Patologia glandelor endocrine.

Endocrine glands pathology.

 Tema. Patologia glandelor endocrine.
I. Micropreparate:
132. Gu coloid. (coloraie H-E). Indicaii:
1. Foliculi mrii n dimensiuni, dilatai.
2. Mase coloide n lumenul foliculilor.

115. Gu tireotoxic (basedovian) (coloraie H-E). Indicaii:

1. Foliculi deformai.
2. Proliferarea epiteliului folicular cu formarea unor structuri papilare.
3. Coloraia slab i vacuolizarea coloidului.
4. Infiltraia limfocitar a stromei.

210. Adenom hipofizar bazofil. (coloraie H-E). Indicaii:

1. Celule tumorale cu citoplasma bazofil.
2. Hemoragii n stroma tumorii.

224. Glomeruloscleroz diabetic nodular. (coloraie H-E). Indicaii:

1. Focare de scleroz i hialinoz a glomerulului renal.
2. Glomerul nemodificat.
3. Tubi contori.

II. Macropreparate
132. Gua difuz
133. Adenom de suprarenal
: .
I. :
132. . ( -). :
1. .
2. .

115. . ( -). :
1. .
2. .
3. .
4. .
5. - .

210. () . ( -). :
1. .
2. .

224. [ ]. ( -).
:
1. , ..
2. .

II. :
132.
133.
 Endocrine glands pathology.
icrospecimens:
32. Colloid goiter (H.E. stain). Indications:
licles are dilated and increased in size .
sses of colloid in the lumen of the follicles.

15. Toxic diffuse goiter - Graves disease (H.E. stain). Indications:

storted follicle.
oliferation of follicular epithelium with formation of papillary structures.
eakly stained colloid with vacuolisation.
mphocytic infiltration of the stroma.

10. Chromophob adenoma of hypophisis (H.E. stain). Indications:

moral cells with basophilic cytoplasm.
morrhages in the tumor stroma.

24. Diabetic (nodular) glomerulosclerosis (H.E. stain). Indications:

ci of sclerosis and hyalinosis of renal glomerulus.
changed glomerulus.
nvoluted tubes.

Macrospecimens
32. Diffuse goiter.
33. Adrenal gland cortex adenoma.
Gu coloid
 1

132. Gu coloid (coloraie H-E)

Gu tireotoxic
2 1

115. Gu tireotoxic. (coloraie H-E

 Gu autoimun
(Hashimoto).

macro atrofia glandei

tiroide.
Adenom tiroidian folicular
Carcinom de tiroid
papilar i medular
Osteodistrofie
paratiroidian,
adenom paratiroidian.
Hipofiza,
micro: stnga neurohipofiza,
dreapta adenohipofiza, celule
bazo- i acidofile
 Gigantism,
(adenom eozinofil
hipofizar)
 Sindrom Cushing
(adenom de suprarenal i adenom bazofil hipofizar)
Adenom hipofizar bazofil
 1

210. Adenom hipofizar bazofil (coloraie H-E)

 Atrofia suprarenalelor n boala Addison,
Suprarenale normale,
Adenom de suprarenale n sindromul Cushing
Tuberculoza (necroz cazeoas) i
amiloidoza (rou de Congo) a
suprarenalelor.

Clinic boala Addison.

 Adenom de suprarenal

(sindromul Cushing corticosterom,

sindromul Conn - aldosterom).
 Feocromocitom

macro, micro, microscopia

electronic granule
catecolaminice
 Insul Langherhans
normal;

Insulit autoimun, diabet

tip I;

Amiloidoza insulei
pancreatice,
diabet tip II
 2

1
3

224. Glomeruloscleroz diabetic nodular (coloraie H-E)

Insulom pancreatic,
sus dreapta reacie
imuohistochimic
la insulin (insulom )