• Psoriasis associated with liver disease, that is often found in patients

with NAFLD.
• Psoriasis was higher prevalence mild liver disease, including hepatitis
chronic, alcoholic liver disease, and NAFLD.
Epidemiology
Hepatic disease
• There is associations between psoriasis
• Psoriasis berhubungan dengan penyakit hepar, yaitu sering ditemukan pada pasien
dengan nafld. Selain itu psoriasis juga memiliki prevalensi lebih tinggi pada penyakit hati
'ringan’, termasuk hepatitis kronis, penyakit hati alkoholik, dan NAFLD

• Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease in Western
industrialized countries and encompasses a spectrum of liver disorders from mild hepatic
steatosis to nonalcoholic steatohepatitis (NASH).
• Associations between psoriasis and NAFLD have been reported in the literature.
• In a meta-analysis of 7 observational studies that were considered low to moderate
quality and, for the most part, did not adjust for potential confounding factors, such as
metabolic syndrome, NAFLD was found to be more prevalent among patients with versus
without psoriasis.
Epidemiology
• Beyond NAFLD, a crosssectional study in the United Kingdom found
that psoriasis was associated with a higher prevalence of ‘‘mild’’ liver
disease, including chronic hepatitis, alcoholic liver disease, and NAFLD
• A positive dose-response relationship between psoriasis severity
based on BSA involvement and ‘‘mild’’ liver disease was also seen.