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R= h t3
Synthetic hormones:
Mechanism of action
It inhibits thyroperoxidase & prevent oxidizing
anion iodide (I) to iodine (I2), hypoiodous acid
(HOI), enzyme linked hypoiodate (EOI) facilitating
iodine's addition to tyrosine residues on the
hormone precursor thyroglobulin, a necessary step
in the synthesis of triiodothyronine (T3) and
thyroxine (T4).