Академический Документы
Профессиональный Документы
Культура Документы
Leung SW, Yuen PM. Ovarian Fibroma: A Review on the Clinical Characteristics, Diagnostic
Difficulties, and Management Options of 23 Cases. Gynecol Obstet Invest 2006;62:1–6
CA-125
• Normal value:
– CA 125 <= 35 U/mL
– Ca 125 II < 20 U/mL
• Non-mucinous epithelial carcinoma
Ueland FR, Li AJ. Serum biomarkers for evaluation of an dnexal mass for epithelial carcinoma of
the ovary, fallopian tube, or peritoneum. UpTodate.2018
CEA
• Normaly found: fetal or embryonic tissue
• Small amount present in colon
• Maybe elevated in malignancy that produce the
protein; mucinous cancer (GI or Ovary)
epithelial carcinoma
• Benign condition: mucinous cystadenoma of the
ovary
• LEVEL:
– Non smoker: < 3.8 mcg/L
– Smoker: < 5.5 mcg/L
Ueland FR, Li AJ. Serum biomarkers for evaluation of an dnexal mass for epithelial carcinoma of
the ovary, fallopian tube, or peritoneum. UpTodate.2018
CEA
• Normal cell product (protein polysavharidae)
oncofetal glycoprotein
• Low sensitivity and specificity not
recommended as a screening tool
• Primary use: colorectal cancer monitoring
Overexpress of CEA
Cancer/ malignan Benign
• Colon • IBD/ colitis
• Rectum • Pancreatitis
• Breast • COPD
• Lung • Renal disease
• Liver disease (hepatitis,
cirrosis)
• Smoker “healthy”
Konishi I, et.al. analysis of serum Ca 125, CEA, AFP, LDH Level in patients with ovarian tumorsNihon Sanka Fujinka
Gakkai Zasshi. 1986 Jun;38(6):827-36
RMI
RMI = U x M x CA125
ADNEX