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with MasterPlex QT
This presentation accompanies the free webinar recording at:
https://www1.gotomeeting.com/register/351125992
July 29, 2010
Presenters: Robert Lynde
Deputy Director
Sales Operations & Strategic Alliances Manager
Allen Liu
Supervisor
Technical Support & Project Management
© Hitachi Software Engineering America, Ltd. 2010. All rights reserved.
Topics
1) A close up look at the 4-PL and 5-PL model equations
2) Heteroscedasticity & Weighting
3) BONUS: What’s New in MasterPlex QT 2010
4) Ensuring the quality of your data with the Quality Control
Manager
5) How to use time-saving features such as templates & Best Fit
• F(x) = ((A-D)/(1+((x/C)^B))) + D
• Nonlinear regression
• Monotonic
– e.g. For every MFI, there is only one
concentration
• Symmetrical around the midpoint or
inflection point
D = maximum asymptote
A = minimum asymptote
< low standard OR lowest extrapolated value
© Hitachi America, Ltd. 2010. All rights reserved.
Caution on Extrapolation
• F(x) = A + (D/(1+(X/C)^B)^E)
• Nonlinear regression
• Monotonic
• Key difference = asymmetry
• E = asymmetry factor
• E = 1 = 4PL model equation