint Oil
.Rose Oil
 PREPARATION
NO.15
PEPPERMINT
Synonym: WATER
Aqua mint,
American mint
Latin Name: Aqua Menthes
Peppermint
Use of Preparation:
INGREDIENTS QUANTITY PHYSICAL USE IN THE
DESCRIPTION FORMULA

Peppermint Oil 5 mL Colorless to pale Active

yellow greenish Pharmaceutical
liquid. Ingredient
It has strong
peppermint odor.

Ethanol 150 mL Colorless liquid with Preservative

a pleasant smell.

Purified talc 12.5g Odorless, white to Clarifying agent

grayish white, very
fine crystalline
powder.

Purified Water, qs. ad 250 ml Clear odourless liquid Vehicle

Specialized Equipment:
None
Method of Preparation:
Alternate method
Appropriate Container:
Tightly Close, light
resistant container
Recommended Storage
QUESTION AND ANSWER
1. What are the different
processes/methods used in preparing
aromatic waters?
A. distillation
B. solution method
-direct solution
C. alternate method
2. What is cohobation?
Cohobation is the process of
redistillation of the same water,
with the liquid drawn from it.
3. What is the importance of purified
talc in the preparation?
Purified talc is used in the preparation
of aromatic waters in order to adsorb
the existed droplets of organic
compounds during its preparation.