Intergovernmental Forum on Chemical Safety (IFCS) VI

September. 15-19, Dakar, Senegal

|

(nierchoi@me.go.kr)





 



Characteristic physico- Difficult application of

chemical properties of nanomaterials commercial analysis

Undefined risk of Increased exposure-frequency

manufactured nanomaterials of nanomaterials

Complex risk-prediction due to

International issue
manufacturing (e.g. surface modifications)



 #"
!
"



Inhalation
§ Ambient air,
Úanufacturing, Workplace exposure
Landfills,
Wastewater effluent Ingestion
Food, Drinking water,
§ Incidental
Wear/Attrition of tires, Dermal
Sunscreen, Brake pads, etc; Sunscreen, Cosmetics
Storm water run-off;
Wet deposition

Accumulation
Uptake Release
Air filtration
Photolysis 

Coagulation and
UV
Sedimentation



Aggregation Sand filtration
Biotransformation

   !
   
$


|orea government is promoting the research of nanotechnology based on Ɲ|orea
National Nanotechnology Development Planƞ. At present, it is in Ɲthe 2nd |orea
National Nanotechnology Development Plan (2006~2010)ƞ.

In the 2nd |orea National Nanotechnology Development Plan, 4.8 mil. USD was
invested from government and private corporations for the vision of Ɲdeveloping
competitive power of nanotechnology for the technical big country.

The many ministries have been participated in the research of nanotechnology.

The Úinistry of Education, Science and Technology (ÚEST) generalizes the
research of nanotechnology at the governmental levels.

By describing clearly as ƠAfter the head of the related ministries build the policy
about nanotechnology in order to enhance the effectiveness of the policy
promotion, it should be notified to the minister of the ÚEST (Nanotechnology
Promotion Law, Clause 4, Art. 2)ơ, the national nanotechnology development
policies have been promoted through the ÚEST to enhance effectiveness



    

The 2nd National Nanotechnology Development Plan

- Analysis of social and economic effects of nanotechnology


%
- Research about health, safety, environment, and ecosystem of
&
nanotechnology

- Establishment of DB and information service
- Úutual cooperation and connection to Úinistry of Environment (NIER),
§
|orea Food & Drug Administration (|FDA), |orean Agency for
" '!
Technology and Standards(|ATS), and |orea Research Institute of


Standards and Science (|RISS).
- Survey on the existing laws relating to the effects such as health,
safety, environment, and ecosystem of nanotechnology.
The review about need for future legal and regulatory

!
- Supporting the monitoring research for the environment surveillance
( 
system of nanomaterials release.
- Research and preparing procedures for detecting the pollution source
of nano-products and nanomaterials
Ú

 


  !



  
!§&
 $


ü In the National Institute of Toxicological Research (NITR) under the |
, total 5.5
mil. USD will be invested to Ɲthe fundamental project about the toxicity of
nanomaterialsƞ from 2007 to 2011 (1 mil. USD in 2007).

ü In the |orea Institute of Environmental Science and Technology (|IEST) under the
Úinistry of Environment (Ú
), total 1.5 mil. USD will be invested to ƝEco-technopia
21 Projectƞ from 2007 to 2010.

ü In the |orea Science and Engineering Foundation (| SEF) under the Ú
, the
research expenses of total 5 mil. USD, 1.5 mil. USD per year, will be invested to
Ɲthree detail projects of creative research initiatives in the nanotechnology
development projectƞ from 2008 to 2010.

ü The chemical management division under the Ú E is drawing up the 5-year

roadmap for safe management of nanomaterials. The environmental health policy
division is promoting the detail industrialization process of the large research field,
Ɲdevelopment of safe management for new environmental risky factorsƞ in the fusion
environmental technology development project.


 §)*
!+
 ,-

Current EHS projects (completed/on-going) about nanomaterials

Researcher Subject title Sector Subsector Year
Environmental toxicity analysis and risk assessment of Si 2 Safety
|orea Research Foundation Risk 2006
and Ce2
nanopowder assessment
system/educa
|orea ccupational Safety & Nanomaterial hazardous assessment and prevention strategy
EHS tion/public 2007
Health Agency of occupational health effect
relations
|orea Institute of Assessment of environmental exposure and effects and
Safety
Environmental Science and management technology of nanomaterials assessment and Risk 2007
assessment
Technology management
National Institute of Database inventory for risk assessment of nanomaterials and Safety
Risk 2007
Environmental Research methodological research of risk assessment assessment
Investigation of nanomaterials distribution (transfer and
Úinistry of Environment Risk Úanagement 2008
mitigation) and introduction strategy of survey system.
Personal protection equipment for safety assessment of Safety
|orea Research Foundation Risk 2008
nanomaterials and penetration research on artificial skin assessment
|orea Science and Creative research of basic science program about Safety
Risk 2008
Engineering Foundation nanomaterials) ƛ project no. 5, 6, & 7 (7/25) assessment



$



$ 
$  |(#
.* (|orean Agency
for Technology and
$  Standard)
!
(National Institute of
Environmental Research)

/#0
 $ 

 
+
(National Institute of  
Toxicological Research) (|orea Research Institute
of Standard & Science)
 X 1  , -

  


       
 +  
 
 
 +
   

       
 







!   
 "  "             |      
     
   
     
 



  "   

  % 
3 

   
,4556-        
     0 ( 



   

" 
  (

  



 
   %   



  
   

    
 
. 
   

 
0      
"


 
   '
  9  : 

0 !      *    ! 

 
 
.       "   
4 
,4557-






  %  
 
 *  
"
 

   *


  .
  
     

 






     
;


<
 ! 






!2  

 )
  
 

  
     "
 
" 
 
  
   
  
X  

!    '


     




,4558- &    



       

  
   
    

    ! 
     "    
    
 _
 
 
  
 

 


 




  
 


  


  

 

 

 

 



  
 

 
 

 
    


  
 
  
 


 

 
  


  






 0!'!
=.
þ
   

  

  þ 
 
0! 
 
! 
 

  



  
 
  



  


  


§ 

% 

*  
0'>

Supporting international cooperation of

Supporting decision making
ministry of environment
ë
 


  


  




 "



  



 




 
 





 


ë  
ë
  ]

 ]
]ë
  







 

|



 "
§
|

Frying pan Refrigerator Filter of water purifier Toothpaste

(Zr 2 coating) (AgNP) (AgNP) (AgNP)
Nano lab Samsung, LG Hankook bionano-tech NPC

Lexon: conductivity coating sol

Nanochemical: Photocatalyst
Carbon nonotec: CNT, Nanofilter
ABC nanotec: Antibiotic AgNP
Nanomirea: Carbon nanofiber

32

 â 
42 (â ?
+


 !%

""#Ú$ %# %# $&# #

ü _%'
ü ' #"#""# ()%
ü *'##_ +###

# #""#' ," Ú-  &

ü $%+*%- #+ #$%#
ü "#( &
( -
ü $#%## .$##/+
##"%

0'+# #"'
$ _##
ü Ú_##

 # '###



 !
" *9 :
## #
_ 
'$##"#
Ú#"'_#

 2 2!$2

%'# %##

 ##

###" & 2_'

&% #&
 ! #
 7' # 9#Ú-
 _ #

#'# $ $

) )
34
#+3
4
 '#% #-
 #%
354*#+364
Ú # #
' #
 /" ##
 !%&1&&#
$/00*2 $
*
 ,%#%

!#_##
 Ú ,

0$!7
802




ECD Activities

°  
 

! "


# 

ë 

$ % 


 





!

ECD WPÚN : 8 Steering group

Exposure Úeasurements & Exposure
ECD Database on EHS Úitigation
Research Alternative methods
in Nano Toxicology

EHS Research Cooperation on

Strategies on ÚN 0 Risk Assessment

Safety Testing of a Cooperation on

Representative of ÚN Voluntary Schemes &
ÚN & Test Guidelines regulatory Programs



 § 0!
â WPÚN (Working Party on Úanufactured Nanomaterial) (
rd Úeeting, Nov. 2007) decided
to organize SG7 and SG8.
â |orea is working for SG1, SG
, SG4, and SG8 as a participant.

3
00*

,
-
@ 7
 "

4 ?
  $

   
  "
$
$

 §,- ,B-

, -

C D A 6

   $

  !$
!  &  "
$


 
 ,B|- ,B|-
,B-+,- ,B-+,-

3 4 C D

§
 
  

 þ 
 
§ 

  
 ÷  
å 

 &'ë()

*& ë"+,!!-( ë.&'ë( r %
 &'(


 §
 ,C-


E 



*FG& 
2

/
 3-/
,A5-

*
* 2) Single-walled carbon nanotube (SWCNTs)

C-$
(*
*,$ -
 D-!,
5) Iron nanoparticles,
6) carbon black
" 6- 
"
8) Aluminum oxide
9) Cerium oxide,
10) Zinc oxide
33-"
§  12) polystyrene
0
1
) dendrimers

14) Nanoclays

â 5 types of fullerene (C60), ÚWCNT, Silver nanoparticles, Ti 2, Si 2 since 2007

(Eco-Technopia-21 project, Úinistry of Environment).


 §
 ,D-
!("  D
( * 
H

"2
>  
  

> 




> 

>  

> 
 
> . 
> % +

> /

> ÷

 
 
     



> ! 
> §

> 
>  

   
>   
>    

> Ä
 + 


> ´  

â |ey metrics (bold letter) and researched nanotoxicity since 2007 (Eco-Technopia-21 project, Úinistry
of Environment)


 ß Phase 1 (ƞ08-ƞ10)
- Data gathering
- Research Project : F" G
ß Interim Assessment : WPÚN 8 (ƞ11)
ß Phase 2
- Based on the result of the phase 1
- Decide additional endpoints/material to investigate
- develop data for decision support: F 
 G



 ü How to share test materials

ü How to account for testing already done on

sponsored materials and endpoints

..++(((% + +:%



 $ .,- ,- *

/
,A5- I+ B J
 + + B+
  I+ B
/+ J
 + + B+
$  I+ B |+ >

/+ J
 + + 
+ B
! B+ |

J /+ J

 J + B
 + B
**&

|+ + +


"  /+ J
>
+ B


"  + B

" B|'>
,
-+ B  
+  + B
K" B|'>
,
- 
J+ >
,/
- 
+ 
" BJ |+ >
,/
- B+ /
§   |
0  B
  B



ü Cooperation & coodination with relevant stakeholders : 0+

 & national activities
' Completed/ n-going/Planned : Úanufactured nanomaterials/technology,
Environment and health safety
$Report research status to ECD secretariat for information sharing
- Testing for ECD test guideline application
(Target : Úolecular, Cellular, Cultural level of biota)

ü ECD Workshop on the Safety Testing of Úanufactured

Nanomaterials (19-21 November 2008, Busan, |orea)
DDP for Sponsorship Program : SG
, SG4, SG7


ECD |orea Workshop (Nov. 19-21, 2008, Busan)
Development of DDP for Sponsorship Program : SG
, SG4, SG7 (alternatives)
* Symposium on EHS of Nanomaterials (Nov. 18, 2008, Busan)



§