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Ever dozed through

chemistry class and


wondered what chemistry
had to do with you? A lot!
Your body produces its
own chemicals and uses
them to control certain
functions, and the main
system that coordinates
these chemicals is called
the endocrine system.
What Is the Endocrine System?

It influences almost every


Plays a role in:
cell, organ, and function of
our bodies.

1. Regulating mood
2. Growth and
development
3. Tissue function
4. Metabolism
5. Sexual function and
reproductive
processes.
Are the foundations of the endocrine system

Hormones Glands
The body's chemical Is a group of cells that
messengers produces and secretes,
Transfer information and or gives off, chemicals.
instructions from one set Selects and removes
of cells to another. materials from the blood,
Move through the processes them, and
bloodstream secretes the finished
Each type of hormone is chemical product for use
designed to affect only somewhere in the body.
certain cells. Release their secretions
in specific areas.
The major glands are:
Is a collection of specialized cells. Is the main link between the
endocrine and nervous
systems.

Is located in the lower


central part of the brain.

Nerve cells in the


hypothalamus control
the pituitary gland by
producing chemicals.
Pituitary
Is located at the base of the Is considered the most
brain just beneath the important part of the endocrine
hypothalamus. system.

It's often called the "master gland.

The production and secretion


of pituitary hormones can be
influenced by factors such as
emotions and changes in the
seasons.
The pituitary is divided into two parts:

The anterior The posterior


lobe lobe

Produces hormones
Regulates the
such as:
activity of the
Growth hormone
thyroid, adrenals,
Prolactin
and reproductive
Thyrotrophin
glands.
Corticotrophin:
Releases
antidiuretic
hormone, which
helps control the
balance of water
in the body.
Thyroid

Is located in the front part


of the lower neck.

Produces the thyroid


hormones thyroxine and
triiodothyronine.

Control the rate at


which cells burn fuels
from food to produce Is shaped like a bow
energy. tie or butterfly.
Are four tiny glands that
function together called the
parathyroid.

They release parathyroid


hormone, which regulates the
level of calcium in the blood
with the help of calcitonin,
which is produced in the Attached to
thyroid. the thyroid.
The body also has two triangular adrenal glands, one on top of each
kidney.

The outer part The inner part

The adrenal medulla,


The adrenal cortex, produces
produces
hormones called
catecholamines, such
corticosteroids that influence
as epinephrine. Also
or regulate salt and water
called adrenaline,
balance in the body, the
epinephrine increases
body's response to stress,
blood pressure and
metabolism, the immune
heart rate when the
system, and sexual
body experiences
development and function.
stress.
Pineal
Is located in It secretes melatonin, a hormone that may
the middle of help regulate when you sleep at night and
the brain. when you wake in the morning.
The gonads are the main source of sex hormones.

In guys the male gonads, or testes,


are located in the scrotum. They
secrete hormones called
androgens, the most important of
which is testosterone. These
hormones tell a guy's body when it's
time to make the changes
associated with puberty, like penis
and height growth, deepening
voice, and growth in facial and
pubic hair.
A girl's gonads, the ovaries, are located in her pelvis. They
produce eggs and secrete the female hormones estrogen and
progesterone. Estrogen is involved when a girl begins to go
through puberty. During puberty, a girl will experience breast
growth, will begin to accumulate body fat around the hips and
thighs, and will have a growth spurt. Estrogen and progesterone
are also involved in the regulation of a girl's menstrual cycle.
The pancreas is also part of the body's hormone-secreting
system, even though it is also associated with the digestive
system because it produces and secretes digestive enzymes.

The pancreas produces two important hormones, insulin and


glucagon. They work together to maintain a steady level of
glucose, or sugar, in the blood and to keep the body supplied with
fuel to produce and maintain stores of energy.
What Does the Endocrine System Do?

Once a hormone is secreted, it travels from the


endocrine gland that produced it through the
bloodstream to the cells designed to receive its
message.
The target cells have receptors that latch onto only
specific hormones, and each hormone has its own
receptor, so that each hormone will communicate
only with specific target cells that have receptors for
that hormone. When the hormone reaches its target
cell, it locks onto the cell's specific receptors and
these hormone-receptor combinations transmit
chemical instructions to the inner workings of the
cell.
When hormone levels reach a certain normal amount, the endocrine
system helps the body to keep that level of hormone in the blood.
For example, if the thyroid gland has secreted the right amount of
thyroid hormones into the blood, the pituitary gland senses the
normal levels of thyroid hormone in the bloodstream. Then the
pituitary gland adjusts its release of thyrotropin, the hormone that
stimulates the thyroid gland to produce thyroid hormones.

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