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By
Dr. Khaled
Khalil
By the end of this session, the student
should be able to:
o Outline the various factors affecting airway resistance and
correlate it to changes in pulmonary ventilation.
o Describe the metabolism of surfactant, discuss its
significance and relate its deficiency to clinical conditions.
- Because of the high surface tension, plasma fluid leaks into the
membrane disease".
- RDS babies can be saved by mechanical ventilators that keep
lung compliance)
Factors affecting compliance:
- It is affected by elastic forces of the lung (1/3 of compliance) and surface tension
of the fluid lining the alveoli (2/3 of the compliance).
- Lung compliance is decreased in pulmonary congestion, pulmonary fibrosis and
pulmonary edema whereas it is increased in emphysema.