Samuel C.

Brillo

Mitosis
Lets review! Series of events that take place in cell

The Cell Cycle

which leads to division and duplication of
DNA to produce two daughter cells.

Phase Activity Time Some cells that

temporarily or
permanently
G0 phase withdraw from the
G1 phase Cell proliferation 5 hours cell cycle are said to
enter the G0 stage.

S phase DNA synthesis 7 hours

Cell development,
cell enlargement,
G2 phase 3 hours
preparation for
mitosis

M phase Cell division 1 hour

Words to Ponder
DNA carrier of genetic information.
Chromatin coiled DNA/fiber form
Chromosome a coil within a coiled DNA;
condensed DNA visible.
Chromatid building block of chromosome
(half block).
Centromere Central region of
chromosome
Kinetochore Point of attachment of
spindle fiber; protein spikes in centromere
Centrosome - an organelle near the
nucleus of a cell that contains the centrioles
(in animal cells) and from which the spindle
fibers develop in cell division.
M phase
-Also called Mitotic phase converts diploid cell into two diploid
daughter cells.
-Occurs in somatic cells (body cells except gametes)
-Consists of four main phases:
1. Prophase
2. Prometaphase
3. Metaphase
4. Anaphase
5. Telophase
-After telophase, cytokinesis occurs.

REMEMBER! Papa, Please Make A Tea.

Lets study the structure of
Chromosome.
Prophase
Chromosomes condense and
become visible to naked eye under
microscope.
(Remember that chromosomes are
invisible during interphase.)
Spindle fibers emerge from
centrosomes.
Nuclear envelope breaks down
(Remember that nuclear envelope
came from nucleus)
Centrosomes move toward the
opposite poles.
Prometaphase
Chromosomes continue to
condense
Kinetochores appear to
centromeres
Mitotic spindle microtubules
attach to kinetochores.
Metaphase
Chromosomes are lined up,
arranged at the center of cell
called metaphase plate
Each sister chromatid is
attached to a spindle fiber
originating from opposite
poles.
Anaphase
Centromeres will split/cute
into two.
Sister chromatids are pulled
toward to opposite poles.
Spindle fibers will continue to
elongate the cell, which also
contributes to the cell to push
apart.
Telophase
Telophase is the final stage.
Once chromosomes arrive to
opposite poles, chromosomes
will be decondensed.
Each set of chromosomes will
surround by nuclear
envelope.
Mitotic spindle will break
down
Spindle fibers continue to
push poles apart.
 In animal cell:
-A cleavage furrow forms,

Cytokinesis which separate daughter cells.

In plant cell:
-A cell plate forms, which also
precursor of cell wall.
Mitotic stages in Onion cell, Allium sativum
Mitotic stages in Whitefish,
Coregonus clupeaformis
Lets recap!
Lets have a game!

Bring me, Bring me!

Assignment

1. What is meiosis?

2. What are the main

differences between
meiosis and mitosis?

3. Why is meiosis
important?