KHAIRUDDIN DJAWAD

Chronic disease
Pilosebaceous unit
Location: central face
Capillary hyperactivity
 Age : 30 50 years old
peak age: 40 50 years old
Sex : Female : male = 3 : 1
but men are prone to rhinophyma more
than women
Race : Caucasian and Northern
Mediterranian
 Heat

Helicobacter pylori

Demodex folliculorum Vascular Hyperactivity

Propionibacterium acnes

Menopause

Parkinson Disease

Drugs
 Vascular Hormones Food
Hyperactivity
Demodex
Sun Exposure folliculorum

Vascular Instability Vasoactive

Tissue Damage Substances

Cytokine Release Emotional

Stress

Inflammation

Immunitary
System Activation
 Granulomatous Rosace

Rosacea Conglobata

Rosacea Fulminans
 Bacterial Culture

Skin Biopsy
 Erythematelangiotatic: superficial perivascular
lymphohistiocytic infiltrate and telangecsia.
Papulopustular: chronic nonspecific infiltrate,
usually on perifollicular area.
Phymatous: increased quantity and size of
sebaceous glands, dilatation of pilosebaceous
ducts and keratin plugs.
Demodex folliculorum sometimes can be found.
 Acne
SLE Vulgaris
Systemic Drugs Erythematelangiectatic

Topical Drugs Papulopustular

Invasive Phymatous
Therapy

Others
 Tetracycline HCl, oxytetracycline,
doxycycline, minocycline
Erythromycin
Metronidazole
Isotretinoin
H. Pylori eradication therapy
 Metronidazole
Azelaic Acid
10% sodium sulfotenamide / 5% sulphur
Erythromycin
Tretinoin
D. folliculorum eradication therapy
 Surgery

Laser Therapy

Ablative Therapy
Avoid Inducement Factors
Facial Massage
Other
 Disfigurement may cause loss of
confidence in the patient and inhibit their
social function.
 It is a controllable
disease.
What is needed:
DEDICATION by the
physician and the
patient for the
resolution of the
disease.