FISIKA PARU

Avogadros law and number

Equal volumes of gas at the same pressure
contain the same number of molecules.
6.02 x 10 23
Concentration of gas - Gas pressure
Boyles law of gas
V~P
Pressure varies inversely with volume
Volume varies inversely with pressure
mm Hg -- cm H2O -- Torr
 Daltons Law of Partial Pressure
 Fickes Law of Diffusion
Grahams Law
Diffusion of gases varies with molecular
weight
higher molecular weight the slower the
diffusion
Oxygen diffusion = pure gas
Carbon Dioxide diffusion = CO2 and
Bicarbonate Ions
Henrys Law - law of the coke bottle
The amount of gas dissolved in a liquid varies
directly with the total quantity of gas and the
pressure of the gas.
 Charless Law - effects of temperature on
a gas
Pressure varies with Temperature
Heating a can example
Interaction with Boyles law
Daltons Law of Partial Pressure
Partial Pressure of a gas is proportional to the
proportion of that gas in a mixture of gases
Oxygen 21% of 760 Torr = 160 Torr
Nitrogen 79% or 600 Torr
 Key Gas Laws Reviewed
Solubility of a gas depends on:
Partial pressure of that gas (example: O2 =156 mmHg)
Temperature
Solubility in a particular solvent
Water: solvent for life
O2 into water: 0.1 m moles/L (poor)

CO2 into water: 3.0 m mole/L (good)

PARTIAL PRESSURE OF THE GAS

Gas Atm airway Alveoli exp

N2 597.0 563.4 569.0 566.0

O2 159.0 149.4 100.0 120.0

CO2 0.2 0.2 40.0 27.0

H2O 3.8 47.0 47.0 47.0

Total 760.0 760.0 760.0 760.0

 Diffusion and transport
exp
insp
PO2 149 PO2 116
RR PCO2 26
PCO2 0.2

PO2 100
PCO2 40
artery
venous
^PO2 60
^PCO2 6 PO2 95
PO2 40
PCO2 40
PCO2 46

^PO2 >55
^PCO2 > 6
PO2< 40
PCO2>46
tissue
 Kecepatan difusi

Ficks Law
. L. perm koef .difusi
Vgas P
tebal jaringan
Luas permukaan : luas alveoli & kapiler
Koefisien difusi : CO2 20 x O2
Tebal jaringan : membran respirasi
Beda tekanan : antara kedua tempat
CO2 < O2
Kecepatan difusi O2 dan CO2 hampir sama
Surface Tension
Figure 17-11b: Surfactant reduces surface tension
 Basic Mechanical Model

Spring
Fapp Mass
R (oil)
Basic Mechanical Model

Fopp
Spring
Fapp Mass
R (oil)
 Equation of Motion
Newtons Law

Fapp = Fopp

Fopp = Fel + F res + Fin

Elastance
Resistance
Inertance
Model of Lung Inflation: Statics