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THE PROFESSIONAL
CHOICE
A d v a n c e d C o s m e c e u t ic a ls
Lightenex Max Peel
Depigmentation peeling mask
with
Reduce the activity of abnormal melanocytes, which cause Melasma & post
Works by replacing the melanin carrying-keratinocytes with new cells from the Dermal-
Epidermal junction (inside-out) instead of conventional acid peels which cause outside-in
exfoliation.
Extensively tested in the UK
Suitable for all skin types, including Skin type 4-5, as there is no necrosis (which can result
in hyperpigmentation or scarring).
Maintain at pH 2.2 using Mandelic acid, which makes it acidic without the irritation of
Glycolic acid in dar skin.
Lightenex Max Peel works by eliminating the melanin patches on the face caused by melasma, chloasma,
sun damaged age spots, acne & post-inflammatory hyper-pigmentation (PIH).
INGREDIENTS
DEPIGMENTERS in pH 2.2
MANDELIC ACID 20%
AZELAIC ACID 10%
ALPHA-ARBUTIN 5%
DIOIC ACID 5%
ASCORBIC ACID 10%
PHYTIC ACID 5%
FERRULIC ACID & MIXED TOCOPHEROLS
NIACINAMIDE 5%
KOJIC ACID 5%
SALICYLIC ACID 2%
EXFOLIANT:
RETINOL 7% (ENCAPSULATED)
MANDELIC ACID
Much larger molecule than Glycolic & penetrates the skin slowly & more evenly without
irritation & hot spots.
Safe in dark skins (unlike TCA & Glycolic acid it can be safely left on skin for 8-10 hours)
DEPIGMENTERS EXFOLIANTS
Proven Synergy
Kojic acid Glycolic Acid
Alpha arbutin y
(In Pre peel)
rg
en Syne
v
Azelaic acid Pro Retinol
y
erg
Syn Mandelic Acid
Phytic acid Pro
v en
DOCUMENTED SYNERGY
39 patient split face study comparing
Kojic Acid 2% & Glycolic Acid 5% with
Hydroquinone 2% & GA 5%
showed better results with Kojic Acid.
Retinol is the chosen exfoliant because it has been shown to penetrate skin more
effectively than Retinoic acid or Retinyl Palmitate to give the
best inside-out peeling possible.
This avoids the inflammation or necrosis involved with high strength AHAs.
REF-Unoccluded Retinol penetrates Human skin in vivo more effectively than unoccluded Retinoic acid or Retinyl palmitate.Journal of
Investigative Dermatology(1997)109,301-305;doi:10.1111/1523-1747.ep12335788.Dept of Dermatology ,University of Michigan Med
School,Ann Arbor,Michigan,USA.Elizabeth A Diell et al.
Azelaic acid A d v a n c e d C o s m e c e u t ic a ls
REF 1-Pharm Bull.2004 April;27(4):510-4.Inhibitory effects of alpha-arbutin on melanin synthesis in cultured human
melanoma cells and a three-dimansional human skin model.Sugimoto K,Nishimura T,Nomura K,Kuriki T.Biochemical
Research Laboratory,Ezaki Glico Co Ltd.,4-6-5 Utajima,Nishiyadogawa-ku,Osaka 555-8502,Japan.
Dioic Acid
(Octadecene-dioc Acid) 5% A d v a n c e d C o s m e c e u t ic a ls
This acid is a Di-carboxylic acid (dioic) like Azelaic but is 18 Carbon atoms long instead of 9 carbons like Azelaic.
It is made from Bio-fermentation of Oleic acid using Yeasts.
REF 5-Inter Jour of Cosmetic Science,Volume 33,issue 3 June,pages 210-221.J M Gillbro,M J Olsson.The Melanogenesis&mechanisms of
skin lightening agents,existing &new approaches.
Ascorbic Acid 10% A d v a n c e d C o s m e c e u t ic a ls
Ref: A double blind randomized trial of 5% ascorbic acid vs. 4% hydroquinone in melasma | International Journal of
Dermatology | Volume 43, Issue 8, pages 604-607, Aug 2004 | Liliana Elizabeth Espinal Perez MD et al.
Ferulic Acid &
Vitamin E synergy A d v a n c e d C o s m e c e u t ic a ls
Ref-12-The depigmenting effect of tocopheryl ferulate on human melanoma cells. Br J Dermatol.1999 Jul;141(1)141(1):20-9.
Phytic Acid 5% A d v a n c e d C o s m e c e u t ic a ls
makes Melanin.
Gentle exfoliant
REF-Will Phytic acid replace Hydroquinone. Romulo Mene MD. Plastic Surgeon.Rio De Janiero,Brazil. Third Congress of
National Estetic Medicine.Milan,Italy 12 Oct 2001
Phytic Acid 5% A d v a n c e d C o s m e c e u t ic a ls
A double blind, vehicle controlled trial in 30 healthy subjects with greater than 2
Solar Lentigines were randomly signed to apply
Ascorbic Acid 10% + Phytic Acid 2%
over 3 months showed statistically significant improvement between study drug
& vehicle.
Ref: Journal of Cosmetic Dermatology | volume 10, issue 4, pages 266-272, Dec 2011 | Randomozed controlled study to evaluate
the depigmenting activity of L-Ascorbic acid plus Phytic Acid | Abdullah Khemis MD et al.
Patient Choice A d v a n c e d C o s m e c e u t ic a ls
wrinkles.
Photo damaged skin.
Method of Application A d v a n c e d C o s m e c e u t ic a ls
IN CLINIC:
The patient washes off the mask using gentle soap & water.
Pat dry the skin using a fresh, clean towel to leave the skin slightly moist.
Massage Moisturix spf 25 every two hours.
Must use Sun Blockex spf 50 if they are to leave home during day time.
(The skin will be red & tight for 48 hours & then flaking of skin will commence.
This flaking continues for another 3 to 5 days.)
The patient sees the Clinician on day 7 when the decision for touch up is made.
The touch up is again applied after degreasing with acetone & left on for four hours
before washing off.
Apply Lightenex Plus cream (maintenance) three times daily after day 4.
(Some patients will see blemishes appearing & disappearing during the first 7-10
days. This is because the Melanified dead keratin tend to bunch together before
shedding)
Lightenex Max Peel
Depigmentation peeling mask
IT IS ESSENTIAL
Conclusion
Lightenex Max
Depigmentation peeling mask
Works
Pharmaclinix.com